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| Open AccessWhat can hospital emergency admissions prior to cancer diagnosis tell us about socio-economic inequalities in cancer diagnosis? Evidence from population-based data in England
- Aimilia Exarchakou
- , Bernard Rachet
- & Francisco Javier Rubio
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Article
| Open AccessFirst-line oxaliplatin-based chemotherapy and nivolumab for metastatic microsatellite-stable colorectal cancer—the randomised METIMMOX trial
- Anne Hansen Ree
- , Jūratė Šaltytė Benth
- & Sebastian Meltzer
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Correspondence |
Comment on: “Neoadjuvant chemotherapy is noninferior to chemoradiotherapy for early-onset locally advanced rectal cancer in the FOWARC trial”
- Letian Qiao
- , Yuan Liu
- & Qiumin Yang
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Article
| Open AccessGenetic risk impacts the association of menopausal hormone therapy with colorectal cancer risk
- Yu Tian
- , Yi Lin
- & Jenny Chang-Claude
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Article
| Open AccessIdentification of unique rectal cancer-specific subtypes
- Batuhan Kisakol
- , Anna Matveeva
- & Jochen H. M. Prehn
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Article
| Open AccessRoutes to diagnosis for hepatocellular carcinoma patients: predictors and associations with treatment and mortality
- Anya Burton
- , Jennifer Wilburn
- & Aileen Marshall
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Functional proteomics of colon cancer Consensus Molecular Subtypes
- Jaime Feliu
- , Angelo Gámez-Pozo
- & Lucía Trilla-Fuertes
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Article
| Open AccessCirculating 25-hydroxyvitamin D and survival outcomes of colorectal cancer: evidence from population-based prospective cohorts and Mendelian randomisation
- Xiaomeng Zhang
- , Yazhou He
- & Malcolm G. Dunlop
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Article
| Open AccessRNA expression of 6 genes from metastatic mucosal gastric cancer serves as the global prognostic marker for gastric cancer with functional validation
- Yun-Suhk Suh
- , Jieun Lee
- & Charles Lee
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Article
| Open AccessInhibition of the AURKA/YAP1 axis is a promising therapeutic option for overcoming cetuximab resistance in colorectal cancer stem cells
- Anxo Rio-Vilariño
- , Aiora Cenigaonandia-Campillo
- & Arancha Cebrián
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Article |
Early onset pancreatic cancer—exploring contemporary treatment and outcomes using real-world data
- Shehara Mendis
- , Lara Lipton
- & Belinda Lee
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Article
| Open AccessFluoropyrimidine type, patient age, tumour sidedness and mutation status as determinants of benefit in patients with metastatic colorectal cancer treated with EGFR monoclonal antibodies: individual patient data pooled analysis of randomised trials from the ARCAD database
- C. S. Karapetis
- , H. Liu
- & Q. Shi
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Article
| Open AccessSerum NY-ESO-1 antibody as a predictive biomarker for postoperative recurrence of gastric cancer: a multicenter prospective observational study
- Takuro Saito
- , Yukinori Kurokawa
- & Yuichiro Doki
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Article
| Open AccessInhibition of Aurora B kinase (AURKB) enhances the effectiveness of 5-fluorouracil chemotherapy against colorectal cancer cells
- Esha T. Shah
- , Christopher Molloy
- & Mark N. Adams
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Article
| Open AccessFarnesyl-transferase inhibitors show synergistic anticancer effects in combination with novel KRAS-G12C inhibitors
- Marcell Baranyi
- , Eszter Molnár
- & József Tímár
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Article
| Open AccessMetabolic heterogeneity affects trastuzumab response and survival in HER2-positive advanced gastric cancer
- Jun Wang
- , Na Sun
- & Axel Walch
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Article |
Predicting 5-year recurrence risk in colorectal cancer: development and validation of a histology-based deep learning approach
- Han Xiao
- , Zongpeng Weng
- & Sui Peng
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Article |
Dynamic nature of BRAF or KRAS p.G12C mutations in second-line therapy for advanced colorectal cancer patients: do early and late effects exist?
- Débora Contreras-Toledo
- , Paula Jiménez-Fonseca
- & Alberto Carmona-Bayonas
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Article |
Management of non-metastatic anal cancer in the elderly: ancillary study of the French multicenter prospective cohort FFCD-ANABASE
- Claire Gouriou
- , Claire Lemanski
- & Astrid Lièvre
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Article |
EGLN3 attenuates gastric cancer cell malignant characteristics by inhibiting JMJD8/NF-κB signalling activation independent of hydroxylase activity
- Fenglin Cai
- , Xiuding Yang
- & Jingyu Deng
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Article |
TRIM21/USP15 balances ACSL4 stability and the imatinib resistance of gastrointestinal stromal tumors
- Zhiwei Cui
- , Haoyu Sun
- & Hao Xu
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Article |
Prediction of response to neoadjuvant chemo-immunotherapy in patients with esophageal squamous cell carcinoma by a rapid breath test
- Qi Huang
- , Zheng Liu
- & Xiangnan Li
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Article
| Open AccessGenome-wide polygenic risk scores for colorectal cancer have implications for risk-based screening
- Max Tamlander
- , Bradley Jermy
- & Nina Mars
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Low blood level of tumour suppressor miR-5193 as a target of immunotherapy to PD-L1 in gastric cancer
- Hajime Kamiya
- , Shuhei Komatsu
- & Eigo Otsuji
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Article
| Open AccessNCI10066: a Phase 1/2 study of olaparib in combination with ramucirumab in previously treated metastatic gastric and gastroesophageal junction adenocarcinoma
- Michael Cecchini
- , James M. Cleary
- & Jill Lacy
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Tumour-associated macrophages and Schwann cells promote perineural invasion via paracrine loop in pancreatic ductal adenocarcinoma
- Bin Zhang
- , Xiaofeng Guo
- & Quanbo Zhou
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Article
| Open AccessCancer-related fatigue trajectories up to 5 years after curative treatment for oesophageal cancer
- Zhao Cheng
- , Asif Johar
- & Pernilla Lagergren
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Article
| Open AccessStroma AReactive Invasion Front Areas (SARIFA) improves prognostic risk stratification of perioperative chemotherapy treated oesophagogastric cancer patients from the MAGIC and the ST03 trial
- Bianca Grosser
- , Jake Emmerson
- & Heike I. Grabsch
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Association between weight cycling and risk of colorectal cancer: a prospective cohort study
- Suryun Kim
- , Dong Hoon Lee
- & NaNa Keum
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Primary resistance to immunotherapy in patients with a dMMR/MSI metastatic gastrointestinal cancer: who is at risk? An AGEO real-world study
- Clémence Flecchia
- , Edouard Auclin
- & Julien Taieb
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Stromal localization of inactive CD8+ T cells in metastatic mismatch repair deficient colorectal cancer
- Emre Küçükköse
- , Matthijs J. D. Baars
- & Yvonne Vercoulen
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Article
| Open AccessOpposing roles by KRAS and BRAF mutation on immune cell infiltration in colorectal cancer – possible implications for immunotherapy
- Sofia Edin
- , Björn Gylling
- & Richard Palmqvist
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Article
| Open AccessEfficacy and quality of life for FOLFOX/bevacizumab +/− irinotecan in first-line metastatic colorectal cancer—final results of the AIO CHARTA trial
- Hans-Joachim Schmoll
- , Julia Mann
- & Joseph Tintelnot
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Article |
Dexamethasone-sparing on days 2–4 with combined palonosetron, neurokinin-1 receptor antagonist, and olanzapine in cisplatin: a randomized phase III trial (SPARED Trial)
- Hiroko Minatogawa
- , Naoki Izawa
- & Takako Eguchi Nakajima
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APC/PIK3CA mutations and β-catenin status predict tankyrase inhibitor sensitivity of patient-derived colorectal cancer cells
- Mingjue Chen
- , Tetsuo Mashima
- & Hiroyuki Seimiya
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Article
| Open AccessEfficacy of GV1001 with gemcitabine/capecitabine in previously untreated patients with advanced pancreatic ductal adenocarcinoma having high serum eotaxin levels (KG4/2015): an open-label, randomised, Phase 3 trial
- Jung Hyun Jo
- , Yong-Tae Kim
- & Si Young Song
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Review Article
| Open AccessTotal neoadjuvant therapy in oesophageal and gastro-oesophageal junctional adenocarcinoma
- Hollie A. Clements
- , Tim J. Underwood
- & Russell D. Petty
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Preoperative chemoradiotherapy induces multiple pathways related to anti-tumour immunity in rectal cancer
- Ioannis M. Koukourakis
- , Erasmia Xanthopoulou
- & Anna Zygogianni
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Influence of cirrhosis on outcomes of patients with advanced intrahepatic cholangiocarcinoma receiving chemotherapy
- Constance d’Abrigeon
- , Mairéad G. McNamara
- & Julien Edeline
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Vitamin C intake and colorectal cancer survival according to KRAS and BRAF mutation: a prospective study in two US cohorts
- Shanshan Shi
- , Kai Wang
- & Mingyang Song
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Mismatch Repair system protein deficiency as a resistance factor for locally advanced rectal adenocarcinoma patients receiving neoadjuvant chemo-radiotherapy
- Andrea Pretta
- , Pina Ziranu
- & Mario Scartozzi
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Article
| Open AccessHistological diagnosis of polyploidy discriminates an aggressive subset of hepatocellular carcinomas with poor prognosis
- Takanori Matsuura
- , Yoshihide Ueda
- & Tomonori Matsumoto
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Article
| Open AccessLoss of NDUFS1 promotes gastric cancer progression by activating the mitochondrial ROS-HIF1α-FBLN5 signaling pathway
- Tao Chen
- , Dongbao Li
- & Jin Zhou
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Article
| Open AccessAnti-angiogenic therapy using the multi-tyrosine kinase inhibitor Regorafenib enhances tumor progression in a transgenic mouse model of ß-cell carcinogenesis
- Maren Juliane Egidi
- , Sebastian Krug
- & Heidi Griesmann
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Tertiary lymphoid structures correlate with enhancement of antitumor immunity in esophageal squamous cell carcinoma
- Shoichi Nakamura
- , Kenoki Ohuchida
- & Masafumi Nakamura
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Article |
Subclonal accumulation of immune escape mechanisms in microsatellite instability-high colorectal cancers
- Yuta Kobayashi
- , Atsushi Niida
- & Koshi Mimori
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Article
| Open AccessHistopathology and levels of proteins in plasma associate with survival after colorectal cancer diagnosis
- Magnus I. Magnusson
- , Bjarni A. Agnarsson
- & Kari Stefansson
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Combined blockade of mTOR and p21-activated kinases pathways prevents tumour growth in KRAS-mutated colorectal cancer
- Stefania Belli
- , Ada Pesapane
- & Roberto Bianco
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Review Article
| Open AccessAdvancing translational research for colorectal immuno-oncology
- Elaine M. Thomas
- , Josephine A. Wright
- & Susan L. Woods