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The ubiquitin-proteasome system controls many cellular processes either by proteolytic or non-proteolytic means. The August 2005 issue of Nature Cell Biology presents a series of specially commissioned Reviews and Perspectives highlighting new insights into this pathway. The Focus is sponsored by Millennium Pharmaceuticals and Boston Biochem. |
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| Editorial | Top |  |  |  | Focus on the Ubiquitin-Proteasome System Focusing on the ubiquitin−proteasome system p725 doi:10.1038/ncb0805-725 Full text | PDF
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|  | | Perspectives | Top |  |  |  | Focus on the Ubiquitin-Proteasome System Proteolysis: anytime, any place, anywhere? pp731 - 735 Jonathon Pines
& Catherine Lindon doi:10.1038/ncb0805-731 Abstract | Full text | PDF
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|  |  |  | Focus on the Ubiquitin-Proteasome System Protein quality control: chaperones culling corrupt conformations pp736 - 741 Amie J. McClellan, Stephen Tam, Daniel Kaganovich
& Judith Frydman doi:10.1038/ncb0805-736 Abstract | Full text | PDF
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|  | | Reviews | Top |  |  |  | Focus on the Ubiquitin-Proteasome System Delivery of ubiquitinated substrates to protein-unfolding machines pp742 - 749 Suzanne Elsasser
& Daniel Finley doi:10.1038/ncb0805-742 Abstract | Full text | PDF
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| Supplementary Information |  |  |  | Focus on the Ubiquitin-Proteasome System Weighing in on ubiquitin: the expanding role of mass-spectrometry-based proteomics pp750 - 757 Donald S. Kirkpatrick, Carilee Denison
& Steven P. Gygi doi:10.1038/ncb0805-750 Abstract | Full text | PDF
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|  |  |  | Focus on the Ubiquitin-Proteasome System Ubiquitin signalling in the NF- B pathway pp758 - 765 Zhijian J. Chen doi:10.1038/ncb0805-758 Abstract | Full text | PDF (480K) | Supplementary Information |  |  |  | Focus on the Ubiquitin-Proteasome System ERAD: the long road to destruction pp766 - 772 Birgit Meusser, Christian Hirsch, Ernst Jarosch
& Thomas Sommer doi:10.1038/ncb0805-766 Abstract | Full text | PDF
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