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| Open AccessPANTHER: AZD8931, inhibitor of EGFR, ERBB2 and ERBB3 signalling, combined with FOLFIRI: a Phase I/II study to determine the importance of schedule and activity in colorectal cancer
- David J. Propper
- , Fangfei Gao
- & Daniel Hochhauser
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Age alone is not a barrier to efficacy of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for colorectal peritoneal metastases: analysis of 1138 patients from the UK and Ireland Colorectal Peritoneal Metastases Registry
- Michael E. Kelly
- , Niall J. O’Sullivan
- & Jonathan Wild
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| Open AccessThe utility of ctDNA in detecting minimal residual disease following curative surgery in colorectal cancer: a systematic review and meta-analysis
- Lucy G. Faulkner
- , Lynne M. Howells
- & Anne L. Thomas
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Targeted exome-based predictors of patterns of progression of colorectal liver metastasis after percutaneous thermal ablation
- Iwan Paolucci
- , Yuan-Mao Lin
- & Bruno C. Odisio
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Novel prognostic implications of complement activation in the tumour microenvironment for de novo metastatic BRAF V600E mutant colorectal cancer
- Kuo-Hsing Chen
- , Chia-Lang Hsu
- & Kun-Huei Yeh
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Article
| Open AccessEarly radiologic signal of responsiveness to immune checkpoint blockade in microsatellite-stable/mismatch repair-proficient metastatic colorectal cancer
- Sebastian Meltzer
- , Anne Negård
- & Anne Hansen Ree
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Review Article
| Open AccessRole of AI and digital pathology for colorectal immuno-oncology
- Mohsin Bilal
- , Mohammed Nimir
- & Nasir Rajpoot
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Long-term use of antihypertensive medications, hypertension and colorectal cancer risk and mortality: a prospective cohort study
- Yin Zhang
- , Mingyang Song
- & Edward L. Giovannucci
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Somatic hits in mismatch repair genes in colorectal cancer among non-seminoma testicular cancer survivors
- Berbel L. M. Ykema
- , Emilie C. H. Breekveldt
- & Monique E. van Leerdam
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Article
| Open AccessImpact of changes to the interscreening interval and faecal immunochemical test threshold in the national bowel cancer screening programme in England: results from the FIT pilot study
- Shuping J. Li
- , Tara Seedher
- & Stephen W. Duffy
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Neuropeptide Y, a paracrine factor secreted by cancer cells, is an independent regulator of angiogenesis in colon cancer
- Debanjan Chakroborty
- , Sandeep Goswami
- & Chandrani Sarkar
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| Open AccesspT3 colorectal cancer revisited: a multicentric study on the histological depth of invasion in more than 1000 pT3 carcinomas—proposal for a new pT3a/pT3b subclassification
- Sebastian Foersch
- , Corinna Lang-Schwarz
- & Moritz Jesinghaus
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Review Article
| Open AccessNon-aspirin non-steroidal anti-inflammatory drugs in colorectal cancer: a review of clinical studies
- Farzana Y. Zaman
- , Suzanne G. Orchard
- & John R. Zalcberg
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Modulation of autophagy: a Phase II study of vorinostat plus hydroxychloroquine versus regorafenib in chemotherapy-refractory metastatic colorectal cancer (mCRC)
- Sukeshi Patel Arora
- , Laura Tenner
- & Devalingam Mahalingam
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Clinicopathological and molecular characteristics of RSPO fusion-positive colorectal cancer
- Taiki Hashimoto
- , Daisuke Takayanagi
- & Shigeki Sekine
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Correspondence |
Comment on “Development and validation of a novel strong prognostic index for colon cancer through a robust combination of laboratory features for systemic inflammation: a prognostic immune nutritional index”
- Hailun Xie
- , Yizhong Ge
- & Hanping Shi
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Correspondence |
Reply to comment(s) on “Development and validation of a novel strong prognostic index for colon cancer through a robust combination of laboratory features for systemic inflammation: a prognostic immune nutritional index”
- Sang-Hyuk Jung
- , Dokyoon Kim
- & Ji Won Park
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| Open AccessEfficacy of FOLFIRI plus cetuximab vs FOLFIRI plus bevacizumab in 1st-line treatment of older patients with RAS wild-type metastatic colorectal cancer: an analysis of the randomised trial FIRE-3
- Laura E. Fischer
- , Sebastian Stintzing
- & Volker Heinemann
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Dynamic changes in longitudinal circulating tumour DNA profile during metastatic colorectal cancer treatment
- Sheehyun Kim
- , Yoojoo Lim
- & Tae-You Kim
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| Open AccessResectability, conversion, metastasectomy and outcome according to RAS and BRAF status for metastatic colorectal cancer in the prospective RAXO study
- Aki Uutela
- , Emerik Osterlund
- & Pia Osterlund
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Article
| Open AccessTXN inhibitor impedes radioresistance of colorectal cancer cells with decreased ALDH1L2 expression via TXN/NF-κB signaling pathway
- Lu Yu
- , Qiqing Guo
- & Yaowei Zhang
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Article
| Open AccessCalcium-binding protein S100P is a new target gene of MACC1, drives colorectal cancer metastasis and serves as a prognostic biomarker
- Felicitas Schmid
- , Mathias Dahlmann
- & Ulrike Stein
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| Open AccessPrognostic significance of spatial and density analysis of T lymphocytes in colorectal cancer
- Hanna Elomaa
- , Maarit Ahtiainen
- & Juha P. Väyrynen
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| Open AccessFirst-line trifluridine/tipiracil + bevacizumab in patients with unresectable metastatic colorectal cancer: final survival analysis in the TASCO1 study
- E. Van Cutsem
- , I. Danielewicz
- & V. Moiseyenko
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Circulating tumour DNA and its clinical utility in predicting treatment response or survival in patients with metastatic colorectal cancer: a systematic review and meta-analysis
- Louise B. Callesen
- , Julian Hamfjord
- & Karen-Lise G. Spindler
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A new magnetic resonance imaging tumour response grading scheme for locally advanced rectal cancer
- Xiaolin Pang
- , Peiyi Xie
- & Xiangbo Wan
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| Open AccessMRI radiomics independent of clinical baseline characteristics and neoadjuvant treatment modalities predicts response to neoadjuvant therapy in rectal cancer
- Maxiaowei Song
- , Shuai Li
- & Weihu Wang
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Aryl-hydrocarbon receptor-interacting protein regulates tumorigenic and metastatic properties of colorectal cancer cells driving liver metastasis
- Guillermo Solís-Fernández
- , Ana Montero-Calle
- & Rodrigo Barderas
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Article
| Open AccessFibroblast activation protein identifies Consensus Molecular Subtype 4 in colorectal cancer and allows its detection by 68Ga-FAPI-PET imaging
- Esther Strating
- , Emma Wassenaar
- & Onno Kranenburg
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Editorial |
Editorial on “A systematic review of microbial markers for risk prediction of colorectal neoplasia” by Yu and coauthors
- Maikel P. Peppelenbosch
- & Vincent T. Janmaat
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Mutational signature profiling classifies subtypes of clinically different mismatch-repair-deficient tumours with a differential immunogenic response potential
- Mar Giner-Calabuig
- , Seila De Leon
- & Rosa M. Xicola
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Article
| Open AccessPeritoneal metastases from colorectal cancer belong to Consensus Molecular Subtype 4 and are sensitised to oxaliplatin by inhibiting reducing capacity
- Jamila Laoukili
- , Alexander Constantinides
- & Onno Kranenburg
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Article
| Open AccessSpatial expression of IKK-alpha is associated with a differential mutational landscape and survival in primary colorectal cancer
- Meera Patel
- , Kathryn A. F. Pennel
- & Joanne Edwards
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Article
| Open AccessAdenoma characteristics associated with post-polypectomy proximal colon cancer incidence: a retrospective cohort study
- Rhea Harewood
- , Kate Wooldrage
- & Amanda J. Cross
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Inflammatory potential of diet and colorectal carcinogenesis: a prospective longitudinal cohort
- Zhuyue Li
- , Kang Wang
- & Xiaolian Jiang
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Early detection of colorectal neoplasia: application of a blood-based serological protein test on subjects undergoing population-based screening
- Jakob Kleif
- , Lars Nannestad Jørgensen
- & Hans Jørgen Nielsen
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Early life Lactobacillus rhamnosus GG colonisation inhibits intestinal tumour formation
- Xiang Liu
- , Ge Jin
- & Hailong Cao
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Risk-stratified selection to colonoscopy in FIT colorectal cancer screening: development and temporal validation of a prediction model
- Mette Kielsholm Thomsen
- , Lars Pedersen
- & Ellen M. Mikkelsen
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| Open AccessPrimary tumour immune response and lymph node yields in colon cancer
- Nikhil Lal
- , Dedrick Kok Hong Chan
- & Simon James Alexander Buczacki
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Article
| Open AccessOptimizing the colorectal cancer screening programme using faecal immunochemical test (FIT) in Flanders, Belgium from the “interval cancer” perspective
- Thuy Ngan Tran
- , Marc Peeters
- & Harlinde De Schutter
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The CBS-H2S axis promotes liver metastasis of colon cancer by upregulating VEGF through AP-1 activation
- Shihao Guo
- , Jichang Li
- & Shanwen Chen
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Effect of aflibercept plus FOLFIRI and potential efficacy biomarkers in patients with metastatic colorectal cancer: the POLAF trial
- Elena Élez
- , María Auxiliadora Gómez-España
- & Enrique Aranda
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| Open AccessOral antibiotic use and early-onset colorectal cancer: findings from a case-control study using a national clinical database
- Ronald McDowell
- , Sarah Perrott
- & Leslie Samuel
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Molecular pathways in post-colonoscopy versus detected colorectal cancers: results from a nested case–control study
- Roel M. M. Bogie
- , Chantal M. C. le Clercq
- & Beatriz Carvalho
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| Open AccessPhenome-wide association study (PheWAS) of colorectal cancer risk SNP effects on health outcomes in UK Biobank
- Xiaomeng Zhang
- , Xue Li
- & Evropi Theodoratou
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| Open AccessFaecal immunochemical test for patients with ‘high-risk’ bowel symptoms: a large prospective cohort study and updated literature review
- Helga E. Laszlo
- , Edward Seward
- & Michael Machesney
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SH2D4A downregulation due to loss of chromosome 8p is associated with poor prognosis and low T cell infiltration in colorectal cancer
- Takuro Matsumoto
- , Hirokazu Okayama
- & Koji Kono