Coloured scanning electron micrograph of a T-cell and a brain cancer cell

Turbocharged CAR-T cells melt tumours in mice — using a trick from cancer cells

mmune cells armed with a mutation first identified in cancer cells gain potency but don’t turn cancerous themselves.

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  • Arachnoid cuff exit points create openings in the arachnoid barrier enabling the drainage of cerebrospinal fluid and exchange of molecules and cells between the dura and the subarachnoid space, therefore physically connecting the brain and the dura.

    • Leon C. D. Smyth
    • Di Xu
    • Jonathan Kipnis
    Article
  • Vectorial optoelectronic metasurfaces are described, showing that light pulses can be used to drive and direct local charge flows around symmetry-broken plasmonic nanostructures, leading to tunable responses in terahertz emission.

    • Jacob Pettine
    • Prashant Padmanabhan
    • Hou-Tong Chen
    ArticleOpen Access
  • Contrary to expectations from pollen and dust records, Southern Hemisphere subtropical regions experienced the greatest climatic moisture during glacial periods of the Late Pleistocene, which may not have been an obstacle to movement and expansion of animals and plants.

    • Rieneke Weij
    • J. M. Kale Sniderman
    • Jay Gordon
    Article
View of the inside of a particle UVX second-generation accelerator in Sao Paulo, Brazil

Brazil

In January 2023 Luiz Inácio Lula da Silva became president of Brazil, succeeding Jair Bolsonaro.
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