Nature Biotechnology
- 24, 1162 - 1169 (2006)
Published online: 8 September 2006; | doi:10.1038/nbt1238
Rat toxicogenomic study reveals analytical consistency across microarray platformsLei Guo, Edward K Lobenhofer, Charles Wang, Richard Shippy, Stephen C Harris, Lu Zhang, Nan Mei, Tao Chen, Damir Herman, Federico M Goodsaid, Patrick Hurban, Kenneth L Phillips, Jun Xu, Xutao Deng, Yongming Andrew Sun, Weida Tong, Yvonne P Dragan & Leming Shi Supplementary Fig. 1 (pdf 204K) Principal component analysis of the platform-specific microarray data separates samples by tissue and treatment. Supplementary Fig. 2 (pdf 400K) Inter-site overlap of differentially expressed gene lists generated using different selection criteria. Supplementary Fig. 3 (pdf 32K) Overlap of differentially expressed gene lists between different normalization methods. Supplementary Fig. 4 (pdf 100K) Inter-site concordance of lists of differentially expressed genes based on fold-change, t-statistic, SAM, and random selection. Supplementary Fig. 5 (pdf 1M) Cross-platform overlap of differentially expressed gene lists generated using different selection criteria. Supplementary Table 1 (xls 36K) Summary of RNA Sample Information. Supplementary Table 2 (xls 1M) Cross-Platform Probe Sequence Mapping (5,112 commonly mapped rat genes).
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