This focus presents the first formal results of the MicroArray Quality Control (MAQC) project, an unprecedented, community-wide effort, under the auspices of the FDA, with the goal of experimentally addressing the key issues surrounding the reliability of DNA microarray data and establishing operational metrics to objectively assess the performance of seven microarray platforms. Ultimately, it is hoped that the MAQC effort will provide the research and regulatory communities with a foundation from which to derive the necessary guidelines for using microarrays in clinical practice and regulatory decision-making.
Microarray Quality Control Empowering microarrays in the regulatory settingp1103 Daniel A. Casciano & Janet Woodcock doi:10.1038/nbt0906-1103 Full text|PDF
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Microarray Quality Control Impact of microarray data quality on genomic data submissions to the FDApp1105 - 1107 Felix W Frueh doi:10.1038/nbt0906-1105 Abstract|Full text|PDF
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Microarray Quality Control A framework for the use of genomics data at the EPApp1108 - 1111 David J Dix, Kathryn Gallagher, William H Benson, Brenda L Groskinsky, J Thomas McClintock, Kerry L Dearfield & William H Farland doi:10.1038/nbt0906-1108 Abstract|Full text|PDF
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Microarray Quality Control Data quality in genomics and microarrayspp1112 - 1113 Hanlee Ji & Ronald W Davis doi:10.1038/nbt0906-1112 Abstract|Full text|PDF
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Microarray Quality Control Evaluation of DNA microarray results with quantitative gene expression platformspp1115 - 1122 Roger D Canales, Yuling Luo, James C Willey, Bradley Austermiller, Catalin C Barbacioru, Cecilie Boysen, Kathryn Hunkapiller, Roderick V Jensen, Charles R Knight, Kathleen Y Lee, Yunqing Ma, Botoul Maqsodi, Adam Papallo, Elizabeth Herness Peters, Karen Poulter, Patricia L Ruppel, Raymond R Samaha, Leming Shi, Wen Yang, Lu Zhang & Federico M Goodsaid Published online: 08 September 2006|doi:10.1038/nbt1236 Abstract|Full text|PDF
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Microarray Quality Control Using RNA sample titrations to assess microarray platform performance and normalization techniquespp1123 - 1131 Richard Shippy, Stephanie Fulmer-Smentek, Roderick V Jensen, Wendell D Jones, Paul K Wolber, Charles D Johnson, P Scott Pine, Cecilie Boysen, Xu Guo, Eugene Chudin, Yongming Andrew Sun, James C Willey, Jean Thierry-Mieg, Danielle Thierry-Mieg, Robert A Setterquist, Mike Wilson, Anne Bergstrom Lucas, Natalia Novoradovskaya, Adam Papallo, Yaron Turpaz, Shawn C Baker, Janet A Warrington, Leming Shi & Damir Herman Published online: 08 September 2006|doi:10.1038/nbt1241 Abstract|Full text|PDF
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Microarray Quality Control Evaluation of external RNA controls for the assessment of microarray performancepp1132 - 1139 Weida Tong, Anne Bergstrom Lucas, Richard Shippy, Xiaohui Fan, Hong Fang, Huixiao Hong, Michael S Orr, Tzu-Ming Chu, Xu Guo, Patrick J Collins, Yongming Andrew Sun, Sue-Jane Wang, Wenjun Bao, Russell D Wolfinger, Svetlana Shchegrova, Lei Guo, Janet A Warrington & Leming Shi Published online: 09 August 2006|doi:10.1038/nbt1237 Abstract|Full text|PDF
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Microarray Quality Control Performance comparison of one-color and two-color platforms within the Microarray Quality Control (MAQC) projectpp1140 - 1150 Tucker A Patterson, Edward K Lobenhofer, Stephanie B Fulmer-Smentek, Patrick J Collins, Tzu-Ming Chu, Wenjun Bao, Hong Fang, Ernest S Kawasaki, Janet Hager, Irina R Tikhonova, Stephen J Walker, Liang Zhang, Patrick Hurban, Francoise de Longueville, James C Fuscoe, Weida Tong, Leming Shi & Russell D Wolfinger Published online: 08 September 2006|doi:10.1038/nbt1242 Abstract|Full text|PDF
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Articles
Microarray Quality Control The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurementspp1151 - 1161 MAQC Consortium (Leming Shi, Laura H Reid, Wendell D Jones, Richard Shippy, Janet A Warrington, Shawn C Baker, Patrick J Collins, Francoise de Longueville, Ernest S Kawasaki, Kathleen Y Lee, Yuling Luo, Yongming Andrew Sun, James C Willey, Robert A Setterquist, Gavin M Fischer, Weida Tong, Yvonne P Dragan, David J Dix, Felix W Frueh, Federico M Goodsaid, Damir Herman, Roderick V Jensen, Charles D Johnson, Edward K Lobenhofer, Raj K Puri, Uwe Scherf, Jean Thierry-Mieg, Charles Wang, Mike Wilson, Paul K Wolber, Lu Zhang, Shashi Amur, Wenjun Bao, Catalin C Barbacioru, Anne Bergstrom Lucas, Vincent Bertholet, Cecilie Boysen, Bud Bromley, Donna Brown, Alan Brunner, Roger Canales, Xiaoxi Megan Cao, Thomas A Cebula, James J Chen, Jing Cheng, Tzu-Ming Chu, Eugene Chudin, John Corson, J Christopher Corton, Lisa J Croner, Christopher Davies, Timothy S Davison, Glenda Delenstarr, Xutao Deng, David Dorris, Aron C Eklund, Xiao-hui Fan, Hong Fang, Stephanie Fulmer-Smentek, James C Fuscoe, Kathryn Gallagher, Weigong Ge, Lei Guo, Xu Guo, Janet Hager, Paul K Haje, Jing Han, Tao Han, Heather C Harbottle, Stephen C Harris, Eli Hatchwell, Craig A Hauser, Susan Hester, Huixiao Hong, Patrick Hurban, Scott A Jackson, Hanlee Ji, Charles R Knight, Winston P Kuo, J Eugene LeClerc, Shawn Levy, Quan-Zhen Li, Chunmei Liu, Ying Liu, Michael J Lombardi, Yunqing Ma, Scott R Magnuson, Botoul Maqsodi, Tim McDaniel, Nan Mei, Ola Myklebost, Baitang Ning, Natalia Novoradovskaya, Michael S Orr, Terry W Osborn, Adam Papallo, Tucker A Patterson, Roger G Perkins, Elizabeth H Peters, Ron Peterson, Kenneth L Philips, P Scott Pine, Lajos Pusztai, Feng Qian, Hongzu Ren, Mitch Rosen, Barry A Rosenzweig, Raymond R Samaha, Mark Schena, Gary P Schroth, Svetlana Shchegrova, Dave D Smith, Frank Staedtler, Zhenqiang Su, Hongmei Sun, Zoltan Szallasi, Zivana Tezak, Danielle Thierry-Mieg, Karol L Thompson, Irina Tikhonova, Yaron Turpaz, Beena Vallanat, Christophe Van, Stephen J Walker, Sue Jane Wang, Yonghong Wang, Russ Wolfinger, Alex Wong, Jie Wu, Chunlin Xiao, Qian Xie, Jun Xu, Wen Yang, Liang Zhang, Sheng Zhong, Yaping Zong & William Slikker Jr) Published online: 08 September 2006|doi:10.1038/nbt1239 Abstract|Full text|PDF
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Microarray Quality Control Rat toxicogenomic study reveals analytical consistency across microarray platformspp1162 - 1169 Lei Guo, Edward K Lobenhofer, Charles Wang, Richard Shippy, Stephen C Harris, Lu Zhang, Nan Mei, Tao Chen, Damir Herman, Federico M Goodsaid, Patrick Hurban, Kenneth L Phillips, Jun Xu, Xutao Deng, Yongming Andrew Sun, Weida Tong, Yvonne P Dragan & Leming Shi Published online: 08 September 2006|doi:10.1038/nbt1238 Abstract|Full text|PDF
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