Local human-derived stressors combine with global ocean warming to threaten coral-reef persistence. Simultaneous reduction of human-derived stressors that originate on land, such as coastal run-off, and sea-based stressors, such as fishing pressure, resulted in greater coral-reef persistence before, during and after severe heat stress than did reduction of either alone.

How has river quality in Europe changed over time? A detailed analysis of invertebrate data provides a picture of biological recovery from past problems, but also points to remaining challenges.

An algorithm has been developed for constructing a 3D shape that follows an infinitely repeating path as it rolls under gravity. The approach could have applications in quantum computing and medical imaging.

Analysis of immune responses to SARS-CoV-2 at single-cell resolution reveals marked differences across human populations that are caused by previous infections and genetic variation. Natural selection and past reproduction with Neanderthals contributed to these differing immune responses and disparities in COVID-19 risk.