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Enhancing CAR-T cells: unleashing lasting impact potential with phytohemagglutinin activation in in vivo leukemia model
- Berranur Sert
- , Gamze Gulden
- & Cihan Tastan
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Article
| Open Access
Siglec-15 on macrophages suppress the immune microenvironment in patients with PD-L1 negative non-metastasis lung adenocarcinoma
- Ziqi Huang
- , Yan Guo
- & Lili Yang
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Article
| Open Access
Antibody-mediated delivery of viral epitopes to redirect EBV-specific CD8+ T-cell immunity towards cancer cells
- Willemijn van der Wulp
- , Dennis F. G. Remst
- & Mirjam H. M. Heemskerk
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Review Article
| Open Access
Therapeutic utility of engineered myeloid cells in the tumor microenvironment
- Alessandro Canella
- & Prajwal Rajappa
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Article |
Rational pemetrexed combined with CIK therapy plus anti-PD-1 mAbs administration sequence will effectively promote the efficacy of CIK therapy in non-small cell lung cancer
- Shaochuan Liu
- , Yuan Meng
- & Qian Sun
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High CAR intensity of expression confers enhanced antitumor effect against lymphoma without functional exhaustion
- Ana Carolina Caballero
- , Laura Escribà-Garcia
- & Javier Briones
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Article
| Open Access
Regional infusion of a class C TLR9 agonist enhances liver tumor microenvironment reprogramming and MDSC reduction to improve responsiveness to systemic checkpoint inhibition
- Chandra C. Ghosh
- , Kara R. Heatherton
- & Steven C. Katz
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Article |
Activation of CEACAM1 with an agonistic monoclonal antibody results in inhibition of melanoma cells
- Ilan Zaffran
- , Nadine Landolina
- & Francesca Levi-Schaffer
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Article
| Open Access
Description and optimization of a multiplex bead-based flow cytometry method (MBFCM) to characterize extracellular vesicles in serum samples from patients with hematological malignancies
- Lin Li
- , André Görgens
- & Helga Schmetzer
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Article |
Homeostatic cytokines tune naivety and stemness of cord blood-derived transgenic T cells
- Chrystel Marton
- , Patricia Mercier-Letondal
- & Yann Godet
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Article |
CXCR4 and anti-BCMA CAR co-modified natural killer cells suppress multiple myeloma progression in a xenograft mouse model
- Yu Yang Ng
- , Zhicheng Du
- & Shu Wang
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Article |
Enhanced antitumor immune response in melanoma tumor model by anti-PD-1 small interference RNA encapsulated in nanoliposomes
- Mehdi Barati
- , Farshad Mirzavi
- & Mahmoud Reza Jaafari
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Correspondence |
Protean role of epigenetic mechanisms and their impact in regulating the Tregs in TME
- A. S. Smiline Girija
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Review Article |
Combination therapy with CAR T cells and oncolytic viruses: a new era in cancer immunotherapy
- Ramazan Rezaei
- , Hadi Esmaeili Gouvarchin Ghaleh
- & Akbar Ghorbani Alvanegh
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Article |
CF33-hNIS-antiPDL1 virus primes pancreatic ductal adenocarcinoma for enhanced anti-PD-L1 therapy
- Zhifang Zhang
- , Annie Yang
- & Yanghee Woo
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Review Article |
Cancer immunotherapies revisited: state of the art of conventional treatments and next-generation nanomedicines
Schematic summary of the main currently existing immunotherapies; from therapeutic antibodies to newly developed nanomedicines.
- Coral García-Fernández
- , Anna Saz
- & Salvador Borrós
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Review Article |
Nanomedicine-based cancer immunotherapy: recent trends and future perspectives
- Vinoth-Kumar Lakshmanan
- , Shlok Jindal
- & Salem Chouaib
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Review Article |
Recent updates on chimeric antigen receptor T cell therapy for hepatocellular carcinoma
- Jiaojiao Guo
- & Qi Tang
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Article
| Open Access
Therapeutic anti-glioma effect of the combined action of PCSK inhibitor with the anti-tumoral factors secreted by Poly (I:C)-stimulated macrophages
- Mélanie Rose
- , Marie Duhamel
- & Michel Salzet
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Review Article
| Open Access
Viroimmunotherapy for breast cancer: promises, problems and future directions
- Shyambabu Chaurasiya
- & Yuman Fong
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Article
| Open Access
Chimeric Antigen Receptor-modified T cells targeting EphA2 for the immunotherapy of paediatric bone tumours
- Kenneth Hsu
- , Shiloh Middlemiss
- & Belinda Kramer
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Article
| Open Access
Immunostimulatory oncolytic virotherapy for multiple myeloma targeting 4-1BB and/or CD40
- Jessica Wenthe
- , Sedigheh Naseri
- & Angelica Loskog
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Article |
Cancer immunotherapy using the Fusion gene of Sendai virus
- Jiayu A. Tai
- , Chin Yang Chang
- & Yasufumi Kaneda
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Article |
Autologous CD19-directed chimeric antigen receptor-T cell is an effective and safe treatment to refractory or relapsed diffuse large B-cell lymphoma
- Fang Bao
- , Wei Wan
- & Hongmei Jing
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Article |
Intratumoral expression using a NFkB-based promoter enhances IL12 antitumor efficacy
- Guillermo Garaulet
- , Gema Pérez-Chacon
- & Antonio Rodríguez
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Article |
Intratumoral IFN-α gene delivery reduces tumor-infiltrating regulatory T cells through the downregulation of tumor CCL17 expression
- Aya Hirata
- , Hisayoshi Hashimoto
- & Kazunori Aoki
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Article
| Open Access
T-bet promotes potent antitumor activity of CD4+ CAR T cells
- Albert T Gacerez
- & Charles L Sentman
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Original Article
| Open Access
Phase I/II clinical trial to assess safety and efficacy of intratumoral and subcutaneous injection of HVJ-E in castration-resistant prostate cancer patients
- K Fujita
- , Y Nakai
- & N Nonomura
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Review |
Immunosuppression in liver tumors: opening the portal to effective immunotherapy
- P Guha
- , J Reha
- & S C Katz
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Review |
Intraperitoneal immunotherapy: historical perspectives and modern therapy
- W F Morano
- , A Aggarwal
- & W B Bowne
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Review |
Chimeric antigen receptors for treatment of glioblastoma: a practical review of challenges and ways to overcome them
- S Sengupta
- , G Mao
- & P Sampath
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Original Article |
Regional CAR-T cell infusions for peritoneal carcinomatosis are superior to systemic delivery
- S C Katz
- , G R Point
- & R P Junghans
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Original Article |
Efficient expression of bioactive murine IL12 as a self-processing P2A polypeptide driven by inflammation-regulated promoters in tumor cell lines
- C Lorenzo
- , G Pérez-Chacón
- & A Rodríguez
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Original Article |
Modulating mammary tumor growth, metastasis and immunosuppression by siRNA-induced MIF reduction in tumor microenvironment
- M Zhang
- , L Yan
- & J A Kim
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Original Article |
IL-12 conditioning improves retrovirally mediated transduction efficiency of CD8+ T cells
- K Andrijauskaite
- , S Suriano
- & M P Rubinstein
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Original Article |
Extranodal induction of therapeutic immunity in the tumor microenvironment after intratumoral delivery of Tbet gene-modified dendritic cells
- L Chen
- , J L Taylor
- & W J Storkus
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Original Article |
CCL19 as an adjuvant for intradermal gene gun immunization in a Her2/neu mouse tumor model: improved vaccine efficacy and a role for B cells as APC
- T Nguyen-Hoai
- , O Hohn
- & J Westermann
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Original Article |
Multivalent immunity targeting tumor-associated antigens by intra-lymph node DNA-prime, peptide-boost vaccination
- K A Smith
- , Z Qiu
- & A Bot
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Original Article |
Direct and indirect antitumor effects by human peripheral blood lymphocytes expressing both chimeric immune receptor and interleukin-2 in ovarian cancer xenograft model
- J M Lee
- , S H Yoon
- & T-G Kim
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Original Article
| Open Access
Antigen quality determines the efficiency of antitumor immune responses generated in the absence of regulatory T cells
- A-S Bergot
- , A Durgeau
- & D Klatzmann
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Original Article |
Effective immunotherapy of weakly immunogenic solid tumours using a combined immunogene therapy and regulatory T-cell inactivation
- M C Whelan
- , G Casey
- & G C O'Sullivan
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Original Article |
Potent antitumor effects of combined therapy with a telomerase-specific, replication-competent adenovirus (OBP-301) and IL-2 in a mouse model of renal cell carcinoma
- P Huang
- , H Kaku
- & H Kumon
Tumor stroma-derived ANGPTL2 potentiates immune checkpoint inhibitor efficacy
T-cell programming in pancreatic adenocarcinoma: a review
Eliciting protective immune responses against murine myeloma challenge in lymphopenia mice through adoptive transfer of tumor antigen-specific lymphocytes and immunization of tumor vaccine secreting mIL-21