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Article
| Open Access
Immunobiology of a rationally-designed AAV2 capsid following intravitreal delivery in mice
- Michael Whitehead
- , Andrew Sage
- & Keith R. Martin
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Article
| Open Access
RapaCaspase-9-based suicide gene applied to the safety of IL-1RAP CAR-T cells
- Lucie Bouquet
- , Elodie Bôle-Richard
- & Marina Deschamps
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Perspective |
Adeno-associated virus vectors and neurotoxicity—lessons from preclinical and human studies
- Daniel Stone
- , Martine Aubert
- & Keith R. Jerome
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Article |
Induced pluripotent stem cell-derived dendritic cell vaccine therapy genetically modified on the ubiquitin-proteasome system
- Shinta Tominaga
- , Toshiyasu Ojima
- & Hiroki Yamaue
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Brief Communication
| Open Access
Glyco-binding domain chimeric antigen receptors as a new option for cancer immunotherapy
- Anna-Katharina Franke
- , Charlotte Wessolowski
- & Kerstin Cornils
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Review Article |
Empowering gene delivery with protein engineering platforms
- Monika Kizerwetter
- , Kevin Pietz
- & Jamie B. Spangler
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Brief Communication |
Potential of an anti-bevacizumab idiotype scFv DNA-based immunization to elicit VEGF-binding antibody response
- Tábata Almeida Silva
- , Rodrigo Barbosa Aguiar
- & Jane Zveiter Moraes
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Article |
Immune profiling of adeno-associated virus response identifies B cell-specific targets that enable vector re-administration in mice
- Maria Chen
- , Boram Kim
- & Omid Veiseh
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Article |
Adeno-associated virus mediated expression of monoclonal antibody MR191 protects mice against Marburg virus and provides long-term expression in sheep
- Amira D. Rghei
- , Laura P. van Lieshout
- & Sarah K. Wootton
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Article
| Open Access
Preclinical assessment of antigen-specific chimeric antigen receptor regulatory T cells for use in solid organ transplantation
- Emma Proics
- , Marion David
- & Céline Dumont
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Article |
Loss of RAGE prevents chronic intermittent hypoxia-induced nonalcoholic fatty liver disease via blockade of NF-кB pathway
- Haoqu Tan
- , Jinfang Hu
- & Wei Bai
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Article |
Development of a cGMP-compliant process to manufacture donor-derived, CD45RA-depleted memory CD19-CAR T cells
- Young-In Kim-Hoehamer
- , Janice M. Riberdy
- & Sheng Zhou
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Article |
Biodistribution and immunity of adenovirus 5/35 and modified vaccinia Ankara vector vaccines against human immunodeficiency virus 1 clade C
- Masaru Shimada
- , Haibin Wang
- & Kenji Okuda
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Article
| Open Access
A short hepatitis C virus NS5A peptide expression by AAV vector modulates human T cell activation and reduces vector immunogenicity
- Winston Colon-Moran
- , Alan Baer
- & Nirjal Bhattarai
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Brief Communication |
Endotoxin contamination in commercially available Cas9 proteins potentially induces T-cell mediated responses
- Vijaya L. Simhadri
- , Joseph R. McGill
- & Zuben E. Sauna
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Article |
Adjuvant properties of IFN-γ and GM-CSF in the scFv6.C4 DNA vaccine against CEA-expressing tumors
- Bianca Ferrarini Zanetti
- , Camila Pontes Ferreira
- & Sang Won Han
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Article
| Open Access
Automated production of CCR5-negative CD4+-T cells in a GMP-compatible, clinical scale for treatment of HIV-positive patients
- Lea Isabell Schwarze
- , Tanja Sonntag
- & Boris Fehse
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Article
| Open Access
CARAMBA: a first-in-human clinical trial with SLAMF7 CAR-T cells prepared by virus-free Sleeping Beauty gene transfer to treat multiple myeloma
- Sabrina Prommersberger
- , Michael Reiser
- & Zoltán Ivics
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Review Article
| Open Access
Current status and perspective of CAR-T and CAR-NK cell therapy trials in Germany
- Nawid Albinger
- , Jessica Hartmann
- & Evelyn Ullrich
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Article
| Open Access
Functional expression of complement factor I following AAV-mediated gene delivery in the retina of mice and human cells
- Anna K. Dreismann
- , Michelle E. McClements
- & Robert E. MacLaren
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Review Article
| Open Access
Cas9-directed immune tolerance in humans—a model to evaluate regulatory T cells in gene therapy?
- Dimitrios Laurin Wagner
- , Lena Peter
- & Michael Schmueck-Henneresse
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Comment
| Open Access
From macrophage biology to macrophage-based cellular immunotherapies
- Elvira Mass
- & Nico Lachmann
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Article
| Open Access
Targeted multi-epitope switching enables straightforward positive/negative selection of CAR T cells
- Laura Mosti
- , Lukas M. Langner
- & Toni Cathomen
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Brief Communication |
Host antibacterial defense of 6–10 Gy γ-irradiated mice subjected to lentiviral vector-based Gas5 gene therapy
- Ichiaki Ito
- , Bradford D. Loucas
- & Fujio Suzuki
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Review Article |
Effects of oncolytic viruses and viral vectors on immunity in glioblastoma
- Penghao Liu
- , Yaning Wang
- & Yu Wang
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Article |
Antitumor effects of IL-12 and GM-CSF co-expressed in an engineered oncolytic HSV-1
- Kyoung-Ju Kim
- , Dahye Moon
- & Kyung-Ju Choi
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Review Article |
Self-amplifying RNA vaccines for infectious diseases
- Kristie Bloom
- , Fiona van den Berg
- & Patrick Arbuthnot
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Review Article
| Open Access
Antiviral immunity and nucleic acid sensing in haematopoietic stem cell gene engineering
- Francesco Piras
- & Anna Kajaste-Rudnitski
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Article |
Neutralisation of adeno-associated virus transduction by human vitreous humour
- Sławomir Andrzejewski
- , Peter M. Moyle
- & Christopher J. Layton
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Brief Communication
| Open Access
Lentiviral gene therapy rescues p47phox chronic granulomatous disease and the ability to fight Salmonella infection in mice
- Andrea Schejtman
- , Walmir Cutrim Aragão-Filho
- & Giorgia Santilli
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Brief Communication |
‘Mini’ U6 Pol III promoter exhibits nucleosome redundancy and supports multiplexed coupling of CRISPR/Cas9 effects
- Roland Preece
- , Christos Georgiadis
- & Waseem Qasim
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Article |
Transposon-mediated generation of CAR-T cells shows efficient anti B-cell leukemia response after ex vivo expansion
- Leonardo Chicaybam
- , Luiza Abdo
- & Martín Hernán Bonamino
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Article
| Open Access
Inside out: optimization of lipid nanoparticle formulations for exterior complexation and in vivo delivery of saRNA
- Anna K. Blakney
- , Paul F. McKay
- & Robin J. Shattock
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Article |
Bat adeno-associated viruses as gene therapy vectors with the potential to evade human neutralizing antibodies
- Ya Li
- , Jialu Li
- & Lin Yang
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Comment |
Magic realism: a Latin American paradigm for stem cell research & development?
- Maroun Khoury
- & Fernando E. Figueroa
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Article |
Adeno-associated virus neutralising antibodies in type 1 diabetes mellitus
- Slawomir Andrzejewski
- , Aparna Murali
- & Christopher J. Layton
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Article
| Open Access
Immunosuppression overcomes insulin- and vector-specific immune responses that limit efficacy of AAV2/8-mediated insulin gene therapy in NOD mice
- Asha Recino
- , Shu Uin Gan
- & Maja Wallberg
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Article
| Open Access
Characterization of abscopal effects of intratumoral electroporation-mediated IL-12 gene therapy
- Anandaroop Mukhopadhyay
- , Jocelyn Wright
- & Robert H. Pierce
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Article |
Scaffold-mediated delivery for non-viral mRNA vaccines
- Ruying Chen
- , Hong Zhang
- & James D. Bryers
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Article |
In vivo delivery of pPERDBY to BALB/c mice by LacVax® DNA-I and comparison of elicited immune response with conventional immunization methods
- Bhrugu Yagnik
- , Drashya Sharma
- & Priti Desai
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Comment
| Open Access
Driving cars to the clinic for solid tumors
- Mauro Castellarin
- , Keisuke Watanabe
- & Avery D. Posey Jr.
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Comment
| Open AccessFludarabine and neurotoxicity in engineered T-cell therapy
- Kate L. Lowe
- , Crystal L. Mackall
- & Gwendolyn Binder
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Article |
Excessive activated T-cell proliferation after anti-CD19 CAR T-cell therapy
- Wen-ying Zhang
- , Yang Liu
- & Wei-dong Han
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Original Article
| Open Access
Adipose tissue: a new target for electroporation-enhanced DNA vaccines
- P D Fisher
- , C J Brambila
- & K E Broderick
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Original Article |
Primary T cells for mRNA-mediated immunotoxin delivery
- R Eggers
- , A Philippi
- & M J Schmitt
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Short Communication |
Antigen-presenting cell-targeted lentiviral vectors do not support the development of productive T-cell effector responses: implications for in vivo targeted vaccine delivery
- C Goyvaerts
- , Y De Vlaeminck
- & K Breckpot
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Original Article |
Effect of IL-1β, TNF-α and IGF-1 on trans-endothelial passage of synthetic vectors through an in vitro vascular endothelial barrier of striated muscle
- J P Gomez
- , C Gonçalves
- & P Midoux
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Original Article |
Coinjection of IL2 DNA enhances E7-specific antitumor immunity elicited by intravaginal therapeutic HPV DNA vaccination with electroporation
- Y Sun
- , S Peng
- & C-F Hung
Advancing rare disease treatment: EMA’s decade-long insights into engineered adoptive cell therapy for rare cancers and orphan designationBrowse broader subjects
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