Featured
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Article
| Open AccessEvaluation of DNA methylation biomarkers ASCL1 and LHX8 on HPV-positive self-collected samples from primary HPV-based screening
- Lisanne Verhoef
- , Maaike C. G. Bleeker
- & Daniëlle A. M. Heideman
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Article
| Open AccessPhase I/II sequencing study of azacitidine, epacadostat, and pembrolizumab in advanced solid tumors
- Jason J. Luke
- , Marwan Fakih
- & Aung Naing
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Review Article
| Open AccessAn old friend with a new face: tRNA-derived small RNAs with big regulatory potential in cancer biology
- Arianna Di Fazio
- & Monika Gullerova
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Article |
YTHDF2-mediated FGF14-AS2 decay promotes osteolytic metastasis of breast cancer by enhancing RUNX2 mRNA translation
- Ming Zhang
- , Jue Wang
- & Changyan Ma
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Article
| Open AccessGenome wide DNA methylation analysis identifies novel molecular subgroups and predicts survival in neuroblastoma
- H. Lalchungnunga
- , Wen Hao
- & Gordon Strathdee
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Article |
Somatic hits in mismatch repair genes in colorectal cancer among non-seminoma testicular cancer survivors
- Berbel L. M. Ykema
- , Emilie C. H. Breekveldt
- & Monique E. van Leerdam
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Article |
Stepwise evolutionary genomics of early-stage lung adenocarcinoma manifesting as pure, heterogeneous and part-solid ground-glass nodules
- Hao Li
- , Zewen Sun
- & Jun Wang
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Article
| Open AccessBRCA1 and BRCA2 pathogenic variants and prostate cancer risk: systematic review and meta-analysis
- Tommy Nyberg
- , Marc Tischkowitz
- & Antonis C. Antoniou
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Article
| Open AccessPhenome-wide association study (PheWAS) of colorectal cancer risk SNP effects on health outcomes in UK Biobank
- Xiaomeng Zhang
- , Xue Li
- & Evropi Theodoratou
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Article |
Depiction of the genomic and genetic landscape identifies CCL5 as a protective factor in colorectal neuroendocrine carcinoma
- Dong Chen
- , Xuanwen Bao
- & Peng Zhao
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Editorial |
Profiling circulating tumour cells and cell free DNA together in metastatic colon cancer
- Thomas Friend
- & Justin Stebbing
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Comment |
RNA N6-methyladenosine: a new player in autophagy-mediated anti-cancer drug resistance
- Arumugam Paramasivam
- & Jayaseelan Vijayashree Priyadharsini
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Comment |
Sex bias of females in survival from cancer and infections. Is X the answer?
- Abdullah Al Emran
- , Stuart J. Gallagher
- & Peter Hersey
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Review Article
| Open AccessRoles of mitochondria in the hallmarks of metastasis
- Adam D. Scheid
- , Thomas C. Beadnell
- & Danny R. Welch
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Article
| Open AccessCancer incidence and spectrum among children with genetically confirmed Beckwith-Wiedemann spectrum in Germany: a retrospective cohort study
- Sümeyye Cöktü
- , Claudia Spix
- & Christian P. Kratz
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Perspective
| Open AccessIntegrating DNA methylation measures to improve clinical risk assessment: are we there yet? The case of BRCA1 methylation marks to improve clinical risk assessment of breast cancer
- Ee Ming Wong
- , Melissa C. Southey
- & Mary Beth Terry
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Review Article
| Open AccessPrinciples and mechanisms of non-genetic resistance in cancer
- Charles C. Bell
- & Omer Gilan
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Article
| Open AccessYY1 targets tubulin polymerisation-promoting protein to inhibit migration, invasion and angiogenesis in pancreatic cancer via p38/MAPK and PI3K/AKT pathways
- Qun Chen
- , Chuang Yang
- & Kui-Rong Jiang
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Article
| Open AccessEZH2 cooperates with E2F1 to stimulate expression of genes involved in adrenocortical carcinoma aggressiveness
- Houda Tabbal
- , Amandine Septier
- & Pierre Val
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Article
| Open AccessMolecular heterogeneity and early metastatic clone selection in testicular germ cell cancer development
- Lambert C. J. Dorssers
- , Ad J. M. Gillis
- & Leendert H. J. Looijenga
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Article
| Open AccessPrimary constitutional MLH1 epimutations: a focal epigenetic event
- Estela Dámaso
- , Adela Castillejo
- & Gabriel Capellá
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Letter to the Editor
| Open AccessReply to ‘Comment on ‘A meta-analysis of CXCL12 expression for cancer prognosis”
- Alex Gordon-Weeks
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Mini Review
| Open AccessInhibition of histone deacetylases in cancer therapy: lessons from leukaemia
- Elena Ceccacci
- & Saverio Minucci
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Genetics and Genomics
| Open AccessHypermethylation of genes in testicular embryonal carcinomas
- Hoi-Hung Cheung
- , Yanzhou Yang
- & Wai-Yee Chan
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Molecular Diagnostics
| Open AccessPotential of DNA methylation in rectal cancer as diagnostic and prognostic biomarkers
- Ruth Exner
- , Walter Pulverer
- & Gerda Egger
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Genetics and Genomics
| Open AccessIdentification of Endoglin as an epigenetically regulated tumour-suppressor gene in lung cancer
- K O’Leary
- , A Shia
- & P Schmid
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Review
| Open AccessClinical utility of RASSF1A methylation in human malignancies
- A M Grawenda
- & E O'Neill
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Mini Review
| Open AccessNon-genetic cancer cell plasticity and therapy-induced stemness in tumour relapse: ‘What does not kill me strengthens me’
- A O Pisco
- & S Huang
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Translational Therapeutics
| Open AccessExpression and DNA methylation of TNF, IFNG and FOXP3 in colorectal cancer and their prognostic significance
- S K Ganapathi
- , A D Beggs
- & D Kumar
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Molecular Diagnostics
| Open Accessβ-Arrestin1 promotes the progression of chronic myeloid leukaemia by regulating BCR/ABL H4 acetylation
- R Qin
- , K Li
- & L Zou
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Translational Therapeutics
| Open AccessEpigenetic silencing of miRNA-9 is associated with HES1 oncogenic activity and poor prognosis of medulloblastoma
- G Fiaschetti
- , L Abela
- & M A Grotzer
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Editorial
| Open AccessJust another brick in the wall: unravelling the epigenetic mechanism underlying tumour initiation of testicular germ cell cancer
- R Buettner
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Molecular Diagnostics
| Open AccessEvidence that active demethylation mechanisms maintain the genome of carcinoma in situ cells hypomethylated in the adult testis
- D G Kristensen
- , J E Nielsen
- & K Almstrup
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Molecular Diagnostics
| Open AccessEpigenetic status of LINE-1 predicts clinical outcome in early-stage rectal cancer
- A Benard
- , C J H van de Velde
- & D S B Hoon
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Translational Therapeutics
| Open AccessAerosolised 5-azacytidine suppresses tumour growth and reprogrammes the epigenome in an orthotopic lung cancer model
- M D Reed
- , C S Tellez
- & S A Belinsky
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Molecular Diagnostics
| Open AccessLSD1-mediated epigenetic modification contributes to proliferation and metastasis of colon cancer
- J Ding
- , Z-M Zhang
- & Z-S Yan
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Molecular Diagnostics
| Open AccessSomatostatin Receptor 1, a novel EBV-associated CpG hypermethylated gene, contributes to the pathogenesis of EBV-associated gastric cancer
- J Zhao
- , Q Liang
- & J Yu
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Genetics and Genomics
| Open AccessVan-Gogh-like 2 antagonises the canonical WNT pathway and is methylated in colorectal cancers
- G Piazzi
- , M Selgrad
- & L Ricciardiello
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Molecular Diagnostics
| Open AccessING1b-inducible microRNA203 inhibits cell proliferation
- J Chen
- , U M Tran
- & K Riabowol
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Mini Review
| Open AccessHistone deacetylase inhibitors as radiosensitisers: effects on DNA damage signalling and repair
- B Groselj
- , N L Sharma
- & A E Kiltie
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Molecular Diagnostics
| Open AccessPrognostic significance of aberrantly silenced ANPEP expression in prostate cancer
- K D Sørensen
- , M O Abildgaard
- & T F Ørntoft
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Molecular Diagnostics
| Open AccessThe epigenetic landscape of oral squamous cell carcinoma
- P V Jithesh
- , J M Risk
- & R J Shaw
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Genetics and Genomics
| Open AccessThe collagen prolyl hydroxylases are novel transcriptionally silenced genes in lymphoma
- E Hatzimichael
- , C Lo Nigro
- & T Crook
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Translational Therapeutics
| Open AccessEpigenetic remodelling of gene expression profiles of neoplastic and normal tissues: immunotherapeutic implications
- S Coral
- , A Covre
- & M Maio
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Genetics and Genomics
| Open AccessSite-specific CpG methylation in the CCAAT/enhancer binding protein delta (CEBPδ) CpG island in breast cancer is associated with metastatic relapse
- C Palmieri
- , M Monteverde
- & T Crook
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Molecular Diagnostics
| Open AccessMixed lineage leukaemia-4 regulates cell-cycle progression and cell viability and its depletion suppresses growth of xenografted tumour in vivo
- K I Ansari
- , S Kasiri
- & S S Mandal
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Molecular Diagnostics
| Open AccessMethylation of the calcium channel regulatory subunit α2δ-3 (CACNA2D3) predicts site-specific relapse in oestrogen receptor-positive primary breast carcinomas
- C Palmieri
- , B Rudraraju
- & T Crook
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Molecular Diagnostics
| Open AccessNT5E (CD73) is epigenetically regulated in malignant melanoma and associated with metastatic site specificity
- H Wang
- , S Lee
- & T Crook
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Translational Therapeutics
| Open AccessThe cyclin-dependent kinase inhibitor p57Kip2 is epigenetically regulated in carboplatin resistance and results in collateral sensitivity to the CDK inhibitor seliciclib in ovarian cancer
- H M Coley
- , N A M Safuwan
- & T Crook