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| Open AccessBlockade of TGF-β and PD-L1 by bintrafusp alfa promotes survival in preclinical ovarian cancer models by promoting T effector and NK cell responses
- Jacob Kment
- , Daniel Newsted
- & Andrew W. Craig
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Review Article
| Open AccessPredictable changes in the accuracy of human papillomavirus tests after vaccination: review with implications for performance monitoring in cervical screening
- Matejka Rebolj
- , Adam R. Brentnall
- & Kate Cuschieri
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Article |
Single-cell sequencing reveals VEGFR as a potential target for CAR-T cell therapy in chordoma
- Huantong Wu
- , Xinqiang Li
- & Zan Chen
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Article |
SPP1 represents a therapeutic target that promotes the progression of oesophageal squamous cell carcinoma by driving M2 macrophage infiltration
- Chen Wang
- , Yutong Li
- & Renle Du
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Article
| Open AccessPathway-based signatures predict patient outcome, chemotherapy benefit and synthetic lethal dependencies in invasive lobular breast cancer
- John Alexander
- , Koen Schipper
- & Syed Haider
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Article
| Open AccessNeratinib could be effective as monotherapy or in combination with trastuzumab in HER2-low breast cancer cells and organoid models
- Maryam Arshad
- , Abul Azad
- & Anthony Kong
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Article
| Open AccessDynamic genomic changes in methotrexate-resistant human cancer cell lines beyond DHFR amplification suggest potential new targets for preventing drug resistance
- Xiang-Ning Meng
- , Jin-Fa Ma
- & Song-Bin Fu
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Article
| Open AccessCancer-associated fibroblasts expressing fibroblast activation protein and podoplanin in non-small cell lung cancer predict poor clinical outcome
- Layla Mathieson
- , Lilian Koppensteiner
- & Ahsan R. Akram
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DRP1 inhibition-mediated mitochondrial elongation abolishes cancer stemness, enhances glutaminolysis, and drives ferroptosis in oral squamous cell carcinoma
- Zhen Wang
- , Shouyi Tang
- & Qianming Chen
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Article
| Open AccessGCN5 mediates DNA-PKcs crotonylation for DNA double-strand break repair and determining cancer radiosensitivity
- Yang Han
- , Hongling Zhao
- & Ping-Kun Zhou
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Article
| Open AccessGenetic risk impacts the association of menopausal hormone therapy with colorectal cancer risk
- Yu Tian
- , Yi Lin
- & Jenny Chang-Claude
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Article
| Open AccessFibroblast activation protein-targeted near-infrared photoimmunotherapy depletes immunosuppressive cancer-associated fibroblasts and remodels local tumor immunity
- Masaaki Akai
- , Kazuhiro Noma
- & Toshiyoshi Fujiwara
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Article
| Open AccessMethylation analysis of DCC gene in saliva samples is an efficient method for non-invasive detection of superficial hypopharyngeal cancer
- Ryosuke Hirai
- , Hideaki Kinugasa
- & Motoyuki Otsuka
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Article
| Open AccessIdentification of unique rectal cancer-specific subtypes
- Batuhan Kisakol
- , Anna Matveeva
- & Jochen H. M. Prehn
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Review Article |
Incidental pathogenic germline alterations detected through liquid biopsy in patients with solid tumors: prevalence, clinical utility and implications
- Juan Carlos Laguna
- , Belén Pastor
- & Laura Mezquita
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Article |
Extending the dosing intervals of nivolumab: model-based simulations in unselected cancer patients
- Alicja Puszkiel
- , Guillaume Bianconi
- & Benoit Blanchet
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Article
| Open AccessPersistence of peripheral CD8 + CD28− T cells indicates a favourable outcome and tumour immunity in first-line HER2-positive metastatic breast cancer
- Xiaoran Liu
- , Xiangming Cheng
- & Huiping Li
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Article
| Open AccessCombination of EZH2 and ATM inhibition in BAP1-deficient mesothelioma
- Nick Landman
- , Danielle Hulsman
- & Maarten van Lohuizen
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Article |
Functional proteomics of colon cancer Consensus Molecular Subtypes
- Jaime Feliu
- , Angelo Gámez-Pozo
- & Lucía Trilla-Fuertes
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Article
| Open AccessSingle-cell RNA sequencing analysis of vestibular schwannoma reveals functionally distinct macrophage subsets
- Paramita Baruah
- , Christopher Mahony
- & Adam P. Croft
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Article
| Open AccessRNA expression of 6 genes from metastatic mucosal gastric cancer serves as the global prognostic marker for gastric cancer with functional validation
- Yun-Suhk Suh
- , Jieun Lee
- & Charles Lee
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Article
| Open AccessInhibition of the AURKA/YAP1 axis is a promising therapeutic option for overcoming cetuximab resistance in colorectal cancer stem cells
- Anxo Rio-Vilariño
- , Aiora Cenigaonandia-Campillo
- & Arancha Cebrián
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Article |
Long-term trends in incidence, characteristics and prognosis of screen-detected and interval cancers in women participating in the Dutch breast cancer screening programme
- Daniëlle E. ten Velde
- , Lucien E. M. Duijm
- & Adri C. Voogd
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Article |
Platelets induce CD39 expression in tumor cells to facilitate tumor metastasis
- Zhaochen Ning
- , Keyan Liu
- & Huabao Xiong
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Article
| Open AccessAnti-integrin αvβ6 autoantibodies are a potential biomarker for ulcerative colitis-like immune checkpoint inhibitor-induced colitis
- Masataka Yokode
- , Masahiro Shiokawa
- & Hiroshi Seno
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Article
| Open AccessCannabinoids induce cell death in leukaemic cells through Parthanatos and PARP-related metabolic disruptions
- M. Medrano
- , M. Contreras
- & J. A. Pérez-Simón
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Article |
EIF4A3-negatively driven circular RNA β-catenin (circβ-catenin) promotes colorectal cancer progression via miR-197-3p/CTNND1 regulatory axis
- Li-Qiang Deng
- , Chuan-Jian Shi
- & Jin-Fang Zhang
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Article |
A metabolic map and artificial intelligence-aided identification of nasopharyngeal carcinoma via a single-cell Raman platform
- Jiabao Xu
- , Dayang Chen
- & Dan Xiong
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Article |
Pirfenidone alleviates fibrosis by acting on tumour–stroma interplay in pancreatic cancer
- Yalan Lei
- , Jin Xu
- & Si Shi
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Article
| Open AccessPRRX1-TOP2A interaction is a malignancy-promoting factor in human malignant peripheral nerve sheath tumours
- Shota Takihira
- , Daisuke Yamada
- & Takeshi Takarada
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Article
| Open AccessTargeting Galectin 3 illuminates its contributions to the pathology of uterine serous carcinoma
- Yusuke Matoba
- , Dominique T. Zarrella
- & Bo R. Rueda
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Article |
A cellular model provides insights into the pathogenicity of the oncogenic FOXL2 somatic variant p.Cys134Trp
- Laetitia Herman
- , Angélique Amo
- & Anne-Laure Todeschini
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Article
| Open AccessSingle-cell RNA sequencing reveals myeloid and T cell co-stimulation mediated by IL-7 anti-cancer immunotherapy
- Hye Hyeon Eum
- , Dasom Jeong
- & Hae-Ock Lee
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Review Article
| Open AccessRanolazine: a potential anti-metastatic drug targeting voltage-gated sodium channels
- Mustafa B. A. Djamgoz
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Article
| Open AccessRisk of cancer and serious disease in Danish patients with urgent referral for serious non-specific symptoms and signs of cancer in Funen 2014–2021
- Rasmus Birkholm Grønnemose
- , Per Syrak Hansen
- & Peter Thye-Rønn
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Article
| Open AccessFluoropyrimidine type, patient age, tumour sidedness and mutation status as determinants of benefit in patients with metastatic colorectal cancer treated with EGFR monoclonal antibodies: individual patient data pooled analysis of randomised trials from the ARCAD database
- C. S. Karapetis
- , H. Liu
- & Q. Shi
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Article
| Open AccessCapivasertib combines with docetaxel to enhance anti-tumour activity through inhibition of AKT-mediated survival mechanisms in prostate cancer
- Cath Eberlein
- , Stuart C. Williamson
- & Simon T. Barry
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Article
| Open AccessTumor Treating Fields (TTFields) combined with the drug repurposing approach CUSP9v3 induce metabolic reprogramming and synergistic anti-glioblastoma activity in vitro
- Qiyu Cao
- , Annika Hajosch
- & Georg Karpel-Massler
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Article
| Open AccessAge at lung cancer diagnosis in females versus males who never smoke by race and ethnicity
- Batel Blechter
- , Jason Y. Y. Wong
- & Qing Lan
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Article
| Open AccessCAnceR IN PreGnancy (CARING) – a retrospective study of cancer diagnosed during pregnancy in the United Kingdom
- M. A. Baxter
- , M. Denholm
- & J. Harris
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Correspondence |
Comment on “Pathological complete response, category change, and prognostic significance of HER2-low breast cancer receiving neoadjuvant treatment: a multicenter analysis of 2489 cases”
- Tianfei Yu
- , Changfei Yang
- & Ming Li
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Review Article |
Cyclin-dependent kinase 7 (CDK7) inhibitors as a novel therapeutic strategy for different molecular types of breast cancer
- Xue Song
- , Chen Fang
- & Rui Xu
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Article |
ABCC4 suppresses glioblastoma progression and recurrence by restraining cGMP-PKG signalling
- Jung-Ying Chiang
- , Sung-Tai Wei
- & Chia-Hung Hsieh
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Article |
IL-24 improves efficacy of CAR-T cell therapy by targeting stemness of tumor cells
- Kai Zhang
- , Wenhao Hu
- & Yi Zhang
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Article |
Germline predictors for bevacizumab induced hypertensive crisis in ECOG-ACRIN 5103 and BEATRICE
- Fei Shen
- , Guanglong Jiang
- & Bryan P. Schneider
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Article
| Open AccessUnraveling the impact of cancer-associated fibroblasts on hypovascular pancreatic neuroendocrine tumors
- Ting-Yu Lai
- , Tsai-Chen Chiang
- & Wen-Hwa Lee
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Article
| Open AccessAHRR and SFRP2 in primary versus recurrent high-grade serous ovarian carcinoma and their prognostic implication
- Nanna Monjé
- , Mihnea P. Dragomir
- & Eliane T. Taube
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Article
| Open AccessSynergistic induction of tertiary lymphoid structures by chemoimmunotherapy in bladder cancer
- Lu Zhang
- , Ruiyun Zhang
- & Jinhai Fan
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Article
| Open AccessSerum NY-ESO-1 antibody as a predictive biomarker for postoperative recurrence of gastric cancer: a multicenter prospective observational study
- Takuro Saito
- , Yukinori Kurokawa
- & Yuichiro Doki
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