Featured Content

  • Comment |

    Confusion about mesenchymal stem cells is making it easier for people to sell unproven treatments, warn Douglas Sipp, Pamela G. Robey and Leigh Turner.

    • Douglas Sipp
    • , Pamela G. Robey
    •  & Leigh Turner

  • Letter |

    A genome-wide association study of approximately 7,000 patients with neurodevelopmental disorders demonstrates that overall risk and clinical presentation in putative monogenic disorders is also influenced by common genetic variants present in the general population.

    • Mari E. K. Niemi
    • , Hilary C. Martin
    • , Daniel L. Rice
    • , Giuseppe Gallone
    • , Scott Gordon
    • , Martin Kelemen
    • , Kerrie McAloney
    • , Jeremy McRae
    • , Elizabeth J. Radford
    • , Sui Yu
    • , Jozef Gecz
    • , Nicholas G. Martin
    • , Caroline F. Wright
    • , David R. Fitzpatrick
    • , Helen V. Firth
    • , Matthew E. Hurles
    •  & Jeffrey C. Barrett

  • Announcement

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Current Issue |

Volume 561 Issue 7724

Latest Research

  • Letter |

    DEET interferes selectively with chemotaxis of Caenorhabditis elegans nematodes, and mutations in the str-217 gene or silencing of the pair of chemosensory neurons that express it makes worms DEET-resistant.

    • Emily J. Dennis
    • , May Dobosiewicz
    • , Xin Jin
    • , Laura B. Duvall
    • , Philip S. Hartman
    • , Cornelia I. Bargmann
    •  & Leslie B. Vosshall

  • Letter |

    Observations of a jet from a strongly magnetized neutron star reveal that strong magnetic fields do not prevent jet formation and suggest that stellar properties influence jet power.

    • J. van den Eijnden
    • , N. Degenaar
    • , T. D. Russell
    • , R. Wijnands
    • , J. C. A. Miller-Jones
    • , G. R. Sivakoff
    •  & J. V. Hernández Santisteban

  • Article |

    Combination therapy with the anti-HIV-1 monoclonal antibodies 3BNC117 and 10-1074 maintains long-term suppression in the absence of antiretroviral therapy in individuals with antibody-sensitive viral reservoirs.

    • Pilar Mendoza
    • , Henning Gruell
    • , Lilian Nogueira
    • , Joy A. Pai
    • , Allison L. Butler
    • , Katrina Millard
    • , Clara Lehmann
    • , Isabelle Suárez
    • , Thiago Y. Oliveira
    • , Julio C. C. Lorenzi
    • , Yehuda Z. Cohen
    • , Christoph Wyen
    • , Tim Kümmerle
    • , Theodora Karagounis
    • , Ching-Lan Lu
    • , Lisa Handl
    • , Cecilia Unson-O’Brien
    • , Roshni Patel
    • , Carola Ruping
    • , Maike Schlotz
    • , Maggi Witmer-Pack
    • , Irina Shimeliovich
    • , Gisela Kremer
    • , Eleonore Thomas
    • , Kelly E. Seaton
    • , Jill Horowitz
    • , Anthony P. West Jr
    • , Pamela J. Bjorkman
    • , Georgia D. Tomaras
    • , Roy M. Gulick
    • , Nico Pfeifer
    • , Gerd Fätkenheuer
    • , Michael S. Seaman
    • , Florian Klein
    • , Marina Caskey
    •  & Michel C. Nussenzweig

  • Article |

    Analyses of the relationships between temperature, moisture and seven key plant functional traits across the tundra and over time show that community height increased with warming across all sites, whereas other traits lagged behind predicted rates of change.

    • Anne D. Bjorkman
    • , Isla H. Myers-Smith
    • , Sarah C. Elmendorf
    • , Signe Normand
    • , Nadja Rüger
    • , Pieter S. A. Beck
    • , Anne Blach-Overgaard
    • , Daan Blok
    • , J. Hans C. Cornelissen
    • , Bruce C. Forbes
    • , Damien Georges
    • , Scott J. Goetz
    • , Kevin C. Guay
    • , Gregory H. R. Henry
    • , Janneke HilleRisLambers
    • , Robert D. Hollister
    • , Dirk N. Karger
    • , Jens Kattge
    • , Peter Manning
    • , Janet S. Prevéy
    • , Christian Rixen
    • , Gabriela Schaepman-Strub
    • , Haydn J. D. Thomas
    • , Mark Vellend
    • , Martin Wilmking
    • , Sonja Wipf
    • , Michele Carbognani
    • , Luise Hermanutz
    • , Esther Lévesque
    • , Ulf Molau
    • , Alessandro Petraglia
    • , Nadejda A. Soudzilovskaia
    • , Marko J. Spasojevic
    • , Marcello Tomaselli
    • , Tage Vowles
    • , Juha M. Alatalo
    • , Heather D. Alexander
    • , Alba Anadon-Rosell
    • , Sandra Angers-Blondin
    • , Mariska te Beest
    • , Logan Berner
    • , Robert G. Björk
    • , Agata Buchwal
    • , Allan Buras
    • , Katherine Christie
    • , Elisabeth J. Cooper
    • , Stefan Dullinger
    • , Bo Elberling
    • , Anu Eskelinen
    • , Esther R. Frei
    • , Oriol Grau
    • , Paul Grogan
    • , Martin Hallinger
    • , Karen A. Harper
    • , Monique M. P. D. Heijmans
    • , James Hudson
    • , Karl Hülber
    • , Maitane Iturrate-Garcia
    • , Colleen M. Iversen
    • , Francesca Jaroszynska
    • , Jill F. Johnstone
    • , Rasmus Halfdan Jørgensen
    • , Elina Kaarlejärvi
    • , Rebecca Klady
    • , Sara Kuleza
    • , Aino Kulonen
    • , Laurent J. Lamarque
    • , Trevor Lantz
    • , Chelsea J. Little
    • , James D. M. Speed
    • , Anders Michelsen
    • , Ann Milbau
    • , Jacob Nabe-Nielsen
    • , Sigrid Schøler Nielsen
    • , Josep M. Ninot
    • , Steven F. Oberbauer
    • , Johan Olofsson
    • , Vladimir G. Onipchenko
    • , Sabine B. Rumpf
    • , Philipp Semenchuk
    • , Rohan Shetti
    • , Laura Siegwart Collier
    • , Lorna E. Street
    • , Katharine N. Suding
    • , Ken D. Tape
    • , Andrew Trant
    • , Urs A. Treier
    • , Jean-Pierre Tremblay
    • , Maxime Tremblay
    • , Susanna Venn
    • , Stef Weijers
    • , Tara Zamin
    • , Noémie Boulanger-Lapointe
    • , William A. Gould
    • , David S. Hik
    • , Annika Hofgaard
    • , Ingibjörg S. Jónsdóttir
    • , Janet Jorgenson
    • , Julia Klein
    • , Borgthor Magnusson
    • , Craig Tweedie
    • , Philip A. Wookey
    • , Michael Bahn
    • , Benjamin Blonder
    • , Peter M. van Bodegom
    • , Benjamin Bond-Lamberty
    • , Giandiego Campetella
    • , Bruno E. L. Cerabolini
    • , F. Stuart Chapin III
    • , William K. Cornwell
    • , Joseph Craine
    • , Matteo Dainese
    • , Franciska T. de Vries
    • , Sandra Díaz
    • , Brian J. Enquist
    • , Walton Green
    • , Ruben Milla
    • , Ülo Niinemets
    • , Yusuke Onoda
    • , Jenny C. Ordoñez
    • , Wim A. Ozinga
    • , Josep Penuelas
    • , Hendrik Poorter
    • , Peter Poschlod
    • , Peter B. Reich
    • , Brody Sandel
    • , Brandon Schamp
    • , Serge Sheremetev
    •  & Evan Weiher

  • Letter |

    In mouse and human liver models, blood vessel perfusion and mechanical stretching release angiocrine signals from endothelial cells that lead to hepatocyte survival and liver growth.

    • Linda Lorenz
    • , Jennifer Axnick
    • , Tobias Buschmann
    • , Carina Henning
    • , Sofia Urner
    • , Shentong Fang
    • , Harri Nurmi
    • , Nicole Eichhorst
    • , Richard Holtmeier
    • , Kálmán Bódis
    • , Jong-Hee Hwang
    • , Karsten Müssig
    • , Daniel Eberhard
    • , Jörg Stypmann
    • , Oliver Kuss
    • , Michael Roden
    • , Kari Alitalo
    • , Dieter Häussinger
    •  & Eckhard Lammert

  • Letter |

    A scheme for implementing multi-step topological reorganization of a mechanical metamaterial is demonstrated, which proceeds autonomously, without the need for external control.

    • Corentin Coulais
    • , Alberico Sabbadini
    • , Fré Vink
    •  & Martin van Hecke
More Latest Research More Latest Research

Latest Reviews & Analysis

  • News & Views |

    Current biological sensors require bulky external power sources. Ultrathin solar cells have now been fabricated that can power flexible, wearable sensors for the precise and continuous monitoring of biological signals.

    • Shiming Zhang
    •  & Fabio Cicoira

  • News & Views |

    Contrary to previous assumptions, it seems the cells that line blood vessels are derived from more than one source. In addition to their known developmental path, they can arise from progenitors of embryonic blood cells.

    • M. Luisa Iruela-Arispe

  • News & Views |

    Increases in biomechanical forces in the liver’s blood vessels have now been shown to activate two mechanosensitive proteins. The proteins trigger blood-vessel cells to deploy regenerative factors that drive liver growth.

    • Sina Y. Rabbany
    •  & Shahin Rafii

  • News & Views |

    Mechanical structures have been made that exhibit self-guided, multi-step sequences of shape changes in response to an applied force. Such structures could have applications in flexible electronics and soft robotics.

    • Larry L. Howell

  • News & Views |

    Drug treatments for HIV infection require the long-term use of daily medication that can have toxic side effects. A pair of HIV-targeting antibodies might offer an alternative therapeutic approach.

    • Nancy L. Haigwood

  • News & Views |

    What Nature was saying 50 and 100 years ago.

More Reviews & Analysis More Reviews & Analysis

News & Comment

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Journal tools

Nature Outlook

Alzheimer’s disease

Giulio Bonasera

Alzheimer’s disease

Alzheimer’s disease is the most common form of dementia. For decades, researchers have sought a treatment to no avail, and our understanding of the condition is now being questioned.
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