Featured
-
-
Article
| Open AccessGenetic risk impacts the association of menopausal hormone therapy with colorectal cancer risk
- Yu Tian
- , Yi Lin
- & Jenny Chang-Claude
-
Review Article |
Incidental pathogenic germline alterations detected through liquid biopsy in patients with solid tumors: prevalence, clinical utility and implications
- Juan Carlos Laguna
- , Belén Pastor
- & Laura Mezquita
-
Article |
A cellular model provides insights into the pathogenicity of the oncogenic FOXL2 somatic variant p.Cys134Trp
- Laetitia Herman
- , Angélique Amo
- & Anne-Laure Todeschini
-
Article
| Open AccessCancer predisposition signaling in Beckwith-Wiedemann Syndrome drives Wilms tumor development
- Snehal Nirgude
- , Natali S. Sobel Naveh
- & Jennifer M. Kalish
-
Article
| Open AccessCharacterisation of FLT3 alterations in childhood acute lymphoblastic leukaemia
- Angela Gutierrez-Camino
- , Chantal Richer
- & Daniel Sinnett
-
Article
| Open AccessHopes, concerns, satisfaction and regret in a precision medicine trial for childhood cancer: a mixed-methods study of parent and patient perspectives
- Claire E. Wakefield
- , Kate Hetherington
- & David S. Ziegler
-
Article |
Subclonal accumulation of immune escape mechanisms in microsatellite instability-high colorectal cancers
- Yuta Kobayashi
- , Atsushi Niida
- & Koshi Mimori
-
Article
| Open AccessProbing the diabetes and colorectal cancer relationship using gene – environment interaction analyses
- Niki Dimou
- , Andre E. Kim
- & Ulrike Peters
-
Article
| Open AccessPersonALL: a genetic scoring guide for personalized risk assessment in pediatric B-cell precursor acute lymphoblastic leukemia
- Gábor Bedics
- , Bálint Egyed
- & Donát Alpár
-
Review Article
| Open AccessRisk-reducing surgery for individuals with cancer-predisposing germline pathogenic variants and no personal cancer history: a review of current UK guidelines
- Rebecca L. McCarthy
- , Ellen Copson
- & Ramsey I. Cutress
-
Article
| Open AccessEvaluation of DNA methylation biomarkers ASCL1 and LHX8 on HPV-positive self-collected samples from primary HPV-based screening
- Lisanne Verhoef
- , Maaike C. G. Bleeker
- & Daniëlle A. M. Heideman
-
-
Article
| Open AccessPhase I/II sequencing study of azacitidine, epacadostat, and pembrolizumab in advanced solid tumors
- Jason J. Luke
- , Marwan Fakih
- & Aung Naing
-
Article |
Efficacy of front-line treatment for hormone receptor-positive HER2-negative metastatic breast cancer with germline BRCA1/2 mutation
- J.-S. Frenel
- , A. Lusque
- & T. de La Motte Rouge
-
Article |
Cancer in Costello syndrome: a systematic review and meta-analysis
- Esteban Astiazaran-Symonds
- , Gina M. Ney
- & Douglas R. Stewart
-
Article
| Open AccessGenomic ALK alterations in primary and relapsed neuroblastoma
- Carolina Rosswog
- , Jana Fassunke
- & Matthias Fischer
-
Review Article
| Open AccessAn old friend with a new face: tRNA-derived small RNAs with big regulatory potential in cancer biology
- Arianna Di Fazio
- & Monika Gullerova
-
Article
| Open AccessCritical evaluation of molecular tumour board outcomes following 2 years of clinical practice in a Comprehensive Cancer Centre
- Alexander Scheiter
- , Frederik Hierl
- & Kirsten Utpatel
-
Article |
Exome sequencing of affected duos and trios uncovers PRUNE2 as a novel prostate cancer predisposition gene
- Marta Cardoso
- , Sofia Maia
- & Manuel R. Teixeira
-
Comment |
Synthetic miR-34a against solid tumours: a predictable failure
- Sophie Mockly
- & Hervé Seitz
-
Article
| Open AccessClinical utility of liquid biopsy and integrative genomic profiling in early-stage and oligometastatic cancer patients treated with radiotherapy
- Guadalupe A. Cifuentes
- , Adrián Santiago
- & Rubén Cabanillas
-
Article
| Open AccessDisentangling the aetiological pathways between body mass index and site-specific cancer risk using tissue-partitioned Mendelian randomisation
- Genevieve M. Leyden
- , Michael P. Greenwood
- & Tom G. Richardson
-
Comment |
Age distribution and a multi-stage theory of carcinogenesis: 70 years on
- Anna Wilkins
- , Richard Corbett
- & Rosalind Eeles
-
Article |
YTHDF2-mediated FGF14-AS2 decay promotes osteolytic metastasis of breast cancer by enhancing RUNX2 mRNA translation
- Ming Zhang
- , Jue Wang
- & Changyan Ma
-
Article |
Outcomes of patients with HER2-negative metastatic breast cancer after platinum- and non-platinum-based first-line chemotherapy among patients with and without pathogenic germline BRCA1/2 mutations
- William Jacot
- , Amélie Lusque
- & Suzette Delaloge
-
Article
| Open AccessGenome wide DNA methylation analysis identifies novel molecular subgroups and predicts survival in neuroblastoma
- H. Lalchungnunga
- , Wen Hao
- & Gordon Strathdee
-
Article
| Open AccessGenomic landscape of pleural and peritoneal mesothelioma tumours
- Stefanie Hiltbrunner
- , Zoe Fleischmann
- & Alessandra Curioni-Fontecedro
-
Article |
Somatic hits in mismatch repair genes in colorectal cancer among non-seminoma testicular cancer survivors
- Berbel L. M. Ykema
- , Emilie C. H. Breekveldt
- & Monique E. van Leerdam
-
Editorial |
AIP: A double agent? The tissue-specific role of AIP as a tumour suppressor or as an oncogene
- Oliver Haworth
- & Márta Korbonits
-
Article |
Clinical and genomic correlates of imatinib response in melanomas with KIT alterations
- Seungyeon Jung
- , Emma Armstrong
- & Douglas B. Johnson
-
Article |
Prognostic significance of pathogenic variants in BRCA1, BRCA2, ATM and PALB2 genes in men undergoing hormonal therapy for advanced prostate cancer
- Hiroko Kimura
- , Kei Mizuno
- & Shusuke Akamatsu
-
Review Article |
Is loss of p53 a driver of ductal carcinoma in situ progression?
- Rhiannon L. Morrissey
- , Alastair M. Thompson
- & Guillermina Lozano
-
Article |
Clinicopathological and molecular characteristics of RSPO fusion-positive colorectal cancer
- Taiki Hashimoto
- , Daisuke Takayanagi
- & Shigeki Sekine
-
Article |
Stepwise evolutionary genomics of early-stage lung adenocarcinoma manifesting as pure, heterogeneous and part-solid ground-glass nodules
- Hao Li
- , Zewen Sun
- & Jun Wang
-
Article |
Predicted leukocyte telomere length and risk of germ cell tumours
- Shannon S. Cigan
- , John J. Meredith
- & Jenny N. Poynter
-
Review Article
| Open AccessLiquid biopsies to monitor and direct cancer treatment in colorectal cancer
- Gianluca Mauri
- , Pietro Paolo Vitiello
- & Alberto Bardelli
-
Article |
The impact of oophorectomy on survival from breast cancer in patients with CHEK2 mutations
- Joanna Tomiczek-Szwiec
- , Marek Szwiec
- & P. Wandzel
-
Article
| Open AccessBRCA1 and BRCA2 pathogenic variants and prostate cancer risk: systematic review and meta-analysis
- Tommy Nyberg
- , Marc Tischkowitz
- & Antonis C. Antoniou
-
Review Article
| Open AccessProstate cancer risk in men of differing genetic ancestry and approaches to disease screening and management in these groups
- Jana McHugh
- , Edward J. Saunders
- & Rosalind Eeles
-
Article
| Open AccessPhenome-wide association study (PheWAS) of colorectal cancer risk SNP effects on health outcomes in UK Biobank
- Xiaomeng Zhang
- , Xue Li
- & Evropi Theodoratou
-
Article
| Open AccessImpact of molecular tumour board discussion on targeted therapy allocation in advanced prostate cancer
- Peter H. J. Slootbeek
- , Iris S. H. Kloots
- & Niven Mehra
-
Article |
The HOXB13 variant X285K is associated with clinical significance and early age at diagnosis in African American prostate cancer patients
- Rong Na
- , Jun Wei
- & William B. Isaacs
-
Review Article
| Open AccessUnravelling similarities and differences in the role of circular and linear PVT1 in cancer and human disease
- Debora Traversa
- , Giorgia Simonetti
- & Clelia Tiziana Storlazzi
-
Review Article
| Open AccessLong non-coding RNAs are involved in alternative splicing and promote cancer progression
- Jiawei Ouyang
- , Yu Zhong
- & Wei Xiong
-
Article |
Bevacizumab-induced hypertension and proteinuria: a genome-wide study of more than 1000 patients
- Julia C. F. Quintanilha
- , Jin Wang
- & Federico Innocenti
-
Article |
Depiction of the genomic and genetic landscape identifies CCL5 as a protective factor in colorectal neuroendocrine carcinoma
- Dong Chen
- , Xuanwen Bao
- & Peng Zhao
-
Review Article |
BRCA-mutant pancreatic ductal adenocarcinoma
- Eleonora Lai
- , Pina Ziranu
- & Mario Scartozzi
-
Review Article |
The breast is yet to come: current and future utility of circulating tumour DNA in breast cancer
- Brad A. Davidson
- , Sarah Croessmann
- & Ben H. Park
-
Editorial |
Profiling circulating tumour cells and cell free DNA together in metastatic colon cancer
- Thomas Friend
- & Justin Stebbing