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Original Article |
Enhanced T-cell activation and differentiation in lymphocytes from transgenic mice expressing ubiquitination-resistant 2KR LAT molecules
- A B Rodriguez-Peña
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- & L Balagopalan
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Original Article |
Expression of IL-2 in β cells by AAV8 gene transfer in pre-diabetic NOD mice prevents diabetes through activation of FoxP3-positive regulatory T cells
- R R Flores
- , L Zhou
- & P D Robbins
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Short Communication |
Efficient delivery of lentiviral vectors into resting human CD4 T cells
- X Geng
- , G Doitsh
- & W C Greene
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Original Article |
MULT1E/mIL-12: a novel bifunctional protein for natural killer cell activation
- A Tietje
- , J Li
- & Y Wei
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Short Communication |
Immune escape from NY-ESO-1-specific T-cell therapy via loss of heterozygosity in the MHC
- Z K Klippel
- , J Chou
- & E H Warren
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Original Article |
Modulation of Treg function improves adenovirus vector-mediated gene expression in the airway
- Y Nagai
- , M P Limberis
- & H Zhang
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Mini Review |
Immunotherapy with gene-modified T cells: limiting side effects provides new challenges
- H J Stauss
- & E C Morris
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Original Article
| Open Access
Role of antigen-specific regulatory CD4+CD25+ T cells in tolerance induction after neonatal IP administration of AAV-hF.IX
- Y Shi
- , R Falahati
- & K M L Gaensler
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Original Article |
hIFN-α gene modification augments human natural killer cell line anti-human hepatocellular carcinoma function
- W Jiang
- , C Zhang
- & J Zhang
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Short Communication |
The immunogenicity of virus-derived 2A sequences in immunocompetent individuals
- C Arber
- , H Abhyankar
- & B Savoldo
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Original Article |
Specificity redirection by CAR with human VEGFR-1 affinity endows T lymphocytes with tumor-killing ability and anti-angiogenic potency
- W Wang
- , Y Ma
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Short Communication |
Multi-cistronic vector encoding optimized safety switch for adoptive therapy with T-cell receptor-modified T cells
- M M van Loenen
- , R de Boer
- & M H M Heemskerk
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Short Communication |
Efficient selection of genetically modified human T cells using methotrexate-resistant human dihydrofolate reductase
- M Jonnalagadda
- , C E Brown
- & M C Jensen
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Original Article |
Design of T-cell receptor libraries with diverse binding properties to examine adoptive T-cell responses
- A S Chervin
- , J D Stone
- & D M Kranz
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Short Communication |
Inhibition of TGF-β signaling in genetically engineered tumor antigen-reactive T cells significantly enhances tumor treatment efficacy
- L Zhang
- , Z Yu
- & R A Morgan
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Original Article |
Tolerance to MHC class II disparate allografts through genetic modification of bone marrow
- P T Jindra
- , S Tripathi
- & J Bagley
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Original Article |
Effector memory and central memory NY-ESO-1-specific re-directed T cells for treatment of multiple myeloma
- P C Schuberth
- , G Jakka
- & U Petrausch
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Short Communication |
Ligation of the CD2 co-stimulatory receptor enhances IL-2 production from first-generation chimeric antigen receptor T cells
- E J Cheadle
- , D G Rothwell
- & D E Gilham
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Original Article |
siRNA-mediated silencing of PD-1 ligands enhances tumor-specific human T-cell effector functions
- K Iwamura
- , T Kato
- & H Shiku
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Original Article |
Generating CTLs against the subdominant EBV LMP antigens by transient expression of an A20 inhibitor with EBV LMP proteins in human DCs
- B Hong
- , G Peng
- & X F Huang
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Original Article |
MicroRNA-150-regulated vectors allow lymphocyte-sparing transgene expression in hematopoietic gene therapy
- N Lachmann
- , J Jagielska
- & T Moritz
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Enabling Technologies |
The hyperactive Sleeping Beauty transposase SB100X improves the genetic modification of T cells to express a chimeric antigen receptor
- Z Jin
- , S Maiti
- & L J N Cooper
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Original Article |
CD28 cosignalling does not affect the activation threshold in a chimeric antigen receptor-redirected T-cell attack
- M Chmielewski
- , A A Hombach
- & H Abken
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Review |
Progress and prospects: graft-versus-host disease
- S Mastaglio
- , M T L Stanghellini
- & C Bonini
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Original Article |
Ex vivo culture of chimeric antigen receptor T cells generates functional CD8+ T cells with effector and central memory-like phenotype
- P Neeson
- , A Shin
- & D S Ritchie
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Original Article |
Early exposure of high-dose interleukin-4 to tumor stroma reverses myeloid cell-mediated T-cell suppression
- J Jiang
- , Z Wang
- & Z Qin
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Short Communication |
Cutaneous vaccination using microneedles coated with hepatitis C DNA vaccine
- H S Gill
- , J Söderholm
- & M Sällberg
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Short Communication |
Gene-modified T cells as immunotherapy for multiple myeloma and acute myeloid leukemia expressing the Lewis Y antigen
- S Peinert
- , H M Prince
- & D Hönemann
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Original Article |
Rhadinovirus vector-derived human telomerase reverse transcriptase expression in primary T cells
- T Toptan
- , A Ensser
- & H Fickenscher
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Original Article |
Generation of multi-functional antigen-specific human T-cells by lentiviral TCR gene transfer
- M Perro
- , J Tsang
- & E C Morris
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Original Article |
Vaccination with a potent DNA vaccine targeting B-cell epitopes of hGRP induces prophylactic and therapeutic antitumor activity in vivo
- Lu Yong
- , Zhang Huiyong
- & Wu Jie
Primary T cells for mRNA-mediated immunotoxin delivery
Adoptive immunotherapy with genetically engineered T cells: modification of the IgG1 Fc ‘spacer’ domain in the extracellular moiety of chimeric antigen receptors avoids ‘off-target’ activation and unintended initiation of an innate immune response