A phase I clinical trial of GD2-CAR T cells (immune cells engineered to target the molecule GD2) in children and young adults with diffuse midline gliomas — incurable cancers of the central nervous system — shows promising results. Several trial participants exhibited substantial improvements, and one child’s tumour has been undetectable for more than three years.

Promoting mutually beneficial relationships between plants and soil microbes that enhance nutrient acquisition by plants could improve crop production without increasing inorganic-fertilizer use. A mutation that causes an amino-acid substitution in a channel called CNGC15 in the plant cell’s nucleus boosts the formation of such endosymbiotic relationships.

US technology company Meta has produced an AI model that can directly translate speech in one language to speech in another. Two scientists discuss the technical feats and ethical questions that underpin this advance in machine translation.

A groundbreaking imaging method for tracking salt inside plant cells has rewritten knowledge of how roots handle toxic levels of sodium ions. The findings might aid efforts to boost plant resilience to stress driven by high levels of salt.