Metabolic-dysfunction-associated steatohepatitis (MASH) is defined by lipid accumulation and inflammation, and makes liver cells enter a tumour-suppressive state called senescence while increasing cancer risk. Investigation of this paradox reveals that MASH-inducing diets trigger senescence by causing DNA damage. However, prolonged metabolic stress allows once-senescent liver cells to start dividing and progress to cancer.

The lack of methods for preparing miniature lasers directly on silicon wafers is holding back photonic technology in a range of applications, including machine learning. The solution could be to construct lasers in nanoscale trenches.

During pregnancy, several organs are rewired to support the health of the mother and the offspring. A molecular signalling pathway called RANK–RANKL drives the expansion of the layer that lines the inside of the intestine during pregnancy and lactation. This tissue remodelling process has a key role in mammalian life history.

The organization of bee society, and a suggestion that Latin be used as the international scientific language, in our weekly dip into Nature’s archive.