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| Open AccessCHARIOT: a phase I study of berzosertib with chemoradiotherapy in oesophageal and other solid cancers using time to event continual reassessment method
- S. R. Javed
- , S. Lord
- & M. A. Hawkins
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Article
| Open AccessStroma AReactive Invasion Front Areas (SARIFA) improves prognostic risk stratification of perioperative chemotherapy treated oesophagogastric cancer patients from the MAGIC and the ST03 trial
- Bianca Grosser
- , Jake Emmerson
- & Heike I. Grabsch
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Article
| Open AccessPAK inhibitor FRAX486 decreases the metastatic potential of triple-negative breast cancer cells by blocking autophagy
- Liang Lyu
- , Haiyan Li
- & Huihui Li
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MET exon 14 skipping mutation drives cancer progression and recurrence via activation of SMAD2 signalling
- Qiaoyan Liang
- , Yajun Hu
- & Bing Zhao
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Factors associated with the melanoma diagnostic interval in Ontario, Canada: a population-based study
- Meaghan E. Mavor
- , Timothy P. Hanna
- & Patti A. Groome
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Primary resistance to immunotherapy in patients with a dMMR/MSI metastatic gastrointestinal cancer: who is at risk? An AGEO real-world study
- Clémence Flecchia
- , Edouard Auclin
- & Julien Taieb
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Article
| Open AccessUrine-derived bladder cancer organoids (urinoids) as a tool for cancer longitudinal response monitoring and therapy adaptation
- Bastiaan J. Viergever
- , Daniëlle A. E. Raats
- & Richard P. Meijer
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Correspondence |
Tumour budding in head and neck cancer: what have we learnt and the next steps towards clinical implementation
- Alhadi Almangush
- , Antti A. Mäkitie
- & Ilmo Leivo
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Article
| Open AccessCompartment-specific multiomic profiling identifies SRC and GNAS as candidate drivers of epithelial-to-mesenchymal transition in ovarian carcinosarcoma
- C. Simon Herrington
- , Ailsa J. Oswald
- & Robert L. Hollis
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Periostin–TGF-β feedforward loop contributes to tumour-stroma crosstalk in liver metastatic outgrowth of colorectal cancer
- Bin Liu
- , Tiantian Wu
- & Gaoliang Ouyang
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Article
| Open AccessDiscordance between GCIG CA-125 progression and RECIST progression in the CALYPSO trial of patients with platinum-sensitive recurrent ovarian cancer
- Danka Sinikovic Zebic
- , Angelina Tjokrowidjaja
- & Chee Khoon Lee
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Article
| Open AccessCharacterisation of FLT3 alterations in childhood acute lymphoblastic leukaemia
- Angela Gutierrez-Camino
- , Chantal Richer
- & Daniel Sinnett
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Stromal localization of inactive CD8+ T cells in metastatic mismatch repair deficient colorectal cancer
- Emre Küçükköse
- , Matthijs J. D. Baars
- & Yvonne Vercoulen
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Article
| Open AccessOpposing roles by KRAS and BRAF mutation on immune cell infiltration in colorectal cancer – possible implications for immunotherapy
- Sofia Edin
- , Björn Gylling
- & Richard Palmqvist
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Low-dose metronomic cisplatin as an antiangiogenic and anti-inflammatory strategy for cancer
- Hiroshi Kikuchi
- , Nako Maishi
- & Kyoko Hida
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Article |
Downregulation of N4-acetylcytidine modification in myeloid cells attenuates immunotherapy and exacerbates hepatocellular carcinoma progression
- Nan Xu
- , Jianyong Zhuo
- & Qiang Wei
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Article |
Risk-reducing mastectomy and breast cancer mortality in women with a BRCA1 or BRCA2 pathogenic variant: an international analysis
- Kelly Metcalfe
- , Tomasz Huzarski
- & Stephanie Cohen
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Article
| Open AccessHealth benefits and harms of mammography screening in older women (75+ years)—a systematic review
- Erin Mathieu
- , Naomi Noguchi
- & Nehmat Houssami
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EEF1A2 promotes HIF1A mediated breast cancer angiogenesis in normoxia and participates in a positive feedback loop with HIF1A in hypoxia
- Saket Awadhesbhai Patel
- , Md. Khurshidul Hassan
- & Manjusha Dixit
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Correspondence |
Comment on “Development and validation of a multivariable model for prediction of malignant transformation and recurrence of oral epithelial dysplasia”
- Gargi Sarode
- & Sachin C. Sarode
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Article |
Dexamethasone-sparing on days 2–4 with combined palonosetron, neurokinin-1 receptor antagonist, and olanzapine in cisplatin: a randomized phase III trial (SPARED Trial)
- Hiroko Minatogawa
- , Naoki Izawa
- & Takako Eguchi Nakajima
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Article
| Open AccessCirculating tumour cells and PD-L1-positive small extracellular vesicles: the liquid biopsy combination for prognostic information in patients with metastatic non-small cell lung cancer
- Zahra Eslami-S
- , Luis Enrique Cortés-Hernández
- & Catherine Alix-Panabières
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APC/PIK3CA mutations and β-catenin status predict tankyrase inhibitor sensitivity of patient-derived colorectal cancer cells
- Mingjue Chen
- , Tetsuo Mashima
- & Hiroyuki Seimiya
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Enlarged tumour-draining lymph node with immune-activated profile predict favourable survival in non-metastatic colorectal cancer
- Xu Guan
- , Pu Cheng
- & Xishan Wang
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Article
| Open AccessIntegrating a microRNA signature as a liquid biopsy-based tool for the early diagnosis and prediction of potential therapeutic targets in pancreatic cancer
- Wenjie Shi
- , Thomas Wartmann
- & Ulf D. Kahlert
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Review Article |
Acquired copy number variation in prostate tumours: a review of common somatic copy number alterations, how they are formed and their clinical utility
- Dannielle E. O’Malley
- , Kelsie Raspin
- & Liesel M. FitzGerald
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Resistance to osimertinib in advanced EGFR-mutated NSCLC: a prospective study of molecular genotyping on tissue and liquid biopsies
- A. Leonetti
- , M. Verzè
- & M. Tiseo
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Article
| Open AccessTargeting the COMMD4–H2B protein complex in lung cancer
- Ming Tang
- , Joshua T. Burgess
- & Amila Suraweera
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Regorafenib in patients with advanced Ewing sarcoma: results of a non-comparative, randomised, double-blind, placebo-controlled, multicentre Phase II study
- Florence Duffaud
- , Jean-Yves Blay
- & Sylvie Chabaud
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Perspective
| Open AccessThe Cyclin-dependent kinase 1: more than a cell cycle regulator
- Giorgia Massacci
- , Livia Perfetto
- & Francesca Sacco
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Review Article
| Open AccessTotal neoadjuvant therapy in oesophageal and gastro-oesophageal junctional adenocarcinoma
- Hollie A. Clements
- , Tim J. Underwood
- & Russell D. Petty
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The novel CDK9 inhibitor, XPW1, alone and in combination with BRD4 inhibitor JQ1, for the treatment of clear cell renal cell carcinoma
- Zhijian Kuang
- , Kaiqiang Guo
- & Meijuan Fang
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Article
| Open AccessFascin-1 expression is associated with neuroendocrine prostate cancer and directly suppressed by androgen receptor
- Anthony Turpin
- , Carine Delliaux
- & Martine Duterque-Coquillaud
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Nimotuzumab plus concurrent chemo-radiotherapy in unresectable locally advanced oesophageal squamous cell carcinoma (ESCC): interim analysis from a Phase 3 clinical trial
- Xue Meng
- , Anping Zheng
- & Jinming Yu
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Article |
SIRT1 is an actionable target to restore p53 function in HPV-associated cancer therapy
- Irene Lo Cigno
- , Federica Calati
- & Marisa Gariglio
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Preoperative chemoradiotherapy induces multiple pathways related to anti-tumour immunity in rectal cancer
- Ioannis M. Koukourakis
- , Erasmia Xanthopoulou
- & Anna Zygogianni
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Frequency of peripheral PD-1+regulatory T cells is associated with treatment responses to PARP inhibitor maintenance in patients with epithelial ovarian cancer
- Junsik Park
- , Jung Chul Kim
- & Jung-Yun Lee
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Influence of cirrhosis on outcomes of patients with advanced intrahepatic cholangiocarcinoma receiving chemotherapy
- Constance d’Abrigeon
- , Mairéad G. McNamara
- & Julien Edeline
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Article
| Open AccessACAA2 is a novel molecular indicator for cancers with neuroendocrine phenotype
- Michelle Shen
- , Shiqin Liu
- & Tanya Stoyanova
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Review Article
| Open AccessThe role of TXNIP in cancer: a fine balance between redox, metabolic, and immunological tumor control
- Jinhai Deng
- , Teng Pan
- & Tony Ng
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Review Article
| Open AccessMolecular response assessment using circulating tumor DNA (ctDNA) in advanced solid tumors
- Jeffrey C. Thompson
- , Dylan G. Scholes
- & Charu Aggarwal
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Article
| Open AccessTargeting oncogenic microRNAs from the miR-371~373 and miR-302/367 clusters in malignant germ cell tumours causes growth inhibition through cell cycle disruption
- Shivani Bailey
- , Marta Ferraresso
- & Matthew J. Murray
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Article
| Open AccessEvaluation of tumour infiltrating lymphocytes in luminal breast cancer using artificial intelligence
- Shorouk Makhlouf
- , Noorul Wahab
- & Emad Rakha
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Article
| Open AccessDNA damage response inhibitors enhance tumour treating fields (TTFields) potency in glioma stem-like cells
- Aurelie Vanderlinden
- , Callum G. Jones
- & Spencer J. Collis
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Vitamin C intake and colorectal cancer survival according to KRAS and BRAF mutation: a prospective study in two US cohorts
- Shanshan Shi
- , Kai Wang
- & Mingyang Song
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Article
| Open AccessDevelopment and validation of a multivariable model for prediction of malignant transformation and recurrence of oral epithelial dysplasia
- Hanya Mahmood
- , Adam Shephard
- & Syed Ali Khurram
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Review Article |
Liquid biopsy: creating opportunities in brain space
- Rakesh Trivedi
- & Krishna P. Bhat
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Article |
Mismatch Repair system protein deficiency as a resistance factor for locally advanced rectal adenocarcinoma patients receiving neoadjuvant chemo-radiotherapy
- Andrea Pretta
- , Pina Ziranu
- & Mario Scartozzi
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Article
| Open AccessEvidence into practice: a national cohort study of NICE-recommended oncological drug therapy utilisation among women diagnosed with invasive breast cancer in England
- Melissa Ruth Gannon
- , David Dodwell
- & David Alan Cromwell
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