Nature

Record-breaking simulation hints at how climate shaped human migration

Model suggests that a shift in weather patterns in southern Africa might have contributed to the rise of Homo sapiens.

What's next for AlphaFold and the AI protein-folding revolution

DeepMind software that can predict the 3D shape of proteins is already changing biology.

Ewen Callaway
News Feature 13 Apr 2022
Women are under-represented in economics globally

They occupy fewer top positions at leading economics institutions than men, and are more likely to leave the profession early.

Brittney J. Miller
News 14 Apr 2022
Realization of Paris Agreement pledges may limit warming just below 2 °C

If all new and updated national climate change mitigation pledges stemming from the Paris Agreement are implemented in full and on time, then 21st-century warming could be limited to just below 2 degrees Celsius.

Malte Meinshausen
Jared Lewis
Bernd Hackmann
Article 13 Apr 2022
Daily briefing: Cave-dwelling fish have regional accents

Groups of blind Mexican fish that communicate using clicks appear to be developing cave-specific accents. Plus, the impact of COP26 pledges, and how machine learning is helping mathematicians.

Emma Stoye
Nature Briefing 14 Apr 2022
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Current Issue 14 Apr 2022

News & Comment

How Shanghai’s scientists are coping amid harsh COVID lockdown

From laps of the apartment to fears for students who desperately need data, four researchers speak about their lockdown experience.

Yvaine Ye

News 15 Apr 2022
Women are under-represented in economics globally
Brittney J. Miller
News 14 Apr 2022
What's next for AlphaFold and the AI protein-folding revolution
Ewen Callaway
News Feature 13 Apr 2022
Global science must stand up for Iran’s imprisoned scholars

Editorial 13 Apr 2022
Record-breaking simulation hints at how climate shaped human migration
Freda Kreier
News 13 Apr 2022
University culture wars over race theory recall 1920s fight to teach evolution
Adam Laats
World View 12 Apr 2022
Brain growth charts, discovery gap — the week in infographics

News 12 Apr 2022

Latest Reviews & Analysis

- Mental replays enable flexible navigation
  
  While rats pause to eat or rest during navigation tasks, neuronal sequences in the brain are replaying routes around moving obstacles, allowing the animals to reach their goals even in changing environments.
  
  Jérôme Epsztein
  
  News & Views 14 Apr 2022
- Net-zero commitments could limit warming to below 2 °C
  
  Analysis of climate pledges by nations at the COP26 meeting indicates that such commitments could ensure that global warming does not exceed 2 ºC before 2100 — but only if backed up by short-term policies.
  Zeke Hausfather
  Frances C. Moore
  
  News & Views 13 Apr 2022
- A detector that can learn the fingerprint of light
  
  The polarization, wavelength and power of a light wave can be simultaneously identified by a compact device made from twisted layers of carbon atoms — with a little help from an artificial neural network.
  Justin C. W. Song
  Yidong Chong
  
  News & Views 13 Apr 2022
- Mutational clocks tick differently across species
  
  Throughout life, cells accrue mutations. It now emerges that longer-lived animals acquire mutations at a slower rate than do short-lived species, potentially explaining why cancer risk does not increase with lifespan.
  Alexander N. Gorelick
  Kamila Naxerova
  
  News & Views 13 Apr 2022
- Self-activated adhesion receptor proteins visualized
  
  The inner workings of a family of proteins, known as adhesion G-protein-coupled receptors, have finally been visualized at high resolution — revealing the structural basis of their self-activation mechanism.
  Antony A. Boucard
  
  News & Views 13 Apr 2022
- A lengthy look at climate and its role in hominin evolution
  Michael D. Petraglia
  
  News & Views 13 Apr 2022
- Brain-inspired computing needs a master plan
  A. Mehonic
  A. J. Kenyon
  
  Perspective 13 Apr 2022
- From the archive: Tutankhanum’s tomb, and a floating fish nest from Bermuda
  
  News & Views 12 Apr 2022
- Insights from orangutans into the evolution of tool use
  Michael Haslam
  
  News & Views 12 Apr 2022

Nature is a Transformative Journal; authors can publish using the traditional publishing route OR via immediate gold Open Access.

Our Open Access option complies with funder and institutional requirements.

Latest Research articles

A solid-state electrolysis process for upcycling aluminium scrap

Xin Lu
Zhengyang Zhang
Tetsuya Nagasaka
Article 13 Apr 2022
Tethered peptide activation mechanism of the adhesion GPCRs ADGRG2 and ADGRG4

Cryo-electron microscopy structures of three adhesion G protein-coupled receptors (aGPCRs) complexes provide insight into the tethered activation mechanism of aGPCRs and show the potential for rational design of agonists.

Peng Xiao
Shengchao Guo
Xiao Yu
Article 13 Apr 2022
A dusty compact object bridging galaxies and quasars at cosmic dawn

An unusual ultraviolet compact object associated with a dusty starburst has been observed at a redshift of about 7.2, with a luminosity that falls between that of quasars and galaxies, possibly in transition between the two.

S. Fujimoto
G. B. Brammer
P. A. Oesch
Article 13 Apr 2022
Environmental factors shaping the gut microbiome in a Dutch population

A study in which gut microbiomes of 8,208 individuals from 2,756 families were characterized and correlated to 241 host and environmental factors defines microbiome patterns shared across diverse diseases and shows that the microbiome is shaped largely by environment and cohabitation.

R. Gacesa
A. Kurilshikov
R. K. Weersma
Article 13 Apr 2022
Structural basis for the tethered peptide activation of adhesion GPCRs

Adhesion GPCRs involved in cell and matrix interactions signal through a distinct self-cleavage, self-activation mechanism.

Yu-Qi Ping
Peng Xiao
Jin-Peng Sun
Article 13 Apr 2022

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Nature Outlook 29 Mar 2022

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