Mice with human cells developed using ‘game-changing’ technique
Human cells injected into amniotic fluid find their way into fetal mouse organs
Human cells injected into amniotic fluid find their way into fetal mouse organs
A competition to develop computational approaches to detect ‘novelty’ in published papers will help metascientists to study how out-of-the-box research changes the scientific landscape.
Experiments in mice reveal an early postnatal window of opportunity for the effective transfer of genes to blood-cell-producing haematopoietic stem cells by injecting mice with gene-carrying lentiviral vectors. This approach showed therapeutic benefit in three mouse models of severe diseases, and could expand the applicability of haematopoietic stem-cell gene therapy in the clinic.