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Functional proteomics of colon cancer Consensus Molecular Subtypes
- Jaime Feliu
- , Angelo Gámez-Pozo
- & Lucía Trilla-Fuertes
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Article
| Open AccessPRRX1-TOP2A interaction is a malignancy-promoting factor in human malignant peripheral nerve sheath tumours
- Shota Takihira
- , Daisuke Yamada
- & Takeshi Takarada
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Article |
A cellular model provides insights into the pathogenicity of the oncogenic FOXL2 somatic variant p.Cys134Trp
- Laetitia Herman
- , Angélique Amo
- & Anne-Laure Todeschini
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Review Article |
Cyclin-dependent kinase 7 (CDK7) inhibitors as a novel therapeutic strategy for different molecular types of breast cancer
- Xue Song
- , Chen Fang
- & Rui Xu
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Article |
EGLN3 attenuates gastric cancer cell malignant characteristics by inhibiting JMJD8/NF-κB signalling activation independent of hydroxylase activity
- Fenglin Cai
- , Xiuding Yang
- & Jingyu Deng
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Article
| Open AccessCompartment-specific multiomic profiling identifies SRC and GNAS as candidate drivers of epithelial-to-mesenchymal transition in ovarian carcinosarcoma
- C. Simon Herrington
- , Ailsa J. Oswald
- & Robert L. Hollis
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Perspective
| Open AccessThe Cyclin-dependent kinase 1: more than a cell cycle regulator
- Giorgia Massacci
- , Livia Perfetto
- & Francesca Sacco
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Article
| Open AccessTargeting oncogenic microRNAs from the miR-371~373 and miR-302/367 clusters in malignant germ cell tumours causes growth inhibition through cell cycle disruption
- Shivani Bailey
- , Marta Ferraresso
- & Matthew J. Murray
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Article
| Open AccessDNA damage response inhibitors enhance tumour treating fields (TTFields) potency in glioma stem-like cells
- Aurelie Vanderlinden
- , Callum G. Jones
- & Spencer J. Collis
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Article
| Open AccessCharacterizing the mutational burden, DNA methylation landscape, and proteome of germ cell tumor-related somatic-type malignancies to identify the tissue-of-origin, mechanisms of therapy resistance, and druggable targets
- Felix Bremmer
- , Pailin Pongratanakul
- & Daniel Nettersheim
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Article |
PROTAC-mediated CDK degradation differentially impacts cancer cell cycles due to heterogeneity in kinase dependencies
- Vishnu Kumarasamy
- , Zhe Gao
- & Erik S. Knudsen
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Article
| Open AccessSynthetic viability induces resistance to immune checkpoint inhibitors in cancer cells
- Mingyue Liu
- , Qi Dong
- & Yunyan Gu
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Article
| Open AccessThe emergence of RAS mutations in patients with RAS wild-type mCRC receiving cetuximab as first-line treatment: a noninterventional, uncontrolled multicenter study
- Hsiang-Lin Tsai
- , Chun-Chi Lin
- & Jaw-Yuan Wang
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Article
| Open AccessMiR-662 is associated with metastatic relapse in early-stage breast cancer and promotes metastasis by stimulating cancer cell stemness
- Margherita Puppo
- , Manoj Kumar Valluru
- & Philippe Clézardin
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Article |
HDAC5 modulates SATB1 transcriptional activity to promote lung adenocarcinoma
- Shalakha Sharma
- , Witty Tyagi
- & Sanjeev Das
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Article
| Open AccessArginine regulates HSPA5/BiP translation through ribosome pausing in triple-negative breast cancer cells
- Christina M. Vidal
- , Ching Ouyang
- & David K. Ann
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Article |
Insulin receptor expression to predict resistance to axitinib and elucidation of the underlying molecular mechanism in metastatic renal cell carcinoma
- Masayuki Takahashi
- , Kei Daizumoto
- & Hiroomi Kanayama
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Article |
NDRG1 facilitates self-renewal of liver cancer stem cells by preventing EpCAM ubiquitination
- Qian Cheng
- , Shanglei Ning
- & Jiye Zhu
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Article
| Open AccessThe CDK7 inhibitor CT7001 (Samuraciclib) targets proliferation pathways to inhibit advanced prostate cancer
- Theodora A. Constantin
- , Anabel Varela-Carver
- & Charlotte L. Bevan
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Review Article |
The critical roles of m6A RNA methylation in lung cancer: from mechanism to prognosis and therapy
- Mei-Ning Diao
- , Xiao-Jing Zhang
- & Yin-Feng Zhang
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Article
| Open AccessTumour-educated platelets for breast cancer detection: biological and technical insights
- Marte C. Liefaard
- , Kat S. Moore
- & Esther H. Lips
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Review Article
| Open AccessAn old friend with a new face: tRNA-derived small RNAs with big regulatory potential in cancer biology
- Arianna Di Fazio
- & Monika Gullerova
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Article |
Transcriptome analysis of newly established carboplatin-resistant ovarian cancer cell model reveals genes shared by drug resistance and drug-induced EMT
- Juran Kralj
- , Margareta Pernar Kovač
- & Anamaria Brozovic
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Article |
STAT3 potentiates RNA polymerase I-directed transcription and tumor growth by activating RPA34 expression
- Cheng Zhang
- , Juan Wang
- & Wensheng Deng
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Article
| Open AccessMismatch repair markers in preoperative and operative endometrial cancer samples; expression concordance and prognostic value
- Hege F. Berg
- , Hilde Engerud
- & Camilla Krakstad
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Article
| Open AccessComprehensive small RNA-sequencing of primary myeloma cells identifies miR-105-5p as a predictor of patient survival
- Kristin Roseth Aass
- , Tonje Marie Vikene Nedal
- & Robin Mjelle
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Review Article |
Lynch syndrome, molecular mechanisms and variant classification
- Amanda B. Abildgaard
- , Sofie V. Nielsen
- & Rasmus Hartmann-Petersen
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Article |
Somatic mutations in DCC are associated with genomic instability and favourable outcomes in melanoma patients treated with immune checkpoint inhibitors
- Yuting Li
- , Qinghua Wang
- & Lujun Zhao
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Article |
Clinical characteristics and molecular aspects of low-grade serous ovarian and peritoneal cancer: a multicenter, observational, retrospective analysis of MITO Group (MITO 22)
- Lucia Musacchio
- , Daniela Califano
- & Sandro Pignata
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Article
| Open AccessTopoisomerase I poison-triggered immune gene activation is markedly reduced in human small-cell lung cancers by impairment of the cGAS/STING pathway
- Jessica Marinello
- , Andrea Arleo
- & Giovanni Capranico
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Article |
EphA2 on urinary extracellular vesicles as a novel biomarker for bladder cancer diagnosis and its effect on the invasiveness of bladder cancer
- Eisuke Tomiyama
- , Kazutoshi Fujita
- & Norio Nonomura
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Article
| Open AccessAberrant promoter methylation contributes to LRIG1 silencing in basal/triple-negative breast cancer
- Maxine Umeh-Garcia
- , Henriette O’Geen
- & Colleen A. Sweeney
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Article |
Methylation-mediated silencing of protein kinase C zeta induces apoptosis avoidance through ATM/CHK2 inactivation in dedifferentiated chondrosarcoma
- Eijiro Shimada
- , Yoshihiro Matsumoto
- & Yasuharu Nakashima
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Editorial |
Standardisation of protocols can be crucial in long non-coding RNA research
- Kinga Németh
- & George A. Calin
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Article |
PCK1 regulates neuroendocrine differentiation in a positive feedback loop of LIF/ZBTB46 signalling in castration-resistant prostate cancer
- Yu-Ching Wen
- , Chien-Liang Liu
- & Yen-Nien Liu
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Review Article
| Open AccessLong non-coding RNAs are involved in alternative splicing and promote cancer progression
- Jiawei Ouyang
- , Yu Zhong
- & Wei Xiong
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Article
| Open AccessRisk-stratification of HPV-positive women with low-grade cytology by FAM19A4/miR124-2 methylation and HPV genotyping
- Stèfanie Dick
- , Frederique J. Vink
- & Johannes Berkhof
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Article |
miRNA-seq and clinical evaluation in multiple myeloma: miR-181a overexpression predicts short-term disease progression and poor post-treatment outcome
- Maria-Alexandra Papadimitriou
- , Aristea-Maria Papanota
- & Andreas Scorilas
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Article |
Novel evidence for m6A methylation regulators as prognostic biomarkers and FTO as a potential therapeutic target in gastric cancer
- Tadanobu Shimura
- , Raju Kandimalla
- & Ajay Goel
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Review Article |
Expression and functions of long non-coding RNA NEAT1 and isoforms in breast cancer
- Erik Knutsen
- , Adrian L. Harris
- & Maria Perander
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Article |
Mapping of truncated O-glycans in cancers of epithelial and non-epithelial origin
- Troels Boldt Rømer
- , Mikkel Koed Møller Aasted
- & Hans Heugh Wandall
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Article |
Peroxiredoxin-1 Tyr194 phosphorylation regulates LOX-dependent extracellular matrix remodelling in breast cancer
- Shireen Attaran
- , John J. Skoko
- & Carola A. Neumann
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Article |
SLC38A4 functions as a tumour suppressor in hepatocellular carcinoma through modulating Wnt/β-catenin/MYC/HMGCS2 axis
- Jie Li
- , Ming-han Li
- & Ji-hang Yuan
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Article |
Tandem histone methyltransferase upregulation defines a unique aggressive prostate cancer phenotype
- Mikolaj Filon
- , Joseph Gawdzik
- & David Jarrard
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Comment |
Myeloma-bone marrow adipocyte axis in tumour survival and treatment response
- Abbas Jafari
- , Heather Fairfield
- & Michaela R. Reagan
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Article |
Schlafen 11 predicts response to platinum-based chemotherapy in gastric cancers
- Tsuyoshi Takashima
- , Daiki Taniyama
- & Wataru Yasui
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Article |
Autophagy mediated lipid catabolism facilitates glioma progression to overcome bioenergetic crisis
- Chenran Wang
- , Michael A. Haas
- & Jun-Lin Guan
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Article
| Open AccessCREPT/RPRD1B promotes tumorigenesis through STAT3-driven gene transcription in a p300-dependent manner
- Wanli Zhai
- , Xiongjun Ye
- & Zhijie Chang
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Editorial
| Open AccessThe role of Schlafen 11 (SLFN11) as a predictive biomarker for targeting the DNA damage response
- Niamh Coleman
- , Bingnan Zhang
- & Timothy A. Yap
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- Cell division
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- Post-translational modifications
- Protein folding
- Proteolysis
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- Riboswitches
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- Single-molecule biophysics
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