Focus
Focus on translating the microbiome
- Focus issue:
- April 2013 Volume 31, No 4
Researchers have generated more than 3.5 terabytes of human microbiome genomic information - more than 1,000 times that generated by the Human Genome Project. This Focus highlights progress in microbiome research and how these data might translate into a better understanding of human diseases and rational design of new therapies.
Editorial
Focus on translating the microbiome
Laying better plans for mice - p263
doi:10.1038/nbt.2560
Genetically defined germ-free animal models colonized with defined microbiota are crucial for progress in microbiome research.
Abstract - | Full Text - Laying better plans for mice | PDF - Laying better plans for mice
News
Data Page
Focus on translating the microbiome
Trends in microbiome research - p277
Susan Jones
doi:10.1038/nbt.2546
Full Text - Trends in microbiome research | PDF - Trends in microbiome research
News Features
Focus on translating the microbiome
The startup bugs - pp279 - 281
Charles Schmidt
doi:10.1038/nbt.2544
Burgeoning research on the human microbiome is facilitating the development of more mechanistically driven probiotics. Charles Schmidt investigates a smattering of probiotic- and microbiota-modifying therapeutic opportunities arising from commercial efforts.
Abstract - | Full Text - The startup bugs | PDF - The startup bugs
Focus on translating the microbiome
A snapshot of the microbiome field - pp282 - 283
Susan Jones
doi:10.1038/nbt.2545
A survey of leading scientists from academia and industry highlights notable papers that have garnered momentum in microbiome research.
Abstract - | Full Text - A snapshot of the microbiome field | PDF - A snapshot of the microbiome field
Features
Focus on translating the microbiome
Translating the human microbiome - pp304 - 308
James Brown, Willem M de Vos, Peter S DiStefano, Joël Doré, Curtis Huttenhower, Rob Knight, Trevor D Lawley, Jeroen Raes & Peter Turnbaugh
doi:10.1038/nbt.2543
Nine experts discuss the challenges in translating current research on the human microbiome into strategies for disease prediction, diagnosis and therapy.
Abstract - | Full Text - Translating the human microbiome | PDF - Translating the human microbiome
Focus on translating the microbiome
Medicines from microbiota - pp309 - 315
Bernat Olle
doi:10.1038/nbt.2548
Five years after the launch of the Human Microbiome Project, several ventures are seeking to capitalize on the clinical promise of microbiome modulation. Commercialization of drugs that influence the human flora poses some unique scientific, translational and regulatory challenges.
Abstract - | Full Text - Medicines from microbiota | PDF - Medicines from microbiota
Patents
Focus on translating the microbiome
Recent patent applications in bacteriotherapy - p318
doi:10.1038/nbt.2559
Full Text - Recent patent applications in bacteriotherapy | PDF - Recent patent applications in bacteriotherapy