Virology

Definition

Virology is the scientific discipline concerned with the study of the biology of viruses and viral diseases, including the distribution, biochemistry, physiology, molecular biology, ecology, evolution and clinical aspects of viruses.

Latest Research and Reviews

  • Research |

    Updates from the Human Microbiome Project analyse the largest known body-wide metagenomic profile of human microbiome personalization.

    • Jason Lloyd-Price
    • , Anup Mahurkar
    • , Gholamali Rahnavard
    • , Jonathan Crabtree
    • , Joshua Orvis
    • , A. Brantley Hall
    • , Arthur Brady
    • , Heather H. Creasy
    • , Carrie McCracken
    • , Michelle G. Giglio
    • , Daniel McDonald
    • , Eric A. Franzosa
    • , Rob Knight
    • , Owen White
    •  & Curtis Huttenhower
  • Research | | open

    Assembly of filamentous RSV particles is incompletely understood due to a lack of techniques suitable for live-cell imaging. Here Vanover et al. use labeled soybean agglutinin to selectively label RSV G protein and show how filamentous RSV assembly, initiated in the cytoplasm, uses G protein recycled from the plasma membrane.

    • Daryll Vanover
    • , Daisy V. Smith
    • , Emmeline L. Blanchard
    • , Eric Alonas
    • , Jonathan L. Kirschman
    • , Aaron W. Lifland
    • , Chiara Zurla
    •  & Philip J. Santangelo
  • Research | | open

    Zika virus infection can result in congenital disorders and cause disease in adults, and there is currently no approved vaccine. Here Shan et al. show that a single dose of a live-attenuated Zika vaccine prevents infection, testis damage and transmission to the fetus during pregnancy in different animal models.

    • Chao Shan
    • , Antonio E. Muruato
    • , Brett W. Jagger
    • , Justin Richner
    • , Bruno T. D. Nunes
    • , Daniele B. A. Medeiros
    • , Xuping Xie
    • , Jannyce G. C. Nunes
    • , Kaitlyn M. Morabito
    • , Wing-Pui Kong
    • , Theodore C. Pierson
    • , Alan D. Barrett
    • , Scott C. Weaver
    • , Shannan L. Rossi
    • , Pedro F. C. Vasconcelos
    • , Barney S. Graham
    • , Michael S. Diamond
    •  & Pei-Yong Shi
  • Research |

    Infection of the alga Emiliania huxleyi with its virus EhV results in the increased release of extracellular vesicles that impact viral decay and infection, suggesting that EhV exploits these extracellular vesicles for efficient viral infection during algal blooms.

    • Daniella Schatz
    • , Shilo Rosenwasser
    • , Sergey Malitsky
    • , Sharon G. Wolf
    • , Ester Feldmesser
    •  & Assaf Vardi
  • Research | | open

    APOBEC3G inhibits HIV-1 viral replication via catalytic and non-catalytic processes. Here the authors show that APOBEC3G binds single-stranded DNA as an active deaminase monomer, subsequently forming catalytic-inactive dimers that block reverse transcriptase-mediated DNA synthesis.

    • Michael Morse
    • , Ran Huo
    • , Yuqing Feng
    • , Ioulia Rouzina
    • , Linda Chelico
    •  & Mark C. Williams

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