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Nature Insight Neuropsychiatric disease

This Insight highlights recent progress made in our understanding of the molecular and cellular biology, genetics, and neural circuitry underlying neuropsychiatric diseases. Together, this research points to promising integrative approaches for tackling neuropsychiatric research in the post-genomic era, and strategies for developing future therapies.

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Nature		Specificity of sensory–motor connections encoded by Sema3e–Plxnd1 recognition
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Nature Medicine		Myelin-specific T cells also recognize neuronal autoantigen in a transgenic mouse model of multiple sclerosis
Nature Cell Biology		A functional screen implicates microRNA-138-dependent regulation of the depalmitoylation enzyme APT1 in dendritic spine morphogenesis
Nature Genetics		Kif1b is essential for mRNA localization in oligodendrocytes and development of myelinated axons
Nature Reviews Neuroscience		Principles of neural ensemble physiology underlying the operation of brain–machine interfaces
Molecular Psychiatry		Rare structural variants found in attention-deficit hyperactivity disorder are preferentially associated with neurodevelopmental genes
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Molecular Systems Biology		Translational switch for long-term maintenance of synaptic plasticity
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