Latest Research

  • Letter |

    Biomechanical analyses of mammaliaform and cynodont fossils demonstrate that miniaturization drove the evolutionary transformation of the mammalian jaw, which preceded the optimization of bite force-to-joint load in the mandible

    • Stephan Lautenschlager
    • , Pamela G. Gill
    • , Zhe-Xi Luo
    • , Michael J. Fagan
    •  & Emily J. Rayfield
  • Letter |

    The retromer complex (the vacuolar protein sorting heterotrimer Vps26–Vps29–Vps35) has been resolved in association with membranes and the sorting nexin protein Vps5 using cryo-electron tomography.

    • Oleksiy Kovtun
    • , Natalya Leneva
    • , Yury S. Bykov
    • , Nicholas Ariotti
    • , Rohan D. Teasdale
    • , Miroslava Schaffer
    • , Benjamin D. Engel
    • , David. J. Owen
    • , John A. G. Briggs
    •  & Brett M. Collins
  • Letter |

    Time-asymmetric light transmission over the entire optical communications band is achieved using a silicon photonic structure with photonic modes that dynamically encircle an exceptional point in the optical domain.

    • Jae Woong Yoon
    • , Youngsun Choi
    • , Choloong Hahn
    • , Gunpyo Kim
    • , Seok Ho Song
    • , Ki-Yeon Yang
    • , Jeong Yub Lee
    • , Yongsung Kim
    • , Chang Seung Lee
    • , Jai Kwang Shin
    • , Hong-Seok Lee
    •  & Pierre Berini
  • Letter |

    During starvation, glyceraldehyde 3-phosphate dehydrogenase (GAPDH) targets GTPase-activating proteins to inhibit multiple intracellular transport pathways, thereby promoting energy homeostasis.

    • Jia-Shu Yang
    • , Jia-Wei Hsu
    • , Seung-Yeol Park
    • , Jian Li
    • , William M. Oldham
    • , Galina V. Beznoussenko
    • , Alexander A. Mironov
    • , Joseph Loscalzo
    •  & Victor W. Hsu
  • Letter |

    A silcrete flake with a 73,000-year-old cross-hatched ochre drawing, from Blombos Cave, South Africa, demonstrates that early Homo sapiens used a range of media and techniques to produce graphic representations.

    • Christopher S. Henshilwood
    • , Francesco d’Errico
    • , Karen L. van Niekerk
    • , Laure Dayet
    • , Alain Queffelec
    •  & Luca Pollarolo
  • Article |

    The tumour microenvironment determines which type of liver cancer develops, with transformed hepatocytes giving rise to intrahepatic cholangiocarcinoma or hepatocellular carcinoma depending or whether they are surrounded by cells undergoing necroptosis or apoptosis.

    • Marco Seehawer
    • , Florian Heinzmann
    • , Luana D’Artista
    • , Jule Harbig
    • , Pierre-François Roux
    • , Lisa Hoenicke
    • , Hien Dang
    • , Sabrina Klotz
    • , Lucas Robinson
    • , Grégory Doré
    • , Nir Rozenblum
    • , Tae-Won Kang
    • , Rishabh Chawla
    • , Thorsten Buch
    • , Mihael Vucur
    • , Mareike Roth
    • , Johannes Zuber
    • , Tom Luedde
    • , Bence Sipos
    • , Thomas Longerich
    • , Mathias Heikenwälder
    • , Xin Wei Wang
    • , Oliver Bischof
    •  & Lars Zender
  • Letter |

    The topological magnet Fe3Sn2 exhibits a giant nematic energy shift of a many-body electronic state, demonstrating anisotropic spin–orbit tunability.

    • Jia-Xin Yin
    • , Songtian S. Zhang
    • , Hang Li
    • , Kun Jiang
    • , Guoqing Chang
    • , Bingjing Zhang
    • , Biao Lian
    • , Cheng Xiang
    • , Ilya Belopolski
    • , Hao Zheng
    • , Tyler A. Cochran
    • , Su-Yang Xu
    • , Guang Bian
    • , Kai Liu
    • , Tay-Rong Chang
    • , Hsin Lin
    • , Zhong-Yi Lu
    • , Ziqiang Wang
    • , Shuang Jia
    • , Wenhong Wang
    •  & M. Zahid Hasan

Latest Reviews & Analysis

  • News & Views |

    What Nature was saying 50 and 100 years ago.

  • News & Views |

    Spinal-cord injury can render intact neuronal circuits functionally dormant. Targeted reduction of neuronal inhibition in the injured region has now enabled reactivation of these circuits in mice, restoring basic locomotion.

    • Grégoire Courtine
  • News & Views |

    Bird migration is influenced by weather, making it hard to predict when birds will pass through a particular place on their route. A model that forecasts bird migrations has been developed using radar data and weather information.

    • Mary Abraham
  • News & Views |

    Controlled long-distance transport of electron spins is required for a kind of electronics known as spintronics. Such transport has been realized in an antiferromagnet, the most common type of magnetic material.

    • Sergio M. Rezende
  • News & Views |

    Some bacteria make energy in a process that is accompanied by transfer of electrons to a mineral. A previously unknown electron-transfer pathway now reveals an energy-generation system used by bacteria in the human gut.

    • Laty A. Cahoon
    •  & Nancy E. Freitag

News & Comment

Nature Outlook

Alzheimer’s disease

Giulio Bonasera

Alzheimer’s disease

Alzheimer’s disease is the most common form of dementia. For decades, researchers have sought a treatment to no avail, and our understanding of the condition is now being questioned.

Nature events Directory