Biological sciences

Definition

Biological sciences encompasses all the divisions of natural sciences examining various aspects of vital processes. The concept includes anatomy, physiology, cell biology, biochemistry and biophysics, and covers all organisms from microorganisms, animals to plants.

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Latest Research and Reviews

  • Protocols |

    The levels of monoamines and their cofactors in cerebrospinal fluid are strong indicators for dopamine and serotonin biosynthesis and turnover. This protocol describes a set of HPLC-based approaches for the quantitative detection of these molecules.

    • Marta Batllori
    • , Marta Molero-Luis
    • , Aida Ormazabal
    • , Mercedes Casado
    • , Cristina Sierra
    • , Angels García-Cazorla
    • , Manju Kurian
    • , Simon Pope
    • , Simon J Heales
    •  & Rafael Artuch
    Nature Protocols 12, 2359–2375
  • Research |

    The development of selective ubiquitin-specific protease-7 (USP7) inhibitors GNE-6640 and GNE-6776, which induce tumour cell death and reveal differential kinetics of Lys-48 and Lys-63-linked ubiquitin chain depolymerization by USP7.

    • Lorna Kategaya
    • , Paola Di Lello
    • , Lionel Rougé
    • , Richard Pastor
    • , Kevin R. Clark
    • , Jason Drummond
    • , Tracy Kleinheinz
    • , Eva Lin
    • , John-Paul Upton
    • , Sumit Prakash
    • , Johanna Heideker
    • , Mark McCleland
    • , Maria Stella Ritorto
    • , Dario R. Alessi
    • , Matthias Trost
    • , Travis W. Bainbridge
    • , Michael C. M. Kwok
    • , Taylur P. Ma
    • , Zachary Stiffler
    • , Bradley Brasher
    • , Yinyan Tang
    • , Priyadarshini Jaishankar
    • , Brian R. Hearn
    • , Adam R. Renslo
    • , Michelle R. Arkin
    • , Frederick Cohen
    • , Kebing Yu
    • , Frank Peale
    • , Florian Gnad
    • , Matthew T. Chang
    • , Christiaan Klijn
    • , Elizabeth Blackwood
    • , Scott E. Martin
    • , William F. Forrest
    • , James A. Ernst
    • , Chudi Ndubaku
    • , Xiaojing Wang
    • , Maureen H. Beresini
    • , Vickie Tsui
    • , Carsten Schwerdtfeger
    • , Robert A. Blake
    • , Jeremy Murray
    • , Till Maurer
    •  & Ingrid E. Wertz
  • Research |

    Using data from sixty thousand generations of the E. coli long-term evolution experiment, the authors shed new light on the processes that govern molecular evolution.

    • Benjamin H. Good
    • , Michael J. McDonald
    • , Jeffrey E. Barrick
    • , Richard E. Lenski
    •  & Michael M. Desai
  • Research |

    Metabolic flux analysis in mice reveals that lactate often acts as the primary carbon source for the tricarboxylic acid cycle both in normal tissues and in tumour microenvironments.

    • Sheng Hui
    • , Jonathan M. Ghergurovich
    • , Raphael J. Morscher
    • , Cholsoon Jang
    • , Xin Teng
    • , Wenyun Lu
    • , Lourdes A. Esparza
    • , Tannishtha Reya
    • , Le Zhan
    • , Jessie Yanxiang Guo
    • , Eileen White
    •  & Joshua D. Rabinowitz

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