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Focus
 
Microarray Quality Control
  Contents     Editorial   Commentary
Research Glossary Feedback
This focus presents the first formal results of the MicroArray Quality Control (MAQC) project, an unprecedented, community-wide effort, under the auspices of the FDA, with the goal of experimentally addressing the key issues surrounding the reliability of DNA microarray data and establishing operational metrics to objectively assess the performance of seven microarray platforms. Ultimately, it is hoped that the MAQC effort will provide the research and regulatory communities with a foundation from which to derive the necessary guidelines for using microarrays in clinical practice and regulatory decision-making.
Editorial Top
Microarray Quality Control
Making the most of microarrays p1039
doi:10.1038/nbt0906-1039
Abstract | Full text | PDF (80K)
Foreword Top
Microarray Quality Control
Empowering microarrays in the regulatory setting p1103
Daniel A. Casciano & Janet Woodcock
doi:10.1038/nbt0906-1103
Full text | PDF (56K)
Opinion and Comment Top
Commentary
Microarray Quality Control
Impact of microarray data quality on genomic data submissions to the FDA pp1105 - 1107
Felix W Frueh
doi:10.1038/nbt0906-1105
Abstract | Full text | PDF (105K)
Microarray Quality Control
A framework for the use of genomics data at the EPA pp1108 - 1111
David J Dix, Kathryn Gallagher, William H Benson, Brenda L Groskinsky, J Thomas McClintock, Kerry L Dearfield & William H Farland
doi:10.1038/nbt0906-1108
Abstract | Full text | PDF (234K)
Microarray Quality Control
Data quality in genomics and microarrays pp1112 - 1113
Hanlee Ji & Ronald W Davis
doi:10.1038/nbt0906-1112
Abstract | Full text | PDF (227K)
Research Top
Analysis
Microarray Quality Control
Evaluation of DNA microarray results with quantitative gene expression platforms pp1115 - 1122
Roger D Canales, Yuling Luo, James C Willey, Bradley Austermiller, Catalin C Barbacioru, Cecilie Boysen, Kathryn Hunkapiller, Roderick V Jensen, Charles R Knight, Kathleen Y Lee, Yunqing Ma, Botoul Maqsodi, Adam Papallo, Elizabeth Herness Peters, Karen Poulter, Patricia L Ruppel, Raymond R Samaha, Leming Shi, Wen Yang, Lu Zhang & Federico M Goodsaid
Published online: 08 September 2006 | doi:10.1038/nbt1236
Abstract | Full text | PDF (1,459K)  | Supplementary Information
Microarray Quality Control
Using RNA sample titrations to assess microarray platform performance and normalization techniques pp1123 - 1131
Richard Shippy, Stephanie Fulmer-Smentek, Roderick V Jensen, Wendell D Jones, Paul K Wolber, Charles D Johnson, P Scott Pine, Cecilie Boysen, Xu Guo, Eugene Chudin, Yongming Andrew Sun, James C Willey, Jean Thierry-Mieg, Danielle Thierry-Mieg, Robert A Setterquist, Mike Wilson, Anne Bergstrom Lucas, Natalia Novoradovskaya, Adam Papallo, Yaron Turpaz, Shawn C Baker, Janet A Warrington, Leming Shi & Damir Herman
Published online: 08 September 2006 | doi:10.1038/nbt1241
Abstract | Full text | PDF (1,946K)  | Supplementary Information
Microarray Quality Control
Evaluation of external RNA controls for the assessment of microarray performance pp1132 - 1139
Weida Tong, Anne Bergstrom Lucas, Richard Shippy, Xiaohui Fan, Hong Fang, Huixiao Hong, Michael S Orr, Tzu-Ming Chu, Xu Guo, Patrick J Collins, Yongming Andrew Sun, Sue-Jane Wang, Wenjun Bao, Russell D Wolfinger, Svetlana Shchegrova, Lei Guo, Janet A Warrington & Leming Shi
Published online: 09 August 2006 | doi:10.1038/nbt1237
Abstract | Full text | PDF (2,378K)  | Supplementary Information
Microarray Quality Control
Performance comparison of one-color and two-color platforms within the Microarray Quality Control (MAQC) project pp1140 - 1150
Tucker A Patterson, Edward K Lobenhofer, Stephanie B Fulmer-Smentek, Patrick J Collins, Tzu-Ming Chu, Wenjun Bao, Hong Fang, Ernest S Kawasaki, Janet Hager, Irina R Tikhonova, Stephen J Walker, Liang Zhang, Patrick Hurban, Francoise de Longueville, James C Fuscoe, Weida Tong, Leming Shi & Russell D Wolfinger
Published online: 08 September 2006 | doi:10.1038/nbt1242
Abstract | Full text | PDF (3,845K)  | Supplementary Information
Articles
Microarray Quality Control
The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements pp1151 - 1161
MAQC Consortium (Leming Shi, Laura H Reid, Wendell D Jones, Richard Shippy, Janet A Warrington, Shawn C Baker, Patrick J Collins, Francoise de Longueville, Ernest S Kawasaki, Kathleen Y Lee, Yuling Luo, Yongming Andrew Sun, James C Willey, Robert A Setterquist, Gavin M Fischer, Weida Tong, Yvonne P Dragan, David J Dix, Felix W Frueh, Federico M Goodsaid, Damir Herman, Roderick V Jensen, Charles D Johnson, Edward K Lobenhofer, Raj K Puri, Uwe Scherf, Jean Thierry-Mieg, Charles Wang, Mike Wilson, Paul K Wolber, Lu Zhang, Shashi Amur, Wenjun Bao, Catalin C Barbacioru, Anne Bergstrom Lucas, Vincent Bertholet, Cecilie Boysen, Bud Bromley, Donna Brown, Alan Brunner, Roger Canales, Xiaoxi Megan Cao, Thomas A Cebula, James J Chen, Jing Cheng, Tzu-Ming Chu, Eugene Chudin, John Corson, J Christopher Corton, Lisa J Croner, Christopher Davies, Timothy S Davison, Glenda Delenstarr, Xutao Deng, David Dorris, Aron C Eklund, Xiao-hui Fan, Hong Fang, Stephanie Fulmer-Smentek, James C Fuscoe, Kathryn Gallagher, Weigong Ge, Lei Guo, Xu Guo, Janet Hager, Paul K Haje, Jing Han, Tao Han, Heather C Harbottle, Stephen C Harris, Eli Hatchwell, Craig A Hauser, Susan Hester, Huixiao Hong, Patrick Hurban, Scott A Jackson, Hanlee Ji, Charles R Knight, Winston P Kuo, J Eugene LeClerc, Shawn Levy, Quan-Zhen Li, Chunmei Liu, Ying Liu, Michael J Lombardi, Yunqing Ma, Scott R Magnuson, Botoul Maqsodi, Tim McDaniel, Nan Mei, Ola Myklebost, Baitang Ning, Natalia Novoradovskaya, Michael S Orr, Terry W Osborn, Adam Papallo, Tucker A Patterson, Roger G Perkins, Elizabeth H Peters, Ron Peterson, Kenneth L Philips, P Scott Pine, Lajos Pusztai, Feng Qian, Hongzu Ren, Mitch Rosen, Barry A Rosenzweig, Raymond R Samaha, Mark Schena, Gary P Schroth, Svetlana Shchegrova, Dave D Smith, Frank Staedtler, Zhenqiang Su, Hongmei Sun, Zoltan Szallasi, Zivana Tezak, Danielle Thierry-Mieg, Karol L Thompson, Irina Tikhonova, Yaron Turpaz, Beena Vallanat, Christophe Van, Stephen J Walker, Sue Jane Wang, Yonghong Wang, Russ Wolfinger, Alex Wong, Jie Wu, Chunlin Xiao, Qian Xie, Jun Xu, Wen Yang, Liang Zhang, Sheng Zhong, Yaping Zong & William Slikker Jr)
Published online: 08 September 2006 | doi:10.1038/nbt1239
Abstract | Full text | PDF (419K)  | Supplementary Information
Microarray Quality Control
Rat toxicogenomic study reveals analytical consistency across microarray platforms pp1162 - 1169
Lei Guo, Edward K Lobenhofer, Charles Wang, Richard Shippy, Stephen C Harris, Lu Zhang, Nan Mei, Tao Chen, Damir Herman, Federico M Goodsaid, Patrick Hurban, Kenneth L Phillips, Jun Xu, Xutao Deng, Yongming Andrew Sun, Weida Tong, Yvonne P Dragan & Leming Shi
Published online: 08 September 2006 | doi:10.1038/nbt1238
Abstract | Full text | PDF (534K)  | Supplementary Information
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