Featured
-
-
Original Article |
Retinoschisin gene therapy in photoreceptors, Müller glia or all retinal cells in the Rs1h−/− mouse
- L C Byrne
- , B E Öztürk
- & J G Flannery
-
Original Article |
AAV-mediated expression of human PRELP inhibits complement activation, choroidal neovascularization and deposition of membrane attack complex in mice
- M T Birke
- , E Lipo
- & R Kumar-Singh
-
Original Article |
Intranasal administration of plasmid DNA nanoparticles yields successful transfection and expression of a reporter protein in rat brain
- B T Harmon
- , A E Aly
- & B L Waszczak
-
Original Article |
Deletion of CXCR4 in cardiomyocytes exacerbates cardiac dysfunction following isoproterenol administration
- E R Wang
- , A A Jarrah
- & S T Tarzami
-
Short Communication |
Variable correction of Artemis deficiency by I-Sce1-meganuclease-assisted homologous recombination in murine hematopoietic stem cells
- J Rivière
- , J Hauer
- & M Cavazzana
-
Original Article |
Specific reactivation of latent HIV-1 with designer zinc-finger transcription factors targeting the HIV-1 5′-LTR promoter
- P Wang
- , X Qu
- & H Zhu
-
Original Article |
Herpes simplex virus vector-mediated gene transfer of kynurenine aminotransferase improves detrusor overactivity in spinal cord-injured rats
- C Jia
- , N Yoshimura
- & L Liao
-
Original Article |
Efficient lung orthotopic tumor-growth suppression of oncolytic adenovirus complexed with RGD-targeted bioreducible polymer
- J Kim
- , H Y Nam
- & S W Kim
-
Original Article |
Long-term correction of biochemical and neurological abnormalities in MLD mice model by neonatal systemic injection of an AAV serotype 9 vector
- N Miyake
- , K Miyake
- & T Shimada
-
Short Communication |
Efficient delivery of lentiviral vectors into resting human CD4 T cells
- X Geng
- , G Doitsh
- & W C Greene
-
Short Communication
| Open AccessIntracisternal delivery of AAV9 results in oligodendrocyte and motor neuron transduction in the whole central nervous system of cats
- T Bucher
- , L Dubreil
- & B Joussemet
-
Short Communication |
Efficient gene delivery to the cone-enriched pig retina by dual AAV vectors
- P Colella
- , I Trapani
- & A Auricchio
-
Original Article |
Sonic hedgehog gene therapy increases the ability of the dystrophic skeletal muscle to regenerate after injury
- A Piccioni
- , E Gaetani
- & R Pola
-
Original Article |
Effect of bortezomib on the efficacy of AAV9.SERCA2a treatment to preserve cardiac function in a rat pressure-overload model of heart failure
- A H Chaanine
- , M Nonnenmacher
- & T Weber
-
Original Article |
Calpain-dependent clearance of the autophagy protein p62/SQSTM1 is a contributor to ΔPK oncolytic activity in melanoma
- A Colunga
- , D Bollino
- & L Aurelian
-
Original Article |
Elimination of contaminating cap genes in AAV vector virions reduces immune responses and improves transgene expression in a canine gene therapy model
- Z Wang
- , C L Halbert
- & A D Miller
-
Original Article
| Open AccessA macrophage-specific synthetic promoter for therapeutic application of adiponectin
- W S Kang
- , J S Kwon
- & Y Ahn
-
Original Article |
HSV-mediated p55TNFSR reduces neuropathic pain induced by HIV gp120 in rats through CXCR4 activity
- W Huang
- , W Zheng
- & S Hao
-
Original Article |
Restoring ciliary function to differentiated primary ciliary dyskinesia cells with a lentiviral vector
- L E Ostrowski
- , W Yin
- & J C Olsen
-
Original Article |
Gene transfer of integration defective anti-HSV-1 meganuclease to human corneas ex vivo
- H M Elbadawy
- , M Gailledrat
- & S Ferrari
-
Original Article |
Leptin gene therapy attenuates neuronal damages evoked by amyloid-β and rescues memory deficits in APP/PS1 mice
- R Pérez-González
- , M X Alvira-Botero
- & E Carro
-
Enabling Technologies |
Injection parameters and virus dependent choice of promoters to improve neuron targeting in the nonhuman primate brain
- W Lerchner
- , B Corgiat
- & B J Richmond
-
Original Article |
Modulation of Treg function improves adenovirus vector-mediated gene expression in the airway
- Y Nagai
- , M P Limberis
- & H Zhang
-
Enabling Technologies |
Quantitative morphological comparison of axon-targeting strategies for gene therapies directed to the nigro-striatal projection
- S Padmanabhan
- , T Kareva
- & R E Burke
-
Original Article |
Therapeutic safety of high myocardial expression levels of the molecular inotrope S100A1 in a preclinical heart failure model
- C Weber
- , I Neacsu
- & S T Pleger
-
Original Article |
CD40 ligand and tdTomato-armed vaccinia virus for induction of antitumor immune response and tumor imaging
- S Parviainen
- , M Ahonen
- & V Cerullo
-
Original Article |
A novel gene therapy strategy using secreted multifunctional anti-HIV proteins to confer protection to gene-modified and unmodified target cells
- A Falkenhagen
- , M Ameli
- & S Joshi
-
Original Article |
Intratumoral gene therapy versus intravenous gene therapy for distant metastasis control with 2-Diethylaminoethyl-Dextran Methyl Methacrylate Copolymer Non-Viral Vector–p53
- A Baliaka
- , P Zarogoulidis
- & L Sakkas
-
Original Article |
In the rat liver, Adenoviral gene transfer efficiency is comparable to AAV
- P S Montenegro-Miranda
- , V Pichard
- & P J Bosma
-
Original Article |
Enhanced antitumor immunotherapeutic effect of B-cell-based vaccine transduced with modified adenoviral vector containing type 35 fiber structures
- E-K Kim
- , H-S Seo
- & C-Y Kang
-
Original Article |
Toxicology study assessing efficacy and safety of repeated administration of lipid/DNA complexes to mouse lung
- E W F W Alton
- , A C Boyd
- & S Sumner-Jones
-
Original Article |
MicroRNA-210 overexpression induces angiogenesis and neurogenesis in the normal adult mouse brain
- L Zeng
- , X He
- & G-Y Yang
-
Original Article
| Open AccessSustained relief of neuropathic pain by AAV-targeted expression of CBD3 peptide in rat dorsal root ganglion
- G Fischer
- , B Pan
- & H Yu
-
Original Article
| Open AccessTherapeutic expression of hairpins targeting apolipoprotein B100 induces phenotypic and transcriptome changes in murine liver
- P Maczuga
- , J Verheij
- & P Konstantinova
-
Short Communication |
Liver-directed adeno-associated virus serotype 8 gene transfer rescues a lethal murine model of citrullinemia type 1
- R J Chandler
- , T N Tarasenko
- & P J McGuire
-
Original Article |
Pluronic–PEI copolymers enhance exon-skipping of 2′-O-methyl phosphorothioate oligonucleotide in cell culture and dystrophic mdx mice
- M Wang
- , B Wu
- & Q L Lu
-
Short Communication |
AAV-encoded OTC activity persisting to adulthood following delivery to newborn spfash mice is insufficient to prevent shRNA-induced hyperammonaemia
- S C Cunningham
- , C Y Kok
- & I E Alexander
-
Original Article |
Stable insulin-secreting ducts formed by reprogramming of cells in the liver using a three-gene cocktail and a PPAR agonist
- A Banga
- , L V Greder
- & J M W Slack
-
Original Article |
Adeno-associated virus type 6 is retrogradely transported in the non-human primate brain
- W San Sebastian
- , L Samaranch
- & K S Bankiewicz
-
Original Article |
Improved therapeutic effect on malignant glioma with adenoviral suicide gene therapy combined with temozolomide
- H Stedt
- , H Samaranayake
- & S Ylä-Herttuala
-
-
Original Article |
Inhibition of hepatic fibrosis with artificial microRNA using ultrasound and cationic liposome-bearing microbubbles
- D Yang
- , Y-H Gao
- & G Wang
-
Original Article |
PEGylated helper-dependent adenoviral vector expressing human Apo A-I for gene therapy in LDLR-deficient mice
- E Leggiero
- , D Astone
- & L Pastore
-
-
Mini Review |
Immunotherapy with gene-modified T cells: limiting side effects provides new challenges
- H J Stauss
- & E C Morris
-
Short Communication |
De-targeting by miR-143 decreases unwanted transgene expression in non-tumorigenic cells
- F Kopp
- , M Schnoedt
- & M Ogris
-
Original Article |
Downregulation of Stat3 in melanoma: reprogramming the immune microenvironment as an anticancer therapeutic strategy
- P U Emeagi
- , S Maenhout
- & K Breckpot
-
Original Article |
Long-term efficacy of ciliary muscle gene transfer of three sFlt-1 variants in a rat model of laser-induced choroidal neovascularization
- M El Sanharawi
- , E Touchard
- & F Behar-Cohen
-
Original Article |
Beneficial effects of parenteral GLP-1 delivery by cell therapy in insulin-deficient streptozotocin diabetic mice
- S Vasu
- , R C Moffett
- & P R Flatt
Browse broader subjects
Browse narrower subjects
- Cancer
- Cardiovascular diseases
- Dental diseases
- Endocrine system and metabolic diseases
- Eye diseases
- Gastrointestinal diseases
- Haematological diseases
- Immunological disorders
- Infectious diseases
- Kidney diseases
- Metabolic disorders
- Neurological disorders
- Nutrition disorders
- Oral diseases
- Psychiatric disorders
- Reproductive disorders
- Respiratory tract diseases
- Rheumatic diseases
- Skin diseases
- Trauma
- Urogenital diseases