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doi:10.1038/ncomms14948

Welcome to Nature Communications

Nature Communications is an open access journal that publishes high-quality research in biology, physics, chemistry, Earth sciences, and all related areas.

Browse Articles

  • Article | | open

    Osteosarcoma is a primary malignancy of bone that affects children and adults. Here, the authors sequence childhood and adult osteosarcomas, identifying mutations in insulin-like growth factor signalling genes and distinct genomic rearrangement profiles characterized by chromothripsis-amplification.

    • Sam Behjati
    • , Patrick S. Tarpey
    • , Kerstin Haase
    • , Hongtao Ye
    • , Matthew D. Young
    • , Ludmil B. Alexandrov
    • , Sarah J. Farndon
    • , Grace Collord
    • , David C. Wedge
    • , Inigo Martincorena
    • , Susanna L. Cooke
    • , Helen Davies
    • , William Mifsud
    • , Mathias Lidgren
    • , Sancha Martin
    • , Calli Latimer
    • , Mark Maddison
    • , Adam P. Butler
    • , Jon W. Teague
    • , Nischalan Pillay
    • , Adam Shlien
    • , Ultan McDermott
    • , P. Andrew Futreal
    • , Daniel Baumhoer
    • , Olga Zaikova
    • , Bodil Bjerkehagen
    • , Ola Myklebost
    • , M. Fernanda Amary
    • , Roberto Tirabosco
    • , Peter Van Loo
    • , Michael R. Stratton
    • , Adrienne M. Flanagan
    •  & Peter J. Campbell
  • Article | | open

    Robust implementations of semiconducting qubits require overcoming the effects of charge noise, which limits coherence times. Here the authors propose a decoherence-free subspace for charge qubits to protect them from uniform electric field fluctuations, proposing an implementation in a triple quantum dot.

    • Mark Friesen
    • , Joydip Ghosh
    • , M. A. Eriksson
    •  & S. N. Coppersmith
  • Article | | open

    Holes in endothelial barriers, called transendothelial cell macroapertures (TEMs), are predicted to be limited by line tension of unknown origin. Here the authors identify an actomyosin cable encircling TEMs and establish a role for ezrin in stabilising F-actin bundles, allowing their crosslinking by non-muscle myosin IIa.

    • Caroline Stefani
    • , David Gonzalez-Rodriguez
    • , Yosuke Senju
    • , Anne Doye
    • , Nadia Efimova
    • , Sébastien Janel
    • , Justine Lipuma
    • , Meng Chen Tsai
    • , Daniel Hamaoui
    • , Madhavi P. Maddugoda
    • , Olivier Cochet-Escartin
    • , Coline Prévost
    • , Frank Lafont
    • , Tatyana Svitkina
    • , Pekka Lappalainen
    • , Patricia Bassereau
    •  & Emmanuel Lemichez
  • Article | | open

    Stroke recovery requires circuit reorganization and therapeutic efforts have focused on rewiring cortical circuits after stroke, but what about thalamic inputs? Here, the authors examine how thalamocortical axons are affected by stroke and use optogenetic stimulation to promote recovery.

    • Kelly A. Tennant
    • , Stephanie L. Taylor
    • , Emily R. White
    •  & Craig E. Brown
  • Article | | open

    Electric field control of magnetization is usually weak and this hampers its application for the ultralow-power-consumption spintronic devices. Here, the authors demonstrate a mechanism to enhance the control of magnetic anisotropy by voltage-induced electric quadrupole in a metal–dielectric interface.

    • Shinji Miwa
    • , Motohiro Suzuki
    • , Masahito Tsujikawa
    • , Kensho Matsuda
    • , Takayuki Nozaki
    • , Kazuhito Tanaka
    • , Takuya Tsukahara
    • , Kohei Nawaoka
    • , Minori Goto
    • , Yoshinori Kotani
    • , Tadakatsu Ohkubo
    • , Frédéric Bonell
    • , Eiiti Tamura
    • , Kazuhiro Hono
    • , Tetsuya Nakamura
    • , Masafumi Shirai
    • , Shinji Yuasa
    •  & Yoshishige Suzuki

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