The Nature Publishing Group (NPG) has published many landmark papers on the ubiquitin-proteasome system. The NPG Library contains a select group of recent papers on this topic that have been published in Nature Research and Review Journals. Clicking on any of these links will take you to the online articles.
Articles & Letters
S-nitrosylated GAPDH initiates apoptotic cell death by nuclear translocation following Siah1 binding Makoto R. Hara, Nishant Agrawal, Sangwon F. Kim, Matthew B. Cascio, Masahiro Fujimuro, Yuji Ozeki, Masaaki Takahashi, Jaime H. Cheah, Stephanie K. Tankou, Lynda D. Hester, Christopher D. Ferris, S. Diane Hayward, Solomon H. Snyder & Akira Sawa Nature Cell Biology 7, 665–674 (2005) Abstract|Full Text|PDF
Insights into E3 ligase activity revealed by a SUMO-RanGAP1-Ubc9-Nup358 complex David Reverter & Christopher D. Lima Nature 435, 687–692 (2 June 2005) Abstract|Full Text|PDF |
Supplementary Information
SUMO-modified PCNA recruits Srs2 to prevent recombination during S phase Boris Pfander, George-Lucian Moldovan, Meik Sacher, Carsten Hoege & Stefan Jentsch Nature 436, 428–433 (1 June 2005) Abstract|Full Text|PDF |
Supplementary Information
The Arabidopsis F-box protein TIR1 is an auxin receptor Stefan Kepinski & Ottoline Leyser Nature 435, 446–451 (26 May 2005) Abstract|Full Text|PDF
Activity probe for in vivo profiling of the specificity of proteasome inhibitor bortezomib Celia R Berkers, Martijn Verdoes, Eben Lichtman, Edda Fiebiger, Benedikt M Kessler, Kenneth C Anderson, Hidde L Ploegh, Huib Ovaa & Paul J Galardy Nature Methods 2, 357–362 (2005) Abstract|Full Text|PDF |
Supplementary Information
CSN facilitates Cullin-RING ubiquitin ligase function by counteracting autocatalytic adapter instability Susan Wee, Rory K. Geyer, Takashi Toda & Dieter A. Wolf Nature Cell Biology 7, 387–391 (2005) Abstract|Full Text|PDF |
Supplementary Information
SUMO modification of the ubiquitin-conjugating enzyme E2-25K Andrea Pichler, Puck Knipscheer, Edith Oberhofer, Willem J van Dijk, Roman Körner, Jesper Velgaard Olsen, Stefan Jentsch, Frauke Melchior & Titia K Sixma Nature Structural & Molecular Biology 12, 264–269 (2005) Abstract|Full Text|PDF |
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Real-time monitoring of ubiquitination in living cells by BRET Julie Perroy, Stephanie Pontier, Pascale G Charest, Muriel Aubry & Michel Bouvier Nature Methods 1, 203–208 (2004) Abstract|Full Text|PDF |
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Role of ISG15 protease UBP43 (USP18) in innate immunity to viral infection Kenneth J Ritchie, Chang S Hahn, Keun Il Kim, Ming Yan, Dabralee Rosario, Li Li, Juan Carlos de la Torre & Dong-Er Zhang Nature Medicine 10, 1374–1378 (2004) Abstract|Full Text|PDF
Role of histone H2A ubiquitination in Polycomb silencing Hengbin Wang, Liangjun Wang, Hediye Erdjument-Bromage, Miguel Vidal, Paul Tempst, Richard S. Jones & Yi Zhang Nature 431, 873–878 (14 October 2004) Abstract|Full Text|PDF
Targeted ubiquitination of CDT1 by the DDB1-CUL4A-ROC1 ligase in response to DNA damage Jian Hu, Chad M. McCall, Tomohiko Ohta & Yue Xiong Nature Cell Biology 6, 1003–1009 (2004) Abstract|Full Text|PDF |
Supplementary Information
A unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8 Danny T Huang, David W Miller, Rose Mathew, Robert Cassell, James M Holton, Martine F Roussel & Brenda A Schulman Nature Structural & Molecular Biology 11, 927–935 (2004) Abstract|Full Text|PDF |
Supplementary Information
The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses David L Boone, Emre E Turer, Eric G Lee, Regina-Celeste Ahmad, Matthew T Wheeler, Colleen Tsui, Paula Hurley, Marcia Chien, Sophia Chai, Osamu Hitotsumatsu, Elizabeth McNally, Cecile Pickart & Averil Ma Nature Immunology 5, 1052–1060 (2004) Abstract|Full Text|PDF
The anaphase promoting complex/cyclosome is recruited to centromeres by the spindle assembly checkpoint Claire Acquaviva, Franz Herzog, Claudine Kraft & Jonathon Pines Nature Cell Biology 6, 892–898 (2004) Abstract|Full Text|PDF |
Supplementary Information
Apollon ubiquitinates SMAC and caspase-9, and has an essential cytoprotection function Yanyan Hao, Keiko Sekine, Atsushi Kawabata, Hitoshi Nakamura, Toshiyasu Ishioka, Hirokazu Ohata, Ryohei Katayama, Chizuko Hashimoto, Xiaodong Zhang, Tetsuo Noda, Takashi Tsuruo & Mikihiko Naito Nature Cell Biology 6, 849–860 (2004) Abstract|Full Text|PDF |
De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-B signalling Ingrid E. Wertz, Karen M. O'Rourke, Honglin Zhou, Michael Eby, L. Aravind, Somasekar Seshagiri, Ping Wu, Christian Wiesmann, Rohan Baker, David L. Boone, Averil Ma, Eugene V. Koonin and Vishva M. Dixit Nature 430, 694–699 (5 August 2004) Abstract|Full Text|PDF |
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A membrane protein required for dislocation of misfolded proteins from the ER Brendan N. Lilley & Hidde L. Ploegh Nature 429, 834–840 (24 June 2004) Abstract|Full Text|PDF |
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A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol Yihong Ye, Yoko Shibata, Chi Yun, David Ron & Tom A. Rapoport Nature 429, 841–847 (24 June 2004) Abstract|Full Text|PDF |
Supplementary Information
Proteolysis-independent regulation of the transcription factor Met4 by a single Lys 48-linked ubiquitin chain Yihong Ye, Yoko Shibata, Chi Yun, David Ron & Tom A. Rapoport Nature Cell Biology 6, 634–641 (2004) Abstract|Full Text|PDF |
Supplementary Information
Reviews, Perspectives & Commentaries
Ubiquitin and ubiquitin-like proteins as multifunctional signals Rebecca L. Welchman, Colin Gordon & R. John Mayer Nature Reviews Molecular Cell Biology6, 599–609 (2005) Abstract|Full Text|PDF
Ubiquitin-binding domains Linda Hicke, Heidi L. Schubert & Christopher P Hill Nature Reviews Molecular Cell Biology6, 610–621 (2005) Abstract|Full Text|PDF
Function and regulation of cullin–ring ubiquitin ligases Matthew D. Petroski & Raymond J. Deshaies Nature Reviews Molecular Cell Biology 6, 9–20 (2005) Abstract|Full Text|PDF |
Supplementary Information
E3 ubiquitin ligases as T cell anergy factors Daniel L Mueller Nature Immunology 5, 883–890 (2004) Abstract|Full Text|PDF
The proteasome: a suitable antineoplastic target Julian Adams Nature Reviews Cancer 4, 349–360 (2004) Abstract|Full Text|PDF
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