Featured
-
-
Article |
Mitochondrial DNA copy number plays opposing roles in T-lymphocyte infiltration of colorectal cancer based on mismatch repair status: new directions for immunotherapy?
- Mian Chen
- , Huashan Liu
- & Liang Huang
-
Article
| Open AccessPeroxisomal β-oxidation enzyme, DECR2, regulates lipid metabolism and promotes treatment resistance in advanced prostate cancer
- Chui Yan Mah
- , An Dieu Trang Nguyen
- & Lisa M. Butler
-
Article
| Open AccessIntegrative score based on CDK6, PD-L1 and TMB predicts response to platinum-based chemotherapy and PD-1/PD-L1 blockade in muscle-invasive bladder cancer
- Xiaohe Su
- , Kaifeng Jin
- & Jiejie Xu
-
Article
| Open AccessGlioblastoma biomarkers in urinary extracellular vesicles reveal the potential for a ‘liquid gold’ biopsy
- Susannah M. Hallal
- , Ágota Tűzesi
- & Kimberley L. Alexander
-
Article |
Minimum latency effects for cancer associated with exposures to radiation or other carcinogens
- Mark P. Little
- , Markus Eidemüller
- & A. Iulian Apostoaei
-
Article
| Open AccessPhase 1 study of high-dose DFMO, celecoxib, cyclophosphamide and topotecan for patients with relapsed neuroblastoma: a New Approaches to Neuroblastoma Therapy trial
- Michael D. Hogarty
- , David S. Ziegler
- & Araz Marachelian
-
Article
| Open AccessMed23 deficiency reprograms the tumor microenvironment to promote lung tumorigenesis
- Xiaobo Fu
- , Siming Liu
- & Gang Wang
-
Article |
Dynamic nature of BRAF or KRAS p.G12C mutations in second-line therapy for advanced colorectal cancer patients: do early and late effects exist?
- Débora Contreras-Toledo
- , Paula Jiménez-Fonseca
- & Alberto Carmona-Bayonas
-
Article |
EGLN3 attenuates gastric cancer cell malignant characteristics by inhibiting JMJD8/NF-κB signalling activation independent of hydroxylase activity
- Fenglin Cai
- , Xiuding Yang
- & Jingyu Deng
-
Article |
The clinical implication and translational research of OSCC differentiation
- Qianhui Shang
- , Yuchen Jiang
- & Hao Xu
-
Article |
TRIM21/USP15 balances ACSL4 stability and the imatinib resistance of gastrointestinal stromal tumors
- Zhiwei Cui
- , Haoyu Sun
- & Hao Xu
-
Article |
p4EBP1 staining predicts outcome in ER-positive endocrine-resistant metastatic breast cancer patients treated with everolimus and exemestane
- Hélène Vanacker
- , Isabelle Treilleux
- & Thomas Bachelot
-
Article
| Open AccessResistance to BRAF inhibition explored through single circulating tumour cell molecular profiling in BRAF-mutant non-small-cell lung cancer
- Laura Mezquita
- , Marianne Oulhen
- & Françoise Farace
-
Article |
TSLP enhances progestin response in endometrial cancer via androgen receptor signal pathway
- Mu Lv
- , Yuan Xu
- & Hong Liao
-
Article
| Open AccessGenome-wide polygenic risk scores for colorectal cancer have implications for risk-based screening
- Max Tamlander
- , Bradley Jermy
- & Nina Mars
-
Article
| Open AccessTargeting serine/glycine metabolism improves radiotherapy response in non-small cell lung cancer
- Anaís Sánchez-Castillo
- , Elien Heylen
- & Kim R. Kampen
-
Article |
PTEN-restoration abrogates brain colonisation and perivascular niche invasion by melanoma cells
- Sarah Wang
- , Caroline P. Riedstra
- & Andrew C. Dudley
-
Article |
Low blood level of tumour suppressor miR-5193 as a target of immunotherapy to PD-L1 in gastric cancer
- Hajime Kamiya
- , Shuhei Komatsu
- & Eigo Otsuji
-
Article
| Open AccessCancer predisposition signaling in Beckwith-Wiedemann Syndrome drives Wilms tumor development
- Snehal Nirgude
- , Natali S. Sobel Naveh
- & Jennifer M. Kalish
-
Article |
Enhanced antitumour response of gold nanostar-mediated photothermal therapy in combination with immunotherapy in a mouse model of colon carcinoma
- Hsin-Hua Hsieh
- , Chuan-Lin Chen
- & Chun-Yi Wu
-
Article
| Open AccessNCI10066: a Phase 1/2 study of olaparib in combination with ramucirumab in previously treated metastatic gastric and gastroesophageal junction adenocarcinoma
- Michael Cecchini
- , James M. Cleary
- & Jill Lacy
-
Article |
Tumour-associated macrophages and Schwann cells promote perineural invasion via paracrine loop in pancreatic ductal adenocarcinoma
- Bin Zhang
- , Xiaofeng Guo
- & Quanbo Zhou
-
Article
| Open AccessCHARIOT: a phase I study of berzosertib with chemoradiotherapy in oesophageal and other solid cancers using time to event continual reassessment method
- S. R. Javed
- , S. Lord
- & M. A. Hawkins
-
Article
| Open AccessStroma AReactive Invasion Front Areas (SARIFA) improves prognostic risk stratification of perioperative chemotherapy treated oesophagogastric cancer patients from the MAGIC and the ST03 trial
- Bianca Grosser
- , Jake Emmerson
- & Heike I. Grabsch
-
Article
| Open AccessPAK inhibitor FRAX486 decreases the metastatic potential of triple-negative breast cancer cells by blocking autophagy
- Liang Lyu
- , Haiyan Li
- & Huihui Li
-
Article |
MET exon 14 skipping mutation drives cancer progression and recurrence via activation of SMAD2 signalling
- Qiaoyan Liang
- , Yajun Hu
- & Bing Zhao
-
Article |
Factors associated with the melanoma diagnostic interval in Ontario, Canada: a population-based study
- Meaghan E. Mavor
- , Timothy P. Hanna
- & Patti A. Groome
-
Article |
Primary resistance to immunotherapy in patients with a dMMR/MSI metastatic gastrointestinal cancer: who is at risk? An AGEO real-world study
- Clémence Flecchia
- , Edouard Auclin
- & Julien Taieb
-
Article
| Open AccessUrine-derived bladder cancer organoids (urinoids) as a tool for cancer longitudinal response monitoring and therapy adaptation
- Bastiaan J. Viergever
- , Daniëlle A. E. Raats
- & Richard P. Meijer
-
Correspondence |
Tumour budding in head and neck cancer: what have we learnt and the next steps towards clinical implementation
- Alhadi Almangush
- , Antti A. Mäkitie
- & Ilmo Leivo
-
Article
| Open AccessCompartment-specific multiomic profiling identifies SRC and GNAS as candidate drivers of epithelial-to-mesenchymal transition in ovarian carcinosarcoma
- C. Simon Herrington
- , Ailsa J. Oswald
- & Robert L. Hollis
-
Article |
Periostin–TGF-β feedforward loop contributes to tumour-stroma crosstalk in liver metastatic outgrowth of colorectal cancer
- Bin Liu
- , Tiantian Wu
- & Gaoliang Ouyang
-
Article
| Open AccessDiscordance between GCIG CA-125 progression and RECIST progression in the CALYPSO trial of patients with platinum-sensitive recurrent ovarian cancer
- Danka Sinikovic Zebic
- , Angelina Tjokrowidjaja
- & Chee Khoon Lee
-
Article
| Open AccessCharacterisation of FLT3 alterations in childhood acute lymphoblastic leukaemia
- Angela Gutierrez-Camino
- , Chantal Richer
- & Daniel Sinnett
-
Article |
Stromal localization of inactive CD8+ T cells in metastatic mismatch repair deficient colorectal cancer
- Emre Küçükköse
- , Matthijs J. D. Baars
- & Yvonne Vercoulen
-
Article
| Open AccessOpposing roles by KRAS and BRAF mutation on immune cell infiltration in colorectal cancer – possible implications for immunotherapy
- Sofia Edin
- , Björn Gylling
- & Richard Palmqvist
-
Article |
Low-dose metronomic cisplatin as an antiangiogenic and anti-inflammatory strategy for cancer
- Hiroshi Kikuchi
- , Nako Maishi
- & Kyoko Hida
-
Article |
Downregulation of N4-acetylcytidine modification in myeloid cells attenuates immunotherapy and exacerbates hepatocellular carcinoma progression
- Nan Xu
- , Jianyong Zhuo
- & Qiang Wei
-
Article |
Risk-reducing mastectomy and breast cancer mortality in women with a BRCA1 or BRCA2 pathogenic variant: an international analysis
- Kelly Metcalfe
- , Tomasz Huzarski
- & Stephanie Cohen
-
Article
| Open AccessHealth benefits and harms of mammography screening in older women (75+ years)—a systematic review
- Erin Mathieu
- , Naomi Noguchi
- & Nehmat Houssami
-
Article |
EEF1A2 promotes HIF1A mediated breast cancer angiogenesis in normoxia and participates in a positive feedback loop with HIF1A in hypoxia
- Saket Awadhesbhai Patel
- , Md. Khurshidul Hassan
- & Manjusha Dixit
-
Correspondence |
Comment on “Development and validation of a multivariable model for prediction of malignant transformation and recurrence of oral epithelial dysplasia”
- Gargi Sarode
- & Sachin C. Sarode
-
Article |
Dexamethasone-sparing on days 2–4 with combined palonosetron, neurokinin-1 receptor antagonist, and olanzapine in cisplatin: a randomized phase III trial (SPARED Trial)
- Hiroko Minatogawa
- , Naoki Izawa
- & Takako Eguchi Nakajima
-
Article
| Open AccessCirculating tumour cells and PD-L1-positive small extracellular vesicles: the liquid biopsy combination for prognostic information in patients with metastatic non-small cell lung cancer
- Zahra Eslami-S
- , Luis Enrique Cortés-Hernández
- & Catherine Alix-Panabières
-
Article |
APC/PIK3CA mutations and β-catenin status predict tankyrase inhibitor sensitivity of patient-derived colorectal cancer cells
- Mingjue Chen
- , Tetsuo Mashima
- & Hiroyuki Seimiya
-
Article |
Enlarged tumour-draining lymph node with immune-activated profile predict favourable survival in non-metastatic colorectal cancer
- Xu Guan
- , Pu Cheng
- & Xishan Wang
-
Article
| Open AccessIntegrating a microRNA signature as a liquid biopsy-based tool for the early diagnosis and prediction of potential therapeutic targets in pancreatic cancer
- Wenjie Shi
- , Thomas Wartmann
- & Ulf D. Kahlert
-
Review Article |
Acquired copy number variation in prostate tumours: a review of common somatic copy number alterations, how they are formed and their clinical utility
- Dannielle E. O’Malley
- , Kelsie Raspin
- & Liesel M. FitzGerald
-
Article |
Resistance to osimertinib in advanced EGFR-mutated NSCLC: a prospective study of molecular genotyping on tissue and liquid biopsies
- A. Leonetti
- , M. Verzè
- & M. Tiseo
Browse narrower subjects
- Biochemistry
- Biological techniques
- Biophysics
- Biotechnology
- Cancer
- Cell biology
- Chemical biology
- Computational biology and bioinformatics
- Developmental biology
- Drug discovery
- Ecology
- Evolution
- Genetics
- Immunology
- Microbiology
- Molecular biology
- Neuroscience
- Physiology
- Plant sciences
- Psychology
- Stem cells
- Structural biology
- Systems biology
- Zoology