Featured
-
-
Review |
Herpesvirus microRNAs for use in gene therapy immune-evasion strategies
- S T F Bots
- & R C Hoeben
-
Original Article |
Development of potent class II transactivator gene delivery systems capable of inducing de novo MHC II expression in human cells, in vitro and ex vivo
- M L Palma
- , P Duangkhae
- & E T A Marques
-
Original Article |
AAV9-mediated engineering of autotransplanted kidney of non-human primates
- S Tomasoni
- , P Trionfini
- & A Benigni
-
Short Communication |
Neutralizing antibodies against adeno-associated viruses in Sjögren’s patients: implications for gene therapy
- A Corden
- , B Handelman
- & J A Chiorini
-
Original Article
| Open AccessBalanced secretion of anti-CEA × anti-CD3 diabody chains using the 2A self-cleaving peptide maximizes diabody assembly and tumor-specific cytotoxicity
- K Mølgaard
- , M Compte
- & L Alvarez-Vallina
-
Original Article |
Adenovirus-mediated Foxp3 expression in lung epithelial cells ameliorates acute radiation-induced pneumonitis in mice
- D Shin
- , G Lee
- & H Bae
-
Original Article
| Open AccessActivation of myeloid and endothelial cells by CD40L gene therapy supports T-cell expansion and migration into the tumor microenvironment
- E Eriksson
- , R Moreno
- & A Loskog
-
Original Article |
Prime-boost using separate oncolytic viruses in combination with checkpoint blockade improves anti-tumour therapy
- E Ilett
- , T Kottke
- & R Vile
-
Original Article |
Immune effect and safety evaluation of vaccine prepared by dendritic cells modified by rAAV-carrying BCSG1 gene
- W-H Wang
- , C-H Zhou
- & W Zhang
-
Original Article |
Local gene therapy with indoleamine 2,3-dioxygenase protects against development of transplant vasculopathy in chronic kidney transplant dysfunction
- D Vavrincova-Yaghi
- , L E Deelman
- & M Sandovici
-
Original Article |
T- and B-cell responses to multivalent prime-boost DNA and viral vectored vaccine combinations against hepatitis C virus in non-human primates
- C S Rollier
- , E J Verschoor
- & J L Heeney
-
Original Article |
A dual chain chimeric antigen receptor (CAR) in the native antibody format for targeting immune cells towards cancer cells without the need of an scFv
- E Faitschuk
- , V Nagy
- & H Abken
-
Original Article |
Optimized human CYP4B1 in combination with the alkylator prodrug 4-ipomeanol serves as a novel suicide gene system for adoptive T-cell therapies
- K Roellecke
- , E L Virts
- & H Hanenberg
-
Short Communication |
Reduced retinal transduction and enhanced transgene-directed immunogenicity with intravitreal delivery of rAAV following posterior vitrectomy in dogs
- R F Boyd
- , S L Boye
- & J T Bartoe
-
Original Article |
Effects of transgene expression level per cell in mice livers on induction of transgene-specific immune responses after hydrodynamic gene transfer
- Y Yin
- , Y Takahashi
- & Y Takakura
-
Original Article |
The induction of antigen-specific CTL by in situ Ad-REIC gene therapy
- Y Ariyoshi
- , M Watanabe
- & H Kumon
-
Original Article |
Gene transfer of two entry inhibitors protects CD4+ T cell from HIV-1 infection in humanized mice
- N Y Petit
- , C Baillou
- & G Marodon
-
Original Article |
Lymphopoiesis in transgenic mice over-expressing Artemis
- P Rivera-Munoz
- , V Abramowski
- & J-P de Villartay
-
Original Article |
Intradermal delivery of DNA encoding HCV NS3 and perforin elicits robust cell-mediated immunity in mice and pigs
- B Grubor-Bauk
- , W Yu
- & E J Gowans
-
Short Communication |
Slow AAV2 clearance from the brain of nonhuman primates and anti-capsid immune response
- L Samaranch
- , P Hadaczek
- & K S Bankiewicz
-
Short Communication |
Development of operational immunologic tolerance with neonatal gene transfer in nonhuman primates: preliminary studies
- D S Tai
- , C Hu
- & G S Lipshutz
-
Short Communication |
Coexpression of human perforin improves yeast-mediated delivery of DNA and mRNA to mammalian antigen-presenting cells
- B Walch-Rückheim
- , R Kiefer
- & F Breinig
-
Original Article |
Mesothelin-specific cell-based vaccine generates antigen-specific immunity and potent antitumor effects by combining with IL-12 immunomodulator
- M-C Chang
- , Y-L Chen
- & W-F Cheng
-
Original Article |
Recombinant AAV-mediated in vivo long-term expression and antitumour activity of an anti-ganglioside GM3(Neu5Gc) antibody
- G M Piperno
- , A López-Requena
- & M Cesco-Gaspere
-
Original Article |
Inhalation of recombinant adenovirus expressing granulysin protects mice infected with Mycobacterium tuberculosis
- J Ma
- , J Lu
- & X Fan
-
Original Article |
Gene therapy with neurogenin3, betacellulin and SOCS1 reverses diabetes in NOD mice
- R Li
- , E Buras
- & L Chan
-
Original Article |
The spread of adenoviral vectors to central nervous system through pathway of cochlea in mimetic aging and young rats
- X Chen
- , X Zhao
- & W Kong
-
Original Article |
Enhanced T-cell activation and differentiation in lymphocytes from transgenic mice expressing ubiquitination-resistant 2KR LAT molecules
- A B Rodriguez-Peña
- , J Gomez-Rodriguez
- & L Balagopalan
-
-
Original Article
| Open AccessLentivirus-induced ‘Smart’ dendritic cells: Pharmacodynamics and GMP-compliant production for immunotherapy against TRP2-positive melanoma
- B S Sundarasetty
- , L Chan
- & R Stripecke
-
Original Article |
B7H6-specific chimeric antigen receptors lead to tumor elimination and host antitumor immunity
- M-R Wu
- , T Zhang
- & C L Sentman
-
Original Article |
Antigen design enhances the immunogenicity of Semliki Forest virus-based therapeutic human papillomavirus vaccines
- P P Ip
- , A Boerma
- & T Daemen
-
Short Communication |
β-Cell-targeted blockage of PD1 and CTLA4 pathways prevents development of autoimmune diabetes and acute allogeneic islets rejection
- M M El Khatib
- , T Sakuma
- & Y Ikeda
-
Short Communication |
A new method to monitor antigen-specific CD8+ T cells, avoiding additional target cells and the restriction to human leukocyte antigen haplotype
- S Prommersberger
- , S Höfflin
- & J Dörrie
-
Original Article |
Tolerance of activated pathogenic CD4+ T cells by transcriptional targeting of dendritic cells
- B de Andrade Pereira
- , M Ackermann
- & C Fraefel
-
Original Article |
Vpx-containing dendritic cell vaccine induces CTLs and reactivates latent HIV-1 in vitro
- T D Norton
- , E A Miller
- & N R Landau
-
Original Article |
γ134.5-deleted HSV-1-expressing human cytomegalovirus IRS1 gene kills human glioblastoma cells as efficiently as wild-type HSV-1 in normoxia or hypoxia
- G K Friedman
- , L Nan
- & G Y Gillespie
-
Short Communication |
AAVrh.10 immunogenicity in mice and humans. Relevance of antibody cross-reactivity in human gene therapy
- R Thwaite
- , G Pagès
- & A Bosch
-
Original Article |
Prevention of hepatitis C virus infection by adoptive allogeneic immunotherapy using suicide gene-modified lymphocytes: an in vitro proof-of-concept
- C Leboeuf
- , J Roser-Schilder
- & E Robinet
-
Original Article |
Rapid outer-surface protein C DNA tattoo vaccination protects against Borrelia afzelii infection
- A Wagemakers
- , L M K Mason
- & J W R Hovius
-
Original Article
| Open AccessIntramuscular delivery of heterodimeric IL-15 DNA in macaques produces systemic levels of bioactive cytokine inducing proliferation of NK and T cells
- C Bergamaschi
- , V Kulkarni
- & G N Pavlakis
-
Original Article |
DNA vaccine elicits an efficient antitumor response by targeting the mutant Kras in a transgenic mouse lung cancer model
- T-Y Weng
- , M-C Yen
- & M-D Lai
-
Original Article |
Prolonged expression of an anti-HIV-1 gp120 minibody to the female rhesus macaque lower genital tract by AAV gene transfer
- U M Abdel-Motal
- , C Harbison
- & W A Marasco
-
Original Article |
Effects of upregulated indoleamine 2, 3-dioxygenase 1 by interferon γ gene transfer on interferon γ-mediated antitumor activity
- K Watcharanurak
- , L Zang
- & Y Takakura
-
Short Communication
| Open AccessIn vivo targeted delivery of CD40 shRNA to mouse intestinal dendritic cells by oral administration of recombinant Sacchromyces cerevisiae
- L Zhang
- , T Zhang
- & Z Zhang
-
Original Article |
Expression of IL-2 in β cells by AAV8 gene transfer in pre-diabetic NOD mice prevents diabetes through activation of FoxP3-positive regulatory T cells
- R R Flores
- , L Zhou
- & P D Robbins
-
Original Article |
Short noncoding DNA fragments improve the immune potency of electroporation-mediated HBV DNA vaccination
- J Peng
- , S Shi
- & Y Xu
-
Original Article |
Comparative analysis of enzymatically produced novel linear DNA constructs with plasmids for use as DNA vaccines
- A A Walters
- , E Kinnear
- & J S Tregoning
-
Original Article |
Construction and molecular characterization of a T-cell receptor-like antibody and CAR-T cells specific for minor histocompatibility antigen HA-1H
- Y Inaguma
- , Y Akahori
- & Y Akatsuka
Browse broader subjects
Browse narrower subjects
- Adaptive immunity
- Antigen processing and presentation
- Antimicrobial responses
- Applied immunology
- Autoimmunity
- Bone marrow transplantation
- Cell death and immune response
- Chemokines
- Coagulation system
- Complement cascade
- Cytokines
- Gene regulation in immune cells
- Haematopoiesis
- Imaging the immune system
- Immune cell death
- Immune evasion
- Immunogenetics
- Immunological disorders
- Immunotherapy
- Infection
- Infectious diseases
- Inflammation
- Innate immune cells
- Innate immunity
- Lymphatic system
- Lymphocytes
- Lymphoid tissues
- Mucosal immunology
- Neuroimmunology
- Osteoimmunology
- Plant immunology
- Signal transduction
- Translational immunology
- Transplant immunology
- Tumour immunology
- Vaccines