Research Highlights |
Featured
-
-
Letter |
An oxygenase that forms and deoxygenates toxic epoxide
The epoxidase PaaABCE, which converts phenylacetyl-CoA into its ring-1,2-epoxide, is shown to be also able to mediate the NADPH-dependent removal of that epoxide, ensuring that the intracellular concentrations of the toxic epoxide does not exceed a certain ‘acceptable’ concentration.
- Robin Teufel
- , Thorsten Friedrich
- & Georg Fuchs
-
Article |
Type VI secretion requires a dynamic contractile phage tail-like structure
Microscopy reveals the dynamics of the type VI secretion system of Vibrio cholerae and its structural and functional resemblance to the contractile tail sheath of bacteriophages.
- M. Basler
- , M. Pilhofer
- & J. J. Mekalanos
-
News & Views |
A sweet way of sensing danger
Cells can destroy invading bacteria through a digestive process called autophagy. A study finds that sugar molecules, exposed by bacterial damage to the cell's membrane, can trigger this process. See Letter p.414
- Ju Huang
- & John H. Brumell
-
Review Article |
RNA-guided genetic silencing systems in bacteria and archaea
- Blake Wiedenheft
- , Samuel H. Sternberg
- & Jennifer A. Doudna
-
Article |
Structural basis for iron piracy by pathogenic Neisseria
Structural analysis reveals the iron scavenging mechanism used by Neisseria species, involving TbpA and TbpB proteins, and sheds light on how human transferrin is specifically targeted.
- Nicholas Noinaj
- , Nicole C. Easley
- & Susan K. Buchanan
-
Research Highlights |
Manganese fights deadly toxin
-
News |
Study challenges existence of arsenic-based life
Open-science advocates fail to reproduce controversial findings.
- Erika Check Hayden
-
Research Highlights |
Bacterial weapon: inflammation
-
News & Views |
Bacteria collaborate to sense arsenic
A method developed to allow rapid communication between bacterial cells across long distances enables the cells to detect arsenic collectively, and to report it as an oscillatory output. See Article p.39
- Christopher A. Voigt
-
Research Highlights |
The first microtubules
-
Research Highlights |
Splitting a bacterial magnet
-
News |
How bacteria break a magnet
A magnetosensing bacterium bends its internal magnet to weaken it before cell division.
- Ewen Callaway
-
Research Highlights |
Bacteria pass through plants
-
News |
Deconstructing dental plaque
Imaging technique could show how dozens of bacteria interact in the human mouth.
- Monya Baker
-
News |
Septin proteins take bacterial prisoners
A cellular defence against microbial pathogens holds therapeutic potential.
- Amanda Mascarelli
-
News |
Antibiotic resistance marching across Europe
Multimillion-euro research initiative set up to address the problem.
- Natasha Gilbert
-
Letter |
Intermediates in the transformation of phosphonates to phosphate by bacteria
NMR spectroscopy is used to elucidate the intermediates in the bacterial transformation of alkylphosphonates to phosphate, showing that the essential bond cleavage occurs in a radical-based reaction in the presence of S-adenosyl-l-methionine.
- Siddhesh S. Kamat
- , Howard J. Williams
- & Frank M. Raushel
-
Letter |
Ecology drives a global network of gene exchange connecting the human microbiome
- Chris S. Smillie
- , Mark B. Smith
- & Eric J. Alm
-
News & Views |
Plague's progress
The Black Death was one of the most devastating pandemics in human history. The first complete genome sequence of the causative Yersinia pestis bacterium provides a fresh perspective on plague evolution. See Letter p.506
- Edward C. Holmes
-
News |
Friendly bacteria move in mysterious ways
Probiotic yoghurts have only a small effect on gut bacteria.
- Ed Yong
-
News |
No quick fix for Haiti cholera
As outbreak enters its second year, relief bodies move to roll out vaccine for the first time.
- Declan Butler
-
Research Highlights |
How a bacterium grabs the gut
-
Letter |
Molecular mechanism of anaerobic ammonium oxidation
- Boran Kartal
- , Wouter J. Maalcke
- & Marc Strous
-
-
Letter |
STING is a direct innate immune sensor of cyclic di-GMP
- Dara L. Burdette
- , Kathryn M. Monroe
- & Russell E. Vance
-
News |
How microbes train our immune system
Gut bacteria coax T cells to see them as friends.
- Alla Katsnelson
-
Letter |
Structures of the RNA-guided surveillance complex from a bacterial immune system
- Blake Wiedenheft
- , Gabriel C. Lander
- & Eva Nogales
-
Letter |
The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus
- Yue Zhao
- , Jieling Yang
- & Feng Shao
-
News |
Electrified bacterial filaments zap uranium
Mechanism by which microbes scrub radioactive contamination revealed.
- Lee Sweetlove
-
Letter |
Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity
- Eric M. Kofoed
- & Russell E. Vance
-
News |
Bacterium offers way to control dengue fever
Wolbachia strain halts virus in mosquitoes.
- Natasha Gilbert
-
Letter |
Evidence for several waves of global transmission in the seventh cholera pandemic
- Ankur Mutreja
- , Dong Wook Kim
- & Gordon Dougan
-
Letter |
Successful establishment of Wolbachia in Aedes populations to suppress dengue transmission
- A. A. Hoffmann
- , B. L. Montgomery
- & S. L. O’Neill
-
Letter |
The wMel Wolbachia strain blocks dengue and invades caged Aedes aegypti populations
- T. Walker
- , P. H. Johnson
- & A. A. Hoffmann
-
Research Highlights |
Russian doll-style symbiosis
-
Letter |
N2O binding at a [4Cu:2S] copper–sulphur cluster in nitrous oxide reductase
- Anja Pomowski
- , Walter G. Zumft
- & Oliver Einsle
-
News & Views |
Hydrogen for dinner
The vast array of bacterium–animal symbioses at deep-sea hydrothermal vents was thought to be fuelled by just two chemicals. A study of one such symbiosis in its environmental context reveals a third energy source. See Article p. 176
- Victoria J. Orphan
- & Tori M. Hoehler
-
Article |
Hydrogen is an energy source for hydrothermal vent symbioses
- Jillian M. Petersen
- , Frank U. Zielinski
- & Nicole Dubilier
-
News |
Open research casts doubt on arsenic life
Blog documenting quest to replicate finding could be taste of things to come.
- Erika Check Hayden
-
-
Research Highlights |
Bacteria whip around corners
-
News |
E. coli outbreak strain in genome race
Sequence data reveal pathogen's deadly origins.
- Marian Turner
-
Research Highlights |
Bacteria 'blink' to expel molecules
-
News & Views |
Molecular syringes scratch the surface
New data suggest that the most recently discovered class of bacterial 'molecular syringes' inject proteins only across the outer membrane of target cells during interbacterial competition. See Article p.343
- Peggy Cotter
-
Article |
Type VI secretion delivers bacteriolytic effectors to target cells
- Alistair B. Russell
- , Rachel D. Hood
- & Joseph D. Mougous
-
-
Research Highlights |
A key for bacterial entry
-
News |
Calcified clue to ancient photosynthesis
Mat of microbes contains calcium carbonate that could only have formed through photosynthesis.
- Katharine Sanderson
-
Browse broader subjects
Browse narrower subjects
- Bacterial development
- Bacterial evolution
- Bacterial genetics
- Bacterial genomics
- Bacterial host response
- Bacterial immune evasion
- Bacterial pathogenesis
- Bacterial physiology
- Bacterial secretion
- Bacterial structural biology
- Bacterial synthetic biology
- Bacterial systems biology
- Bacterial techniques and applications
- Bacterial toxins
- Bacterial transcription
- Cellular microbiology
- Infectious-disease epidemiology
- Marine microbiology
- Metagenomics
- Symbiosis