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| Open AccessWhat can hospital emergency admissions prior to cancer diagnosis tell us about socio-economic inequalities in cancer diagnosis? Evidence from population-based data in England
- Aimilia Exarchakou
- , Bernard Rachet
- & Francisco Javier Rubio
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Functional proteomics of colon cancer Consensus Molecular Subtypes
- Jaime Feliu
- , Angelo Gámez-Pozo
- & Lucía Trilla-Fuertes
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Article
| Open AccessFluoropyrimidine type, patient age, tumour sidedness and mutation status as determinants of benefit in patients with metastatic colorectal cancer treated with EGFR monoclonal antibodies: individual patient data pooled analysis of randomised trials from the ARCAD database
- C. S. Karapetis
- , H. Liu
- & Q. Shi
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| Open AccessEfficacy and quality of life for FOLFOX/bevacizumab +/− irinotecan in first-line metastatic colorectal cancer—final results of the AIO CHARTA trial
- Hans-Joachim Schmoll
- , Julia Mann
- & Joseph Tintelnot
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Combined blockade of mTOR and p21-activated kinases pathways prevents tumour growth in KRAS-mutated colorectal cancer
- Stefania Belli
- , Ada Pesapane
- & Roberto Bianco
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Review Article
| Open AccessAdvancing translational research for colorectal immuno-oncology
- Elaine M. Thomas
- , Josephine A. Wright
- & Susan L. Woods
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| Open AccessProbing the diabetes and colorectal cancer relationship using gene – environment interaction analyses
- Niki Dimou
- , Andre E. Kim
- & Ulrike Peters
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| Open AccessPersonalised circulating tumour DNA assay with large-scale mutation coverage for sensitive minimal residual disease detection in colorectal cancer
- Seung-Bum Ryoo
- , Sunghoon Heo
- & Tae-You Kim
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Sleep and cancer recurrence and survival in patients with resected Stage III colon cancer: findings from CALGB/SWOG 80702 (Alliance)
- Seohyuk Lee
- , Chao Ma
- & Jeffrey A. Meyerhardt
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| Open AccessCancer-specific tissue-resident memory T-cells express ZNF683 in colorectal cancer
- Masatoshi Kitakaze
- , Mamoru Uemura
- & Hideshi Ishii
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A DNA methylation signature for the prediction of tumour recurrence in stage II colorectal cancer
- Min Li
- , Congcong Zhu
- & Qihong Huang
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An antibody–drug conjugate targeting GPR56 demonstrates efficacy in preclinical models of colorectal cancer
- Joan Jacob
- , Liezl E. Francisco
- & Kendra S. Carmon
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Review Article |
Ferroptosis in colorectal cancer: a future target?
- Hong Yan
- , Ronan Talty
- & Caroline H. Johnson
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Loss of alcohol dehydrogenase 1B in cancer-associated fibroblasts: contribution to the increase of tumor-promoting IL-6 in colon cancer
- Romain Villéger
- , Marina Chulkina
- & Irina V. Pinchuk
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Review Article |
A comprehensive systematic review of colorectal cancer screening clinical practices guidelines and consensus statements
- Marta Maes-Carballo
- , Manuel García-García
- & Aurora Bueno-Cavanillas
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Article
| Open AccessThe Glasgow Microenvironment Score and risk and site of recurrence in TNM I–III colorectal cancer
- P. G. Alexander
- , H. C. van Wyk
- & J. H. Park
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Review Article |
Lynch syndrome, molecular mechanisms and variant classification
- Amanda B. Abildgaard
- , Sofie V. Nielsen
- & Rasmus Hartmann-Petersen
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Investigation of the gut microbiome, bile acid composition and host immunoinflammatory response in a model of azoxymethane-induced colon cancer at discrete timepoints
- J. M. Keane
- , C. J. Walsh
- & N. P. Hyland
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Age alone is not a barrier to efficacy of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for colorectal peritoneal metastases: analysis of 1138 patients from the UK and Ireland Colorectal Peritoneal Metastases Registry
- Michael E. Kelly
- , Niall J. O’Sullivan
- & Jonathan Wild
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Long-term use of antihypertensive medications, hypertension and colorectal cancer risk and mortality: a prospective cohort study
- Yin Zhang
- , Mingyang Song
- & Edward L. Giovannucci
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Somatic hits in mismatch repair genes in colorectal cancer among non-seminoma testicular cancer survivors
- Berbel L. M. Ykema
- , Emilie C. H. Breekveldt
- & Monique E. van Leerdam
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Neuropeptide Y, a paracrine factor secreted by cancer cells, is an independent regulator of angiogenesis in colon cancer
- Debanjan Chakroborty
- , Sandeep Goswami
- & Chandrani Sarkar
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Correspondence |
Comment on “Development and validation of a novel strong prognostic index for colon cancer through a robust combination of laboratory features for systemic inflammation: a prognostic immune nutritional index”
- Hailun Xie
- , Yizhong Ge
- & Hanping Shi
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Correspondence |
Reply to comment(s) on “Development and validation of a novel strong prognostic index for colon cancer through a robust combination of laboratory features for systemic inflammation: a prognostic immune nutritional index”
- Sang-Hyuk Jung
- , Dokyoon Kim
- & Ji Won Park
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Article
| Open AccessEfficacy of FOLFIRI plus cetuximab vs FOLFIRI plus bevacizumab in 1st-line treatment of older patients with RAS wild-type metastatic colorectal cancer: an analysis of the randomised trial FIRE-3
- Laura E. Fischer
- , Sebastian Stintzing
- & Volker Heinemann
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Dynamic changes in longitudinal circulating tumour DNA profile during metastatic colorectal cancer treatment
- Sheehyun Kim
- , Yoojoo Lim
- & Tae-You Kim
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| Open AccessCalcium-binding protein S100P is a new target gene of MACC1, drives colorectal cancer metastasis and serves as a prognostic biomarker
- Felicitas Schmid
- , Mathias Dahlmann
- & Ulrike Stein
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Mutational signature profiling classifies subtypes of clinically different mismatch-repair-deficient tumours with a differential immunogenic response potential
- Mar Giner-Calabuig
- , Seila De Leon
- & Rosa M. Xicola
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Early life Lactobacillus rhamnosus GG colonisation inhibits intestinal tumour formation
- Xiang Liu
- , Ge Jin
- & Hailong Cao
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| Open AccessPrimary tumour immune response and lymph node yields in colon cancer
- Nikhil Lal
- , Dedrick Kok Hong Chan
- & Simon James Alexander Buczacki
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The CBS-H2S axis promotes liver metastasis of colon cancer by upregulating VEGF through AP-1 activation
- Shihao Guo
- , Jichang Li
- & Shanwen Chen
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| Open AccessOral antibiotic use and early-onset colorectal cancer: findings from a case-control study using a national clinical database
- Ronald McDowell
- , Sarah Perrott
- & Leslie Samuel
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Molecular pathways in post-colonoscopy versus detected colorectal cancers: results from a nested case–control study
- Roel M. M. Bogie
- , Chantal M. C. le Clercq
- & Beatriz Carvalho
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| Open AccessImpact of KRAS, BRAF and microsatellite instability status after cytoreductive surgery and HIPEC in a national cohort of colorectal peritoneal metastasis patients
- S. G. Larsen
- , M. A. Goscinski
- & H. Sorbye
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Variant allele frequency in baseline circulating tumour DNA to measure tumour burden and to stratify outcomes in patients with RAS wild-type metastatic colorectal cancer: a translational objective of the Valentino study
- Paolo Manca
- , Salvatore Corallo
- & Filippo Pietrantonio
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High PGD2 receptor 2 levels are associated with poor prognosis in colorectal cancer patients and induce VEGF expression in colon cancer cells and migration in a zebrafish xenograft model
- Pujarini Dash
- , Souvik Ghatak
- & Anita Sjölander
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| Open AccessDo presenting symptoms, use of pre-diagnostic endoscopy and risk of emergency cancer diagnosis vary by comorbidity burden and type in patients with colorectal cancer?
- Sara Benitez Majano
- , Georgios Lyratzopoulos
- & Cristina Renzi
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| Open AccessA stem cell marker KLF5 regulates CCAT1 via three-dimensional genome structure in colorectal cancer cells
- Takashi Takeda
- , Yuhki Yokoyama
- & Hirofumi Yamamoto
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CEA, CA19-9, circulating DNA and circulating tumour cell kinetics in patients treated for metastatic colorectal cancer (mCRC)
- David Sefrioui
- , Ludivine Beaussire
- & Frédéric Di Fiore
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Circulating tumour cells and cell-free DNA as a prognostic factor in metastatic colorectal cancer: the OMITERC prospective study
- Francesca Salvianti
- , Stefania Gelmini
- & Lorenzo Antonuzzo
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Aspirin reduces the incidence of metastasis in a pre-clinical study of Braf mutant serrated colorectal neoplasia
- Alexandra M. Kane
- , Cheng Liu
- & Vicki L. J. Whitehall
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The prognostic value of combined measures of the systemic inflammatory response in patients with colon cancer: an analysis of 1700 patients
- Allan M. Golder
- , Donald C. McMillan
- & Campbell S. Roxburgh
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| Open AccessFrequent post-operative monitoring of colorectal cancer using individualised ctDNA validated by multiregional molecular profiling
- Mizunori Yaegashi
- , Takeshi Iwaya
- & Satoshi S. Nishizuka
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| Open AccessPharmaceutical immunoglobulin G impairs anti-carcinoma activity of oxaliplatin in colon cancer cells
- Yuru Shang
- , Xianbin Zhang
- & Michael Linnebacher
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| Open AccessPrognostic value of desmoplastic reaction characterisation in stage II colon cancer: prospective validation in a Phase 3 study (SACURA Trial)
- Hideki Ueno
- , Megumi Ishiguro
- & Kenichi Sugihara
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| Open AccessCDX2 inhibits epithelial–mesenchymal transition in colorectal cancer by modulation of Snail expression and β-catenin stabilisation via transactivation of PTEN expression
- Junhui Yu
- , Shan Li
- & Xuejun Sun
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| Open AccessMutational profiles associated with resistance in patients with BRAFV600E mutant colorectal cancer treated with cetuximab and encorafenib +/− binimetinib or alpelisib
- Sanne C. F. A. Huijberts
- , Mirjam C. Boelens
- & Frans L. Opdam
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| Open AccessThe effect of vitamin D supplementation on survival in patients with colorectal cancer: systematic review and meta-analysis of randomised controlled trials
- Peter G. Vaughan-Shaw
- , Louis F. Buijs
- & Malcolm G. Dunlop