The quest to decipher how the body’s cells sense touch

From a painful pinch to a soft caress, scientists are zooming in on the pressure-sensitive proteins that allow cells to detect tension and pressure.

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  • Human presomitic mesoderm cells derived in vitro demonstrate oscillations of the segmentation clock, thus providing a window into an otherwise inaccessible stage of human development.

    • Margarete Diaz-Cuadros
    • Daniel E. Wagner
    • Olivier Pourquié
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  • Populations of KRAS(G12C)-mutant cancer cells can rapidly bypass the effects of treatment with KRAS(G12C) inhibitors because a subset of cells escapes drug-induced quiescence by producing new KRAS(G12C) that is maintained in its active, drug-insensitive state.

    • Jenny Y. Xue
    • Yulei Zhao
    • Piro Lito
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  • A method of deposition of mixed-cation hybrid perovskite films as lattice-mismatched substrates for an α-FAPbI3 film is described, giving strains of up to 2.4 per cent while also stabilizing the metastable α-FAPbI3 phase for several hundred days.

    • Yimu Chen
    • Yusheng Lei
    • Sheng Xu
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  • A growth process in which protons decouple graphene from the underlying substrate greatly reduces the number of wrinkles that usually degrade large graphene films grown by chemical vapour deposition.

    • Guowen Yuan
    • Dongjing Lin
    • Libo Gao
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Materials science

Materials science

The materials that will give rise to the industries of the future are taking shape in laboratories around the world, but how many of them will get to market?
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