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Article
| Open AccessA UK prospective multicentre decision impact, decision conflict and economic evaluation of the 21-gene assay in women with node+ve, hormone receptor+ve, HER2-ve breast cancer
- Simon Holt
- , Mark Verrill
- & Saira Khawaja
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Article
| Open AccessIntegrated genomic and transcriptomic analysis reveals the activation of PI3K signaling pathway in HPV-independent cervical cancers
- Yi Wang
- , Misi He
- & Huijuan Yang
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Article
| Open AccessCharacterisation of FLT3 alterations in childhood acute lymphoblastic leukaemia
- Angela Gutierrez-Camino
- , Chantal Richer
- & Daniel Sinnett
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Review Article |
Acquired copy number variation in prostate tumours: a review of common somatic copy number alterations, how they are formed and their clinical utility
- Dannielle E. O’Malley
- , Kelsie Raspin
- & Liesel M. FitzGerald
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Article |
Subclonal accumulation of immune escape mechanisms in microsatellite instability-high colorectal cancers
- Yuta Kobayashi
- , Atsushi Niida
- & Koshi Mimori
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Article
| Open AccessComputational textural mapping harmonises sampling variation and reveals multidimensional histopathological fingerprints
- Otso Brummer
- , Petri Pölönen
- & Oscar Brück
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Article
| Open AccessProbing the diabetes and colorectal cancer relationship using gene – environment interaction analyses
- Niki Dimou
- , Andre E. Kim
- & Ulrike Peters
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Review Article
| Open AccessReshaping the tumour immune microenvironment in solid tumours via tumour cell and immune cell DNA methylation: from mechanisms to therapeutics
- Fengyun Zhong
- , Yilin Lin
- & Zhanlong Shen
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Article
| Open AccessOvarian cancer pathology characteristics as predictors of variant pathogenicity in BRCA1 and BRCA2
- Denise G. O’Mahony
- , Susan J. Ramus
- & Elizabeth Santana dos Santos
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Article
| Open AccessSelective inhibition of HDAC6 promotes bladder cancer radiosensitization and mitigates the radiation-induced CXCL1 signalling
- Yu-Chieh Tsai
- , Tzu-Yin Wang
- & Sheng-Fang Su
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Article |
Exome sequencing of affected duos and trios uncovers PRUNE2 as a novel prostate cancer predisposition gene
- Marta Cardoso
- , Sofia Maia
- & Manuel R. Teixeira
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Article
| Open AccessClinical utility of liquid biopsy and integrative genomic profiling in early-stage and oligometastatic cancer patients treated with radiotherapy
- Guadalupe A. Cifuentes
- , Adrián Santiago
- & Rubén Cabanillas
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Correspondence
| Open AccessGenetic risk scores may compound rather than solve the issue of prostate cancer overdiagnosis
- Rachel H. Horton
- , Malcolm G. Dunlop
- & Amit Sud
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Article
| Open AccessDisentangling the aetiological pathways between body mass index and site-specific cancer risk using tissue-partitioned Mendelian randomisation
- Genevieve M. Leyden
- , Michael P. Greenwood
- & Tom G. Richardson
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Comment |
Age distribution and a multi-stage theory of carcinogenesis: 70 years on
- Anna Wilkins
- , Richard Corbett
- & Rosalind Eeles
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Article |
YTHDF2-mediated FGF14-AS2 decay promotes osteolytic metastasis of breast cancer by enhancing RUNX2 mRNA translation
- Ming Zhang
- , Jue Wang
- & Changyan Ma
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Article |
Clinical and genomic correlates of imatinib response in melanomas with KIT alterations
- Seungyeon Jung
- , Emma Armstrong
- & Douglas B. Johnson
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Review Article |
Is loss of p53 a driver of ductal carcinoma in situ progression?
- Rhiannon L. Morrissey
- , Alastair M. Thompson
- & Guillermina Lozano
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Article |
Predicted leukocyte telomere length and risk of germ cell tumours
- Shannon S. Cigan
- , John J. Meredith
- & Jenny N. Poynter
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Article
| Open AccessAnti-cancer therapy is associated with long-term epigenomic changes in childhood cancer survivors
- Natassia Robinson
- , John Casement
- & Gordon Strathdee
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Review Article
| Open AccessLiquid biopsies to monitor and direct cancer treatment in colorectal cancer
- Gianluca Mauri
- , Pietro Paolo Vitiello
- & Alberto Bardelli
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Article
| Open AccessCDH1 germline variants are enriched in patients with colorectal cancer, gastric cancer, and breast cancer
- Elio Adib
- , Talal El Zarif
- & Guru Sonpavde
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Article
| Open AccessImpact of KRAS, BRAF and microsatellite instability status after cytoreductive surgery and HIPEC in a national cohort of colorectal peritoneal metastasis patients
- S. G. Larsen
- , M. A. Goscinski
- & H. Sorbye
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Review Article
| Open AccessAt the dawn: cell-free DNA fragmentomics and gene regulation
- Yaping Liu
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Article |
The HOXB13 variant X285K is associated with clinical significance and early age at diagnosis in African American prostate cancer patients
- Rong Na
- , Jun Wei
- & William B. Isaacs
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Review Article
| Open AccessFunctional annotation of breast cancer risk loci: current progress and future directions
- Shirleny Romualdo Cardoso
- , Andrea Gillespie
- & Olivia Fletcher
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Article |
Identifying causality, genetic correlation, priority and pathways of large-scale complex exposures of breast and ovarian cancers
- Shucheng Si
- , Jiqing Li
- & Fuzhong Xue
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Article |
Multi-omics mapping of human papillomavirus integration sites illuminates novel cervical cancer target genes
- Marissa Iden
- , Shirng-Wern Tsaih
- & Janet S. Rader
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Article
| Open AccessWhole-genome sequencing facilitates patient-specific quantitative PCR-based minimal residual disease monitoring in acute lymphoblastic leukaemia, neuroblastoma and Ewing sarcoma
- Vinod Vijay Subhash
- , Libby Huang
- & Toby N. Trahair
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Review Article |
A wake-up call for cancer DNA damage: the role of Schlafen 11 (SLFN11) across multiple cancers
- Bingnan Zhang
- , Kavya Ramkumar
- & Lauren Averett Byers
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Article |
CEA, CA19-9, circulating DNA and circulating tumour cell kinetics in patients treated for metastatic colorectal cancer (mCRC)
- David Sefrioui
- , Ludivine Beaussire
- & Frédéric Di Fiore
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Review Article |
The breast is yet to come: current and future utility of circulating tumour DNA in breast cancer
- Brad A. Davidson
- , Sarah Croessmann
- & Ben H. Park
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Article |
Tandem histone methyltransferase upregulation defines a unique aggressive prostate cancer phenotype
- Mikolaj Filon
- , Joseph Gawdzik
- & David Jarrard
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Article |
Association between risk factors, molecular features and CpG island methylator phenotype colorectal cancer among different age groups in a Taiwanese cohort
- Kuo-Hsing Chen
- , Liang-In Lin
- & Kun-Huei Yeh
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Article |
Schlafen 11 predicts response to platinum-based chemotherapy in gastric cancers
- Tsuyoshi Takashima
- , Daiki Taniyama
- & Wataru Yasui
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Comment |
A bacterial mutational footprint in colorectal cancer genomes
- Axel Rosendahl Huber
- , Cayetano Pleguezuelos-Manzano
- & Jens Puschhof
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Article
| Open AccessA 10-gene prognostic signature points to LIMCH1 and HLA-DQB1 as important players in aggressive cervical cancer disease
- Mari K. Halle
- , Marte Sødal
- & Camilla Krakstad
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Article
| Open AccessHepatic metastasis of gastric cancer is associated with enhanced expression of ethanolamine kinase 2 via the p53–Bcl-2 intrinsic apoptosis pathway
- Takashi Miwa
- , Mitsuro Kanda
- & Yasuhiro Kodera
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Article
| Open AccessEpigenome-wide analysis reveals functional modulators of drug sensitivity and post-treatment survival in chronic lymphocytic leukaemia
- Timothy M. Barrow
- , Sirintra Nakjang
- & Gordon Strathdee
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Article
| Open AccessDroplet-digital PCR reveals frequent mutations in TERT promoter region in breast fibroadenomas and phyllodes tumours, irrespective of the presence of MED12 mutations
- Kazutaka Otsuji
- , Takeshi Sasaki
- & Yasuyuki Seto
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Article
| Open AccessLong noncoding RNA HOTAIR regulates the invasion and metastasis of prostate cancer by targeting hepaCAM
- Ting Li
- , Nanjing Liu
- & Xiaohou Wu
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Article
| Open AccessClinically and biologically relevant subgroups of Wilms tumour defined by genomic and epigenomic analyses
- Jack Brzezinski
- , Sanaa Choufani
- & Rosanna Weksberg
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Article
| Open AccessPopulation-scale predictions of DPD and TPMT phenotypes using a quantitative pharmacogene-specific ensemble classifier
- Yitian Zhou
- , Carolina Dagli Hernandez
- & Volker M. Lauschke
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Brief Communication
| Open AccessGermline HOXB13 G84E mutation carriers and risk to twenty common types of cancer: results from the UK Biobank
- Jun Wei
- , Zhuqing Shi
- & Jianfeng Xu
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Article
| Open AccessLongitudinal monitoring of circulating tumour DNA improves prognostication and relapse detection in gastroesophageal adenocarcinoma
- Mark R. Openshaw
- , Ali Abdulnabi Suwaidan
- & Jacqui A. Shaw
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Brief Communication
| Open AccessWhole-exome sequencing of long-term, never relapse exceptional responders of trastuzumab-treated HER2+ metastatic breast cancer
- Naomi Walsh
- , Charlotte Andrieu
- & John Crown
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Correspondence
| Open AccessComment on: “UGT2B17 modifies drug response in chronic lymphocytic leukaemia”
- Spyros I. Papamichos
- & Christof Jungbauer
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