Can brain scans reveal behaviour? Bombshell study says not yet

Most studies linking features in brain imaging to traits such as cognitive abilities are too small to be reliable, argues a controversial analysis.

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  • Single-cell profiling of vagal sensory neurons from seven organs in mice and calcium-imaging-guided spatial transcriptomics reveal that interoceptive signals are coded through three distinct dimensions, allowing efficient processing of multiple signals in parallel using a combinatorial strategy.

    • Qiancheng Zhao
    • Chuyue D. Yu
    • Rui B. Chang
    Article Open Access
  • A genome-scale gain-of-function screen using overexpression of nearly 12,000 open reading frames (ORFs) identifies positive regulators of human T cell function and suggests that ORF-based screens could be applied clinically to improve T cell therapies.

    • Mateusz Legut
    • Zoran Gajic
    • Neville E. Sanjana
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Illustration of superhero wearing cape showing p53

p53: the tumour suppressor

Widely dubbed ‘the guardian of the genome’, the protein p53 provides important protection against cancer — when it is active, that is.
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