Focus
Focus on the Ubiquitin-Proteasome System
The ubiquitin-proteasome system controls many cellular processes either by proteolytic or non-proteolytic means. The August 2005 issue of Nature Cell Biology presents a series of specially commissioned Reviews and Perspectives highlighting new insights into this pathway.
The Focus is sponsored by Millennium Pharmaceuticals and Boston Biochem.
Editorial
Focus on the Ubiquitin-Proteasome System
Focusing on the ubiquitin-proteasome system - p725
doi:10.1038/ncb0805-725
Full Text - Developing disease | PDF (108 KB) - Focusing on the ubiquitin-proteasome system
Perspectives
Focus on the Ubiquitin-Proteasome System
Proteolysis: anytime, any place, anywhere? - pp731 - 735
Jonathon Pines & Catherine Lindon
doi:10.1038/ncb0805-731
Full Text - Proteolysis: anytime, any place, anywhere? | PDF (238 KB) - Proteolysis: anytime, any place, anywhere?
Focus on the Ubiquitin-Proteasome System
Protein quality control: chaperones culling corrupt conformations - pp736 - 741
Amie J. McClellan, Stephen Tam, Daniel Kaganovich & Judith Frydman
doi:10.1038/ncb0805-736
Full Text - Protein quality control: chaperones culling corrupt conformations | PDF (350 KB) - Protein quality control: chaperones culling corrupt conformations
Reviews
Focus on the Ubiquitin-Proteasome System
Delivery of ubiquitinated substrates to protein-unfolding machines - pp742 - 748
Suzanne Elsasser & Daniel Finley
doi:10.1038/ncb0805-742
Full Text - Delivery of ubiquitinated substrates to protein-unfolding machines | PDF (350KB) - Delivery of ubiquitinated substrates to protein-unfolding machines | - Delivery of ubiquitinated substrates to protein-unfolding machines
Focus on the Ubiquitin-Proteasome System
Weighing in on ubiquitin: the expanding role of mass-spectrometry-based proteomics - pp750 - 757
Donald S. Kirkpatrick, Carilee Denison & Steven P. Gygi
doi:10.1038/ncb0805-750
Full Text - Weighing in on ubiquitin: the expanding role of mass-spectrometry-based proteomics | PDF (304 KB) - Weighing in on ubiquitin: the expanding role of mass-spectrometry-based proteomics
Focus on the Ubiquitin-Proteasome System
Ubiquitin signalling in the NF-κB pathway - pp758 - 765
JZhijian J. Chen
doi:10.1038/ncb0805-758
Full Text - Ubiquitin signalling in the NF-κB pathway | PDF (480 KB) - Ubiquitin signalling in the NF-κB pathway | - Ubiquitin signalling in the NF-κB pathway
Focus on the Ubiquitin-Proteasome System
ERAD: the long road to destruction - pp766 - 772
Birgit Meusser, Christian Hirsch, Ernst Jarosch & Thomas Sommer
doi:10.1038/ncb0805-766
Abstract - ERAD: the long road to destruction | Full Text - ERAD: the long road to destruction | PDF (376 KB) - ERAD: the long road to destruction