Biological techniques

Definition

Biological techniques are methods or procedures that are used to study living things. They include experimental and computational methods, approaches, protocols and tools for biological research.

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Latest Research and Reviews

  • Research |

    Danielle Posthuma and colleagues perform a large meta-analysis for intelligence and determine genetic overlap with several neuropsychiatric and metabolic traits. They find 15 new significant loci and implicate 40 new genes, most of which are predominantly expressed in the brain.

    • Suzanne Sniekers
    • , Sven Stringer
    • , Kyoko Watanabe
    • , Philip R Jansen
    • , Jonathan R I Coleman
    • , Eva Krapohl
    • , Erdogan Taskesen
    • , Anke R Hammerschlag
    • , Aysu Okbay
    • , Delilah Zabaneh
    • , Najaf Amin
    • , Gerome Breen
    • , David Cesarini
    • , Christopher F Chabris
    • , William G Iacono
    • , M Arfan Ikram
    • , Magnus Johannesson
    • , Philipp Koellinger
    • , James J Lee
    • , Patrik K E Magnusson
    • , Matt McGue
    • , Mike B Miller
    • , William E R Ollier
    • , Antony Payton
    • , Neil Pendleton
    • , Robert Plomin
    • , Cornelius A Rietveld
    • , Henning Tiemeier
    • , Cornelia M van Duijn
    •  & Danielle Posthuma
  • Research |

    When faced with hypoxic conditions, Mycobacterium tuberculosis adapts its metabolism to generate intermediates reserved for re-initiation of peptidoglycan biosynthesis that can be used as soon as it is re-exposed to normoxia.

    • Hyungjin Eoh
    • , Zhe Wang
    • , Emilie Layre
    • , Poonam Rath
    • , Roxanne Morris
    • , D. Branch Moody
    •  & Kyu Y. Rhee
  • Research |

    Joanna Howson and colleagues perform a genome-wide association study and meta-analysis for coronary artery disease in large, trans-ancestry cohorts. They identify 15 new loci and correlate these regions with cell-type-specific gene expression and plasma protein levels to find novel pathways and potential mechanisms of disease.

    • Joanna M M Howson
    • , Wei Zhao
    • , Daniel R Barnes
    • , Weang-Kee Ho
    • , Robin Young
    • , Dirk S Paul
    • , Lindsay L Waite
    • , Daniel F Freitag
    • , Eric B Fauman
    • , Elias L Salfati
    • , Benjamin B Sun
    • , John D Eicher
    • , Andrew D Johnson
    • , Wayne H H Sheu
    • , Sune F Nielsen
    • , Wei-Yu Lin
    • , Praveen Surendran
    • , Anders Malarstig
    • , Jemma B Wilk
    • , Anne Tybjærg-Hansen
    • , Katrine L Rasmussen
    • , Pia R Kamstrup
    • , Panos Deloukas
    • , Jeanette Erdmann
    • , Sekar Kathiresan
    • , Nilesh J Samani
    • , Heribert Schunkert
    • , Hugh Watkins
    • , CARDIoGRAMplusC4D
    • , Ron Do
    • , Daniel J Rader
    • , Julie A Johnson
    • , Stanley L Hazen
    • , Arshed A Quyyumi
    • , John A Spertus
    • , Carl J Pepine
    • , Nora Franceschini
    • , Anne Justice
    • , Alex P Reiner
    • , Steven Buyske
    • , Lucia A Hindorff
    • , Cara L Carty
    • , Kari E North
    • , Charles Kooperberg
    • , Eric Boerwinkle
    • , Kristin Young
    • , Mariaelisa Graff
    • , Ulrike Peters
    • , Devin Absher
    • , Chao A Hsiung
    • , Wen-Jane Lee
    • , Kent D Taylor
    • , Ying-Hsiang Chen
    • , I-Te Lee
    • , Xiuqing Guo
    • , Ren-Hua Chung
    • , Yi-Jen Hung
    • , Jerome I Rotter
    • , Jyh-Ming J Juang
    • , Thomas Quertermous
    • , Tzung-Dau Wang
    • , Asif Rasheed
    • , Philippe Frossard
    • , Dewan S Alam
    • , Abdulla al Shafi Majumder
    • , Emanuele Di Angelantonio
    • , Rajiv Chowdhury
    • , EPIC-CVD
    • , Yii-Der Ida Chen
    • , Børge G Nordestgaard
    • , Themistocles L Assimes
    • , John Danesh
    • , Adam S Butterworth
    •  & Danish Saleheen
  • Research |

    Two studies by Sugden et al. and Jin et al. show that endoglin regulates endothelial cell migration through VEGFR2 signalling and controls blood vessel diameter in response to blood flow.

    • Wade W. Sugden
    • , Robert Meissner
    • , Tinri Aegerter-Wilmsen
    • , Roman Tsaryk
    • , Elvin V. Leonard
    • , Jeroen Bussmann
    • , Mailin J. Hamm
    • , Wiebke Herzog
    • , Yi Jin
    • , Lars Jakobsson
    • , Cornelia Denz
    •  & Arndt F. Siekmann
  • Research |

    Environmental heterogeneity in three-spined stickleback pairs contributes to deviations from parallel evolution, but genomic targets of selection were more parallel between environmentally similar pairs, suggestive of a continuum of parallel evolution.

    • Yoel E. Stuart
    • , Thor Veen
    • , Jesse N. Weber
    • , Dieta Hanson
    • , Mark Ravinet
    • , Brian K. Lohman
    • , Cole J. Thompson
    • , Tania Tasneem
    • , Andrew Doggett
    • , Rebecca Izen
    • , Newaz Ahmed
    • , Rowan D. H. Barrett
    • , Andrew P. Hendry
    • , Catherine L. Peichel
    •  & Daniel I. Bolnick

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