Nature

DeepMind’s AI for protein structure is coming to the masses

Machine-learning systems from the company and from a rival academic group are now open-source and freely accessible.

The US is boosting funding for research monkeys in the wake of COVID

The investments are promising but won’t fix the primate shortage, experts say.

Nidhi Subbaraman
News 15 Jul 2021
Deaths from COVID ‘incredibly rare’ among children

Studies find that overall risk of death or severe disease from COVID-19 is very low in kids.

Heidi Ledford
News 15 Jul 2021
A condensate-hardening drug blocks RSV replication in vivo

Cyclopamine and its chemical analogue A3E inhibit replication of human respiratory syncytial virus (RSV) by hardening the liquid–liquid phase-separated inclusion bodies, resulting in the inhibition of virus replication in the lungs of RSV-infected mice.

Jennifer Risso-Ballester
Marie Galloux
Ralf Altmeyer
Article 07 Jul 2021
Daily briefing: ‘Super-antibodies’ fight many coronavirus variants

Designer antibodies are based on those from people with very special immune systems. Plus, part of the Amazon is no longer a carbon sink, and why city heatwaves hit people unfairly.

Flora Graham
Nature Briefing 15 Jul 2021
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Current Issue 15 Jul 2021

News & Comment

Cooperation’s pros and cons, construction decarbonized, and into the wild: Books in brief

Andrew Robinson reviews five of the week’s best science picks.

Andrew Robinson

Book Review 16 Jul 2021
Massive DNA ‘Borg’ structures perplex scientists
- Amber Dance
News 16 Jul 2021
Astronomers push for global debate on giant satellite swarms
- Alexandra Witze
News 16 Jul 2021
Influential US climate report moves ahead — under new leadership
- Jeff Tollefson
News 16 Jul 2021
The vanishing neutrinos that could upend fundamental physics
- Davide Castelvecchi
News 16 Jul 2021
Deaths from COVID ‘incredibly rare’ among children
- Heidi Ledford
News 15 Jul 2021
DeepMind’s AI for protein structure is coming to the masses
- Ewen Callaway
News 15 Jul 2021

Latest Reviews & Analysis

- Receptor–enzyme complex structures show how receptors start to switch off
  
  The structure of rhodopsin, an archetypal member of the G-protein-coupled family of receptors, in complex with its specific kinase enzyme, reveals the molecular mechanism of the first step of receptor inactivation.
  
  Vsevolod V. Gurevich
  Eugenia V. Gurevich
  
  News & Views 14 Jul 2021
- Deciphering metabolism, one microbe at a time
  
  Small molecules produced and modified by gut microorganisms can influence human physiology. An atlas of metabolic outputs of diverse gut microbes offers new ways to decipher the microbial mechanisms behind their production.
  William F. Kindschuh
  Tal Korem
  
  News & Views 14 Jul 2021
- Southeast Amazonia is no longer a carbon sink
  
  Atmospheric measurements show that deforestation and rapid local warming have reduced or eliminated the capacity of the eastern Amazonian forest to absorb carbon dioxide — with worrying implications for future global warming.
  Scott Denning
  
  News & Views 14 Jul 2021
- Measurement-based system provides quantum control of nanoparticles
  
  Precise measurements of the position of a levitating nanosphere have been used to control forces that damp the nanosphere’s motion — potentially opening the way to quantum control of larger objects.
  Tania S. Monteiro
  
  News & Views 14 Jul 2021
- A protective signal between the brain’s supporting cells in Alzheimer’s disease
  
  In a mouse model of Alzheimer’s disease, interleukin-3 protein released by cells called astrocytes activates microglia, the immune cells of the brain. These then cluster around disease-associated protein aggregates and help to clear them.
  Jerika J. Barron
  Anna V. Molofsky
  
  News & Views 14 Jul 2021
- Designing the next generation of proton-exchange membrane fuel cells
  Kui Jiao
  Jin Xuan
  Michael D. Guiver
  
  Perspective 14 Jul 2021
- From the archive
  
  News & Views 13 Jul 2021
- After the pandemic: perspectives on the future trajectory of COVID-19
  Amalio Telenti
  Ann Arvin
  Herbert W. Virgin
  
  Perspective 08 Jul 2021
- Human genetic variants identified that affect COVID susceptibility and severity
  Samira Asgari
  Lionel A. Pousaz
  
  News & Views 08 Jul 2021

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Latest Research articles

Highly accurate protein structure prediction with AlphaFold

John Jumper
Richard Evans
Demis Hassabis
Article 15 Jul 2021
cGAS-like receptors sense RNA and control 3′2′-cGAMP signaling in Drosophila

Kailey M. Slavik
Benjamin R. Morehouse
Philip J. Kranzusch
Article 14 Jul 2021
Two cGAS-like receptors induce antiviral immunity in Drosophila

Andreas Holleufer
Kasper Grønbjerg Winther
Rune Hartmann
Article 14 Jul 2021
SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape

Tyler N. Starr
Nadine Czudnochowski
Gyorgy Snell
Article 14 Jul 2021
A lithium-isotope perspective on the evolution of carbon and silicon cycles

Analysis of shallow-water marine carbonate samples from 101 stratigraphic units allows construction of a record of lithium isotopes from the past 3 billion years, tracking the evolution of the global carbon and silicon cycles.

Boriana Kalderon-Asael
Joachim A. R. Katchinoff
Philip A. E. Pogge von Strandmann
Article 14 Jul 2021

Researchers are rethinking the nature and potential of matter. From new metal mixes that form more efficient catalysts to bio-inspired super-black products, their work is driving advances in manufacturing, drug discovery and product design.

Nature Index 30 Jun 2021