Specially commissioned Reviews and a Perspective provide a guide to the maturing field of single-molecule analysis and two original research papers describe complementary advances in nanoscale visualization.
Focus on Single-Molecule Analysis Do-it-yourself guide: how to use the modern single-molecule toolkitpp475 - 489 Nils G Walter, Cheng-Yen Huang, Anthony J Manzo & Mohamed A Sobhy Published online: 29 May 2008|doi:10.1038/nmeth.1215 Abstract|Full text|PDF
(848K)
Focus on Single-Molecule Analysis Single-molecule force spectroscopy: optical tweezers, magnetic tweezers and atomic force microscopypp491 - 505 Keir C Neuman & Attila Nagy Published online: 29 May 2008|doi:10.1038/nmeth.1218 Abstract|Full text|PDF
(1,500K)
Focus on Single-Molecule Analysis A practical guide to single-molecule FRETpp507 - 516 Rahul Roy, Sungchul Hohng & Taekjip Ha Published online: 29 May 2008|doi:10.1038/nmeth.1208 Abstract|Full text|PDF
(702K)
|Supplementary Information
Focus on Single-Molecule Analysis Laminar flow cells for single-molecule studies of DNA-protein interactionspp517 - 525 Laurence R Brewer & Piero R Bianco Published online: 29 May 2008|doi:10.1038/nmeth.1217 Abstract|Full text|PDF
(607K)
|Supplementary Information
Focus on Single-Molecule Analysis Three-dimensional sub–100 nm resolution fluorescence microscopy of thick samplespp527 - 529 Manuel F Juette, Travis J Gould, Mark D Lessard, Michael J Mlodzianoski, Bhupendra S Nagpure, Brian T Bennett, Samuel T Hess & Joerg Bewersdorf Published online: 11 May 2008|doi:10.1038/nmeth.1211 Abstract|Full text|PDF
(471K)
|Supplementary Information See also:News and Views by Shaevitz
Focus on Single-Molecule Analysis Spherical nanosized focal spot unravels the interior of cellspp539 - 544 Roman Schmidt, Christian A Wurm, Stefan Jakobs, Johann Engelhardt, Alexander Egner & Stefan W Hell Published online: 18 May 2008|doi:10.1038/nmeth.1214 Abstract|Full text|PDF
(365K)
|Supplementary Information See also:News and Views by Shaevitz
