Nature

Neanderthal-like ‘mini-brains’ created in lab with CRISPR

Organoids that contain an ancient version of a gene that influences brain development are smaller and bumpier than those with human genes.

The next 20 years of human genomics must be more equitable and more open

By re-committing to data sharing, researchers can fulfil the long-delayed promise of the Human Genome Project.

Editorial 10 Feb 2021
Trust in COVID vaccines is growing

Survey spanning several countries finds encouraging trends, but researchers warn vaccine hesitancy could slow pandemic recovery.
Emiliano Rodríguez Mega

News 10 Feb 2021
SARS-CoV-2 infection is effectively treated and prevented by EIDD-2801
Angela Wahl
Lisa E. Gralinski
J. Victor Garcia

Article 09 Feb 2021
Daily briefing: Mysterious spike in ozone-killing chemicals is over

Rogue CFC emissions have halted after scientists raised the alarm. Plus, a WHO team’s visit to China has left some questions unanswered and prozac pollution can zombify fish.
Flora Graham

Nature Briefing 11 Feb 2021
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Current Issue 11 Feb 2021

News & Comment

How ‘killer’ T cells could boost COVID immunity in face of new variants

In the race against emerging coronavirus variants, researchers are looking beyond antibodies for clues to lasting protection from COVID-19.
Heidi Ledford

News 12 Feb 2021
Russian academics decry law change that threatens scientific outreach
Quirin Schiermeier

News 12 Feb 2021
COVID research updates: Vaccines spur antibody surge against a COVID variant

News 12 Feb 2021
Neanderthal-like ‘mini-brains’ created in lab with CRISPR
Ariana Remmel

News 11 Feb 2021
Trust in COVID vaccines is growing
Emiliano Rodríguez Mega

News 10 Feb 2021
China’s first Mars explorer arrives at the red planet
Smriti Mallapaty

News 10 Feb 2021
The broken promise that undermines human genome research
Kendall Powell

News Feature 10 Feb 2021

Latest Reviews & Analysis

- How the human genome transformed study of rare diseases
  
  Mendelian diseases are caused by mutations in a single gene. The first draft of the human genome, published in 2001, had broad implications for how these diseases are diagnosed, managed and prevented.
  
  Fowzan S. Alkuraya
  
  News & Views 10 Feb 2021
- Dynamics of RNA–protein interactions studied in living cells
  
  An understanding of how quickly biomolecules bind and dissociate in cells is crucial for developing quantitative models of biology, but measurements of these kinetics were possible only using purified proteins in vitro — until now.
  
  Olivia S. Rissland
  
  News & Views 10 Feb 2021
- Shedding squeezed light on dark matter
  
  Hypothetical particles called axions could constitute dark matter — the unseen component of the Universe. An experiment shows how quantum-manipulation technology can improve the sensitivity of axion detectors.
  
  Igor G. Irastorza
  
  News & Views 10 Feb 2021
- Breaking through the unknowns of the human reference genome
  
  Since the human genome was published in 2001, many of the gaps in the original sequence have been filled in, offering a more detailed understanding of genome regulation, structure and function.
  
  Karen H. Miga
  
  News & Views 10 Feb 2021
- From one human genome to a complex tapestry of ancestry
  
  In the 20 years since the first drafts of the human genome were made public, an explosion in genome sequencing has revealed how our evolutionary history and health can be understood by analysing the diversity in our genomes.
  
  Charles N. Rotimi
  Adebowale A. Adeyemo
  
  News & Views 10 Feb 2021
- Active membrane rupture spurs a range of cell deaths
  
  Sebastian Hiller
  Petr Broz
  
  News & Views 08 Feb 2021
- Signs of self-sustained inflammatory circuits in severe COVID pneumonia
  
  Kara J. Mould
  William J. Janssen
  
  News & Views 08 Feb 2021
- Developing fibrillated cellulose as a sustainable technological material
  
  Tian Li
  Chaoji Chen
  Liangbing Hu
  
  Perspective 03 Feb 2021
- Machine learning made easy for optimizing chemical reactions
  
  Jason E. Hein
  
  News & Views 03 Feb 2021

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Latest Research

mRNA vaccine-elicited antibodies to SARS-CoV-2 and circulating variants
Zijun Wang
Fabian Schmidt
Michel C. Nussenzweig

Article 10 Feb 2021
Macrophages provide a transient muscle stem cell niche via NAMPT secretion

Specific macrophage populations provide a transient niche that activates muscle stem cells after muscle injury and supply proliferation-inducing cues that govern the repair process mediated by these cells in both zebrafish and mouse injury models.
Dhanushika Ratnayake
Phong D. Nguyen
Peter D. Currie

Article 10 Feb 2021
Thermally reconfigurable monoclinic nematic colloidal fluids

Dispersion of colloidal disks in a nematic liquid crystal reveals several low-symmetry phases, including monoclinic colloidal nematic order, with interchange between them achieved through variations in temperature, concentration and surface charge.
Haridas Mundoor
Jin-Sheng Wu
Ivan I. Smalyukh

Article 10 Feb 2021
A decline in emissions of CFC-11 and related chemicals from eastern China

Atmospheric data and chemical-transport modelling show that CFC-11 emissions from eastern China have again decreased, after increasing in 2013–2017, and a delay in ozone-layer recovery has probably been avoided.
Sunyoung Park
Luke M. Western
Matthew Rigby

Article 10 Feb 2021
A decline in global CFC-11 emissions during 2018−2019

Atmospheric concentration measurements at remote sites around the world reveal an accelerated decline in the global mean CFC-11 concentration during 2018 and 2019, reversing recent trends and building confidence in the timely recovery of the stratospheric ozone layer.
Stephen A. Montzka
Geoffrey S. Dutton
Christina Theodoridi

Article 10 Feb 2021