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IL-24 improves efficacy of CAR-T cell therapy by targeting stemness of tumor cells
- Kai Zhang
- , Wenhao Hu
- & Yi Zhang
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Germline predictors for bevacizumab induced hypertensive crisis in ECOG-ACRIN 5103 and BEATRICE
- Fei Shen
- , Guanglong Jiang
- & Bryan P. Schneider
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| Open AccessUnraveling the impact of cancer-associated fibroblasts on hypovascular pancreatic neuroendocrine tumors
- Ting-Yu Lai
- , Tsai-Chen Chiang
- & Wen-Hwa Lee
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| Open AccessAHRR and SFRP2 in primary versus recurrent high-grade serous ovarian carcinoma and their prognostic implication
- Nanna Monjé
- , Mihnea P. Dragomir
- & Eliane T. Taube
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| Open AccessSynergistic induction of tertiary lymphoid structures by chemoimmunotherapy in bladder cancer
- Lu Zhang
- , Ruiyun Zhang
- & Jinhai Fan
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| Open AccessSerum NY-ESO-1 antibody as a predictive biomarker for postoperative recurrence of gastric cancer: a multicenter prospective observational study
- Takuro Saito
- , Yukinori Kurokawa
- & Yuichiro Doki
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| Open AccessLong-term activation of anti-tumor immunity in pancreatic cancer by a p53-expressing telomerase-specific oncolytic adenovirus
- Masashi Hashimoto
- , Shinji Kuroda
- & Toshiyoshi Fujiwara
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| Open AccessAntibodies toward Na+,HCO3–-cotransporter NBCn1/SLC4A7 block net acid extrusion and cause pH-dependent growth inhibition and apoptosis in breast cancer
- Trine V. Axelsen
- , Claus Olesen
- & Ebbe Boedtkjer
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| Open AccessA UK prospective multicentre decision impact, decision conflict and economic evaluation of the 21-gene assay in women with node+ve, hormone receptor+ve, HER2-ve breast cancer
- Simon Holt
- , Mark Verrill
- & Saira Khawaja
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| Open AccessImmune evasion in lung metastasis of leiomyosarcoma: upregulation of EPCAM inhibits CD8+ T cell infiltration
- Masaya Kanahori
- , Eijiro Shimada
- & Yasuharu Nakashima
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| Open AccessInhibition of Aurora B kinase (AURKB) enhances the effectiveness of 5-fluorouracil chemotherapy against colorectal cancer cells
- Esha T. Shah
- , Christopher Molloy
- & Mark N. Adams
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| Open AccessIdentification of novel molecular subtypes to improve the classification framework of nasopharyngeal carcinoma
- Wanzun Lin
- , Xiaochuan Chen
- & Sufang Qiu
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| Open AccessFarnesyl-transferase inhibitors show synergistic anticancer effects in combination with novel KRAS-G12C inhibitors
- Marcell Baranyi
- , Eszter Molnár
- & József Tímár
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wMKL: multi-omics data integration enables novel cancer subtype identification via weight-boosted multi-kernel learning
- Hongyan Cao
- , Congcong Jia
- & Yuehua Cui
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Exposure-response relationship of cabozantinib in patients with metastatic renal cell carcinoma treated in routine care
- Benoit Blanchet
- , Alexandre Xu-Vuilard
- & Yann-Alexandre Vano
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| Open AccessMetabolic heterogeneity affects trastuzumab response and survival in HER2-positive advanced gastric cancer
- Jun Wang
- , Na Sun
- & Axel Walch
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| Open AccessIntegrated genomic and transcriptomic analysis reveals the activation of PI3K signaling pathway in HPV-independent cervical cancers
- Yi Wang
- , Misi He
- & Huijuan Yang
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| Open AccessResults of a randomised Phase II trial of olaparib, chemotherapy or olaparib and cediranib in patients with platinum-resistant ovarian cancer
- Shibani Nicum
- , Naomi McGregor
- & Anita Mansouri
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Predicting 5-year recurrence risk in colorectal cancer: development and validation of a histology-based deep learning approach
- Han Xiao
- , Zongpeng Weng
- & Sui Peng
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| Open AccessRisk of subsequent gliomas and meningiomas among 69,460 5-year survivors of childhood and adolescent cancer in Europe: the PanCareSurFup study
- Emma J. Heymer
- , Michael M. Hawkins
- & Raoul C. Reulen
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Comparison of the ADNEX and ROMA risk prediction models for the diagnosis of ovarian cancer: a multicentre external validation in patients who underwent surgery
- Chiara Landolfo
- , Jolien Ceusters
- & Ben Van Calster
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Time-series blood cytokine profiles correlate with treatment responses in triple-negative breast cancer patients
- Don Pietro Saldajeno
- , Shinpei Kawaoka
- & Masakazu Toi
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| Open AccessRedox signalling regulates breast cancer metastasis via phenotypic and metabolic reprogramming due to p63 activation by HIF1α
- Zuen Ren
- , Malindrie Dharmaratne
- & Rachel B. Hazan
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Circulating small extracellular vesicle-based miRNA classifier for follicular thyroid carcinoma: a diagnostic study
- Genpeng Li
- , Hongke Wang
- & Jianyong Lei
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Tumor-associated neutrophils suppress CD8+ T cell immunity in urothelial bladder carcinoma through the COX-2/PGE2/IDO1 Axis
- Yi Ouyang
- , Wenlong Zhong
- & Tianxin Lin
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| Open AccessSoluble lymphocyte activation gene-3 (sLAG3) and CD4/CD8 ratio dynamics as predictive biomarkers in patients undergoing immune checkpoint blockade for solid malignancies
- Joao Gorgulho
- , Christoph Roderburg
- & Tom Luedde
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| Open AccessGSTM3 enhances radiosensitivity of nasopharyngeal carcinoma by promoting radiation-induced ferroptosis through USP14/FASN axis and GPX4
- Yuting Chen
- , Yuanyuan Feng
- & Longmei Cai
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Mitochondrial DNA copy number plays opposing roles in T-lymphocyte infiltration of colorectal cancer based on mismatch repair status: new directions for immunotherapy?
- Mian Chen
- , Huashan Liu
- & Liang Huang
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| Open AccessPeroxisomal β-oxidation enzyme, DECR2, regulates lipid metabolism and promotes treatment resistance in advanced prostate cancer
- Chui Yan Mah
- , An Dieu Trang Nguyen
- & Lisa M. Butler
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| Open AccessIntegrative score based on CDK6, PD-L1 and TMB predicts response to platinum-based chemotherapy and PD-1/PD-L1 blockade in muscle-invasive bladder cancer
- Xiaohe Su
- , Kaifeng Jin
- & Jiejie Xu
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| Open AccessGlioblastoma biomarkers in urinary extracellular vesicles reveal the potential for a ‘liquid gold’ biopsy
- Susannah M. Hallal
- , Ágota Tűzesi
- & Kimberley L. Alexander
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Minimum latency effects for cancer associated with exposures to radiation or other carcinogens
- Mark P. Little
- , Markus Eidemüller
- & A. Iulian Apostoaei
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| Open AccessPhase 1 study of high-dose DFMO, celecoxib, cyclophosphamide and topotecan for patients with relapsed neuroblastoma: a New Approaches to Neuroblastoma Therapy trial
- Michael D. Hogarty
- , David S. Ziegler
- & Araz Marachelian
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| Open AccessMed23 deficiency reprograms the tumor microenvironment to promote lung tumorigenesis
- Xiaobo Fu
- , Siming Liu
- & Gang Wang
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Dynamic nature of BRAF or KRAS p.G12C mutations in second-line therapy for advanced colorectal cancer patients: do early and late effects exist?
- Débora Contreras-Toledo
- , Paula Jiménez-Fonseca
- & Alberto Carmona-Bayonas
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EGLN3 attenuates gastric cancer cell malignant characteristics by inhibiting JMJD8/NF-κB signalling activation independent of hydroxylase activity
- Fenglin Cai
- , Xiuding Yang
- & Jingyu Deng
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The clinical implication and translational research of OSCC differentiation
- Qianhui Shang
- , Yuchen Jiang
- & Hao Xu
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TRIM21/USP15 balances ACSL4 stability and the imatinib resistance of gastrointestinal stromal tumors
- Zhiwei Cui
- , Haoyu Sun
- & Hao Xu
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p4EBP1 staining predicts outcome in ER-positive endocrine-resistant metastatic breast cancer patients treated with everolimus and exemestane
- Hélène Vanacker
- , Isabelle Treilleux
- & Thomas Bachelot
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| Open AccessResistance to BRAF inhibition explored through single circulating tumour cell molecular profiling in BRAF-mutant non-small-cell lung cancer
- Laura Mezquita
- , Marianne Oulhen
- & Françoise Farace
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TSLP enhances progestin response in endometrial cancer via androgen receptor signal pathway
- Mu Lv
- , Yuan Xu
- & Hong Liao
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| Open AccessGenome-wide polygenic risk scores for colorectal cancer have implications for risk-based screening
- Max Tamlander
- , Bradley Jermy
- & Nina Mars
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| Open AccessTargeting serine/glycine metabolism improves radiotherapy response in non-small cell lung cancer
- Anaís Sánchez-Castillo
- , Elien Heylen
- & Kim R. Kampen
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PTEN-restoration abrogates brain colonisation and perivascular niche invasion by melanoma cells
- Sarah Wang
- , Caroline P. Riedstra
- & Andrew C. Dudley
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Low blood level of tumour suppressor miR-5193 as a target of immunotherapy to PD-L1 in gastric cancer
- Hajime Kamiya
- , Shuhei Komatsu
- & Eigo Otsuji
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| Open AccessCancer predisposition signaling in Beckwith-Wiedemann Syndrome drives Wilms tumor development
- Snehal Nirgude
- , Natali S. Sobel Naveh
- & Jennifer M. Kalish
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Enhanced antitumour response of gold nanostar-mediated photothermal therapy in combination with immunotherapy in a mouse model of colon carcinoma
- Hsin-Hua Hsieh
- , Chuan-Lin Chen
- & Chun-Yi Wu
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| Open AccessNCI10066: a Phase 1/2 study of olaparib in combination with ramucirumab in previously treated metastatic gastric and gastroesophageal junction adenocarcinoma
- Michael Cecchini
- , James M. Cleary
- & Jill Lacy
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