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Microarray Quality Control
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Nature Biotechnology - 24, 1162 - 1169 (2006)
Published online: 8 September 2006; | doi:10.1038/nbt1238

Rat toxicogenomic study reveals analytical consistency across microarray platforms

Lei Guo, Edward K Lobenhofer, Charles Wang, Richard Shippy, Stephen C Harris, Lu Zhang, Nan Mei, Tao Chen, Damir Herman, Federico M Goodsaid, Patrick Hurban, Kenneth L Phillips, Jun Xu, Xutao Deng, Yongming Andrew Sun, Weida Tong, Yvonne P Dragan & Leming Shi

Supplementary Fig. 1 (pdf 204K)
Principal component analysis of the platform-specific microarray data separates samples by tissue and treatment.

Supplementary Fig. 2 (pdf 400K)
Inter-site overlap of differentially expressed gene lists generated using different selection criteria.

Supplementary Fig. 3 (pdf 32K)
Overlap of differentially expressed gene lists between different normalization methods.

Supplementary Fig. 4 (pdf 100K)
Inter-site concordance of lists of differentially expressed genes based on fold-change, t-statistic, SAM, and random selection.

Supplementary Fig. 5 (pdf 1M)
Cross-platform overlap of differentially expressed gene lists generated using different selection criteria.

Supplementary Table 1 (xls 36K)
Summary of RNA Sample Information.

Supplementary Table 2 (xls 1M)
Cross-Platform Probe Sequence Mapping (5,112 commonly mapped rat genes).


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Nature Biotechnology
ISSN: 1087-0156
EISSN: 1546-1696
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