Microbiology

Definition

Microbiology is the study of microscopic organisms, such as bacteria, viruses, archaea, fungi and protozoa. This discipline includes fundamental research on the biochemistry, physiology, cell biology, ecology, evolution and clinical aspects of microorganisms, including the host response to these agents.

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Latest Research and Reviews

News and Comment

  • Editorial |

    Despite major advances in dissecting how pathogens cause disease and the development of treatments to combat infection, infectious diseases remain a major cause of death today. This month’s issue includes a special ‘Focus on Infectious Disease’, which highlights efforts to develop new ways to prevent, detect and treat infections.

  • News and Views |

    Hydrolysis of phosphatidylcholine to choline was found to be catalysed by phospholipase D enzymes from diverse members of the gut microbiota, revealing a mechanism by which commensals obtain choline for subsequent production of disease-associated trimethylamine.

    • Aaron T. Wright
  • News and Views |

    APOBEC3 restriction, known to inhibit retroviruses by interfering with genome replication and hypermutating viral DNA, targets the γ-herpesvirus Epstein–Barr virus and is antagonized by the viral BORF2 protein.

    • Michael H. Malim
    •  & Darja Pollpeter
  • News and Views |

    The early identification of repetitive genomic loci in Haloferax species was instrumental in igniting interest in CRISPR–Cas systems. Now, work in this genus has revealed an important role of CRISPR–Cas in reducing an unusual form of inter-species archaeal mating that occurs by cell fusion.

    • Peter C. Fineran