Featured
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Article
| Open AccessHistological diagnosis of polyploidy discriminates an aggressive subset of hepatocellular carcinomas with poor prognosis
- Takanori Matsuura
- , Yoshihide Ueda
- & Tomonori Matsumoto
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Article
| Open AccessOvarian cancer pathology characteristics as predictors of variant pathogenicity in BRCA1 and BRCA2
- Denise G. O’Mahony
- , Susan J. Ramus
- & Elizabeth Santana dos Santos
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Article
| Open AccessClinical utility of liquid biopsy and integrative genomic profiling in early-stage and oligometastatic cancer patients treated with radiotherapy
- Guadalupe A. Cifuentes
- , Adrián Santiago
- & Rubén Cabanillas
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Correspondence |
Comment on: “Hypoxia differently modulates the release of mitochondrial and nuclear DNA”
- Boris K. L. Wong
- , Fan Zhang
- & Daniel R. A. Cox
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Article
| Open AccessDroplet-digital PCR reveals frequent mutations in TERT promoter region in breast fibroadenomas and phyllodes tumours, irrespective of the presence of MED12 mutations
- Kazutaka Otsuji
- , Takeshi Sasaki
- & Yasuyuki Seto
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Brief Communication
| Open AccessGermline HOXB13 G84E mutation carriers and risk to twenty common types of cancer: results from the UK Biobank
- Jun Wei
- , Zhuqing Shi
- & Jianfeng Xu
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Article
| Open AccessAddition of an online, validated family history questionnaire to the Dutch FIT-based screening programme did not improve its diagnostic yield
- Victorine H. Roos
- , Frank G. J. Kallenberg
- & Evelien Dekker
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Article
| Open AccessTumour mutation status and melanoma recurrence following a negative sentinel lymph node biopsy
- Nikki R. Adler
- , Rory Wolfe
- & Victoria J. Mar
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Article
| Open AccessMultivariable clinical-genetic risk model for predicting venous thromboembolic events in patients with cancer
- Andrés J. Muñoz Martín
- , Israel Ortega
- & Jose M. Soria
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Genetics and Genomics
| Open AccessClinically significant mutations in HIV-infected patients with lung adenocarcinoma
- Jonathan Thaler
- , Carlie Sigel
- & Keith Sigel
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Short Communication
| Open AccessFfar2 expression regulates leukaemic cell growth in vivo
- Laure B Bindels
- , Paolo E Porporato
- & Nathalie M Delzenne
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Genetics and Genomics
| Open AccessGNAQ and GNA11 mutations and downstream YAP activation in choroidal nevi
- M J C Vader
- , M C Madigan
- & P A van der Velden
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Genetics and Genomics
| Open AccessEvidence for genetic association between chromosome 1q loci and predisposition to colorectal neoplasia
- Stephanie A Schubert
- , Dina Ruano
- & Tom van Wezel
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Genetics and Genomics
| Open AccessClinical study of genomic drivers in pancreatic ductal adenocarcinoma
- Michael T Barrett
- , Ray Deiotte
- & Daniel D Von Hoff
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Genetics and Genomics
| Open AccessComprehensive analysis of copy number aberrations in microsatellite stable colon cancer in view of stromal component
- M Henar Alonso
- , Susanna Aussó
- & Victor Moreno
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Clinical Study
| Open AccessThe role of primary tumour sidedness, EGFR gene copy number and EGFR promoter methylation in RAS/BRAF wild-type colorectal cancer patients receiving irinotecan/cetuximab
- Laura Demurtas
- , Marco Puzzoni
- & Mario Scartozzi
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Genetics and Genomics
| Open AccessA meta-analysis of CXCL12 expression for cancer prognosis
- Harsh Samarendra
- , Keaton Jones
- & Alex Gordon-Weeks
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Molecular Diagnostics
| Open AccessMutation status among patients with sinonasal mucosal melanoma and its impact on survival
- Moran Amit
- , Samantha Tam
- & Ehab Y Hanna
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Genetics and Genomics
| Open AccessThe spectrum of EWSR1-rearranged neoplasms at a tertiary sarcoma centre; assessing 772 tumour specimens and the value of current ancillary molecular diagnostic modalities
- Jonathan Noujaim
- , Robin L Jones
- & Khin Thway
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Molecular Diagnostics
| Open AccessComparative mutational landscape analysis of patient-derived tumour xenografts
- Mariana Brait
- , Evgeny Izumchenko
- & David Sidransky
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Review
| Open AccessTissue-based next generation sequencing: application in a universal healthcare system
- Seán O Hynes
- , Brendan Pang
- & Manuel Salto-Tellez
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Letter to the Editor
| Open AccessComment on ‘The incidence of leukaemia in women with BRCA1 and BRCA2 mutations: an International Prospective Cohort Study’
- Bernard Friedenson
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Genetics and Genomics
| Open AccessCommon genetic variation associated with increased susceptibility to prostate cancer does not increase risk of radiotherapy toxicity
- Mahbubl Ahmed
- , Leila Dorling
- & Catharine M L West
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Genetics and Genomics
| Open AccessThe incidence of leukaemia in women with BRCA1 and BRCA2 mutations: an International Prospective Cohort Study
- Javaid Iqbal
- , Andre Nussenzweig
- & Ophira Ginsburg
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Genetics and Genomics
| Open AccessHypermethylation of genes in testicular embryonal carcinomas
- Hoi-Hung Cheung
- , Yanzhou Yang
- & Wai-Yee Chan
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Molecular Diagnostics
| Open AccessPTEN loss in circulating tumour cells correlates with PTEN loss in fresh tumour tissue from castration-resistant prostate cancer patients
- Elizabeth A Punnoose
- , Roberta Ferraldeschi
- & Johann de Bono
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Molecular Diagnostics
| Open AccessIdentification of a hypoxia-regulated miRNA signature in bladder cancer and a role for miR-145 in hypoxia-dependent apoptosis
- C Blick
- , A Ramachandran
- & A L Harris
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Translational Therapeutics
| Open AccessGene therapy with SOCS1 for gastric cancer induces G2/M arrest and has an antitumour effect on peritoneal carcinomatosis
- Rie Natatsuka
- , Tsuyoshi Takahashi
- & Tetsuji Naka
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Molecular Diagnostics
| Open AccessSerum LAMC2 enhances the prognostic value of a multi-parametric panel in non-small cell lung cancer
- D Korbakis
- , A Dimitromanolakis
- & E P Diamandis
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Review
| Open AccessClinical utility of RASSF1A methylation in human malignancies
- A M Grawenda
- & E O'Neill
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Molecular Diagnostics
| Open AccessOverexpression of connexin 43 reduces melanoma proliferative and metastatic capacity
- A Tittarelli
- , I Guerrero
- & F Salazar-Onfray
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Molecular Diagnostics
| Open AccessmiR-9-3p plays a tumour-suppressor role by targeting TAZ (WWTR1) in hepatocellular carcinoma cells
- T Higashi
- , H Hayashi
- & H Baba
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Short Communication
| Open AccessPersonal history of rosacea and risk of incident cancer among women in the US
- W-Q Li
- , M Zhang
- & A A Qureshi
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Genetics and Genomics
| Open AccessMC1R gene variants and non-melanoma skin cancer: a pooled-analysis from the M-SKIP project
- E Tagliabue
- , M C Fargnoli
- & S Raimondi
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Molecular Diagnostics
| Open AccessThe expression of tumour suppressors and proto-oncogenes in tissues susceptible to their hereditary cancers
- Brian Muir
- & Leonard Nunney
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Molecular Diagnostics
| Open AccessMicrosatellite instable vs stable colon carcinomas: analysis of tumour heterogeneity, inflammation and angiogenesis
- L De Smedt
- , J Lemahieu
- & X Sagaert
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Epidemiology
| Open AccessAn analysis of the association between prostate cancer risk loci, PSA levels, disease aggressiveness and disease-specific mortality
- J Sullivan
- , R Kopp
- & R J Klein
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Molecular Diagnostics
| Open AccessSNPs at miR-155 binding sites of TYRP1 explain discrepancy between mRNA and protein and refine TYRP1 prognostic value in melanoma
- P El Hajj
- , D Gilot
- & F Journe
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Molecular Diagnostics
| Open AccessExosomal microRNA in serum is a novel biomarker of recurrence in human colorectal cancer
- T Matsumura
- , K Sugimachi
- & K Mimori
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Molecular Diagnostics
| Open AccessThe von Hippel–Lindau tumour suppressor gene: uncovering the expression of the pVHL172 isoform
- F Chesnel
- , P Hascoet
- & Y Arlot-Bonnemains
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Molecular Diagnostics
| Open AccessMiR-320e is a novel prognostic biomarker in colorectal cancer
- L Perez-Carbonell
- , F A Sinicrope
- & A Goel
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Clinical Study
| Open AccessPhase I study of FOLFIRI plus pimasertib as second-line treatment for KRAS-mutated metastatic colorectal cancer
- T Macarulla
- , A Cervantes
- & F Ciardiello
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Genetics and Genomics
| Open AccessCombination of microsatellite instability and BRAF mutation status for subtyping colorectal cancer
- T T Seppälä
- , J P Böhm
- & J-P Mecklin
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Translational Therapeutics
| Open AccessMicroRNA-224 is associated with colorectal cancer progression and response to 5-fluorouracil-based chemotherapy by KRAS-dependent and -independent mechanisms
- E B Amankwatia
- , P Chakravarty
- & G Smith
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Genetics and Genomics
| Open AccessEconomic evaluation of DNA ploidy analysis vs liquid-based cytology for cervical screening
- V T Nghiem
- , K R Davies
- & S B Cantor
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Full Paper
| Open AccessCirculating cell-free AR and CYP17A1 copy number variations may associate with outcome of metastatic castration-resistant prostate cancer patients treated with abiraterone
- S Salvi
- , V Casadio
- & U De Giorgi
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Molecular Diagnostics
| Open AccessCancer spectrum and frequency among children with Noonan, Costello, and cardio-facio-cutaneous syndromes
- C P Kratz
- , L Franke
- & M Zenker