A spatially oscillating two-dimensional waveguide array is used to realize a photonic topological insulator in synthetic dimensions with modal-space edge states, unidirectionality and robust topological protection.

A strategy using droplet-based and barcode-linked sequencing captures multiplex chromatin interactions at single-molecule precision, and here provides topological insight into chromatin structures and transcription in Drosophila.

The pattern of electrical resistivity in an unconventional superconductor at high magnetic fields and low temperatures across the nematic quantum critical point reveals two classic signatures of quantum criticality.

Many clonotypes in human B cell repertoires are shared, including between adult and umbilical cord blood repertoires, which indicates that this similarity is not driven only by exposure to common antigens.

Analyses of the output produced by large versus small teams of researchers and innovators demonstrate that their work differs systematically in the extent to which it disrupts or develops existing science and technology.

The ancestral tribosphenic therian chewing stroke is conserved in Monodelphis domestica, and couples tooth-row eversion and inversion in jaw opening and closing, respectively, with a rotational grinding stroke.

The ‘negative luminescence’ of a reverse-biased photodiode is harnessed to draw thermal energy from a nearby solid object, thereby realizing photonic cooling without the use of coherent laser radiation.

Analyses at single-cell resolution show that diverse subtypes of microglia exist during development and homeostasis of the central nervous system, and identify specific subsets of microglia associated with demyelination and neurodegenerative disease in mice and humans.

Bilateral sensory stimulation, which is used to treat post-traumatic stress disorder in humans, alleviates fear memory in mice through a circuit involving the superior colliculus and the medial thalamus.

Early-stage cancerous growths can look similar under the microscope, and whether they will form an invasive tumour is hard to predict. Genomic profiles of these growths in the human lung now enable such a prediction to be made.

Complex Earth system challenges can be addressed by incorporating spatial and temporal context into machine learning, especially via deep learning, and further by combining with physical models into hybrid models.

Nine years ago, the compound kynurenine was reported to be responsible for the dilation of blood vessels during a potentially fatal inflammatory condition. New evidence has now identified the true culprit.

The application of a new citation metric prompts a reassessment of the relationship between the size of scientific teams and research impact, and calls into question the trend to emphasize ‘big team’ science.

The link between sleep and cardiovascular disease is poorly understood. Findings in mice now show that disrupted sleep causes the brain to signal the bone marrow to boost white blood cell production, damaging blood vessels.

A treatment called eye-movement desensitization and reprocessing alleviates post-traumatic stress disorder through enigmatic mechanisms. A study in mice offers potential clues into the biological basis of this approach.

Meteorologist Kelvin Droegemeier emphasized the importance of private science funding in his first public speech since taking office.

Study suggests that making reviewers’ reports freely readable doesn’t compromise peer-review process.

Scientists on board German research icebreaker Polarstern hope to observe underwater ecosystem changing in real-time.

Innovation ministry’s decision to issue grant call using money meant for Hungarian Academy of Sciences’ operations sparks protests.

Researchers say the policy could intensify existing issues with research quality and misconduct.

A planned US$35-million upgrade could enable LIGO to spot one black-hole merger per hour by the mid-2020s.