Regioselective functionalization of aliphatic carbon–hydrogen bonds is achieved using frustrated radical pairs generated from disilazide donors and an N-oxoammonium acceptor.

Three-dimensional deep neural networks can be trained to forecast global weather patterns, including extreme weather, with accuracy greater than or equal to that of the best numerical weather prediction models.

Induction of APOBEC3A in response to targeted therapies drives evolution of drug-tolerant persister cells, suggesting that its suppression may represent a potential therapeutic strategy in the prevention of acquired resistance to lung cancer targeted therapy.

Cryo-EM structures and analysis provide insight into the mechanisms by which basic helix–loop–helix transcription factors access E-box DNA sequences that are embedded within nucleosomes, and cooperate with other transcription factors.

Measurements from the Chang’e-1 and Chang’e-2 microwave instruments reveal an anomalously hot geothermal source on the Moon that is best explained by a roughly 50-kilometre-diameter granitic system below the geological feature known as Compton–Belkovich.