Microscopy articles within Nature Communications

Featured

  • Article |

    In microscopy, the standard quantum limit represents the best achievable signal-to-noise ratio for a given light intensity. Here, the authors build an optical microscope that uses entanglement between photon pairs to overcome this barrier.

    • Takafumi Ono
    • , Ryo Okamoto
    •  & Shigeki Takeuchi
  • Article |

    Imaging cells within live animals is important in biomedical research, but this process is limited by the availability of probes. Ritsma et al.combine intravital microscopy with immunohistochemistry to increase the panel of available reagents and examine the role of T cells in the migration of breast cancer cells.

    • Laila Ritsma
    • , Nienke Vrisekoop
    •  & Jacco van Rheenen
  • Article
    | Open Access

    Systematic large-scale analysis of embryonic development requires the processing of large amounts of microscopy data. Here Schmid et al.solve this problem by developing a high-speed imaging system that projects zebrafish embryos onto a ‘world map’ in real time, revealing characteristic migration patterns in the early endoderm.

    • Benjamin Schmid
    • , Gopi Shah
    •  & Jan Huisken
  • Article |

    In vitro, retroviruses spread between cells via structures resembling synapses. Sewaldet al. now demonstrate that virological synapses can also be observed in living mice by intravital microscopy, validating this concept in vivo.

    • Xaver Sewald
    • , David G. Gonzalez
    •  & Walther Mothes
  • Article |

    The degree of polydispersity of colloidal suspensions is known to have consequences for their physical properties. Kuritaet al. present a general method for determining the sizes of individual particles, and thus the polydispersity, using only the coordinates of the centre positions of spherical particles.

    • Rei Kurita
    • , David B. Ruffner
    •  & Eric R. Weeks
  • Article |

    Calcium-sensing fluorescent proteins such as TN-XXL are valuable tools for studying cellular function but, when expressed in mice, may affect animal physiology and behaviour. The authors of this paper create transgenic mice expressing TN-XXL and show that long-term expression of TN-XXL is tolerated well.

    • Stephan Direnberger
    • , Marsilius Mues
    •  & Oliver Griesbeck
  • Article
    | Open Access

    Fibre-based technologies provide miniaturization, flexibility and the capability to access hard to reach areas. Čižmár and Dholakia exploit disorder in multimode fibres to enable a variety of imaging modalities, including bright- and dark-field microscopy and fluorescent imaging, using a single waveguide.

    • Tomáš Čižmár
    •  & Kishan Dholakia
  • Article |

    Strategies to tune the surface properties of topological insulators are essential, if they are to find use in applications. Using a combination of theoretical and experimental techniques, this study examines how the properties of ordered ternary topological insulators vary with the content of group IV elements.

    • Sergey V. Eremeev
    • , Gabriel Landolt
    •  & Evgueni V. Chulkov
  • Article
    | Open Access

    The influenza A virus genome consists of eight RNA segments, which permits genetic reassortment and contributes to the emergence of novel strains with pandemic potential. Here, electron tomography is used to study the three-dimensional structure of ribonucleoprotein complexes within progeny virions.

    • Takeshi Noda
    • , Yukihiko Sugita
    •  & Yoshihiro Kawaoka
  • Article |

    Ferroelectric materials are characterized by a spontaneous polarization, which in practical applications is manipulated by an electric field. This study examines how defects affect the switching with atomic resolution, by usingin situaberration-corrected transmission electron microscopy.

    • Peng Gao
    • , Christopher T. Nelson
    •  & Xiaoqing Pan
  • Article |

    X-ray ptychography has been used to extend the field of view in high-resolution quantitative imaging. Godardet al. develop Bragg-mode ptychography to reconstruct, in three dimensions, a crystalline specimen that is too large to be studied as a single object with a coherence-limited X-ray beam.

    • P. Godard
    • , G. Carbone
    •  & V. Chamard
  • Article
    | Open Access

    Being able to determine the wetting properties of individual nanoparticles would aid the preparation of particles with controlled surface properties. Isaet al. develop an in situ freeze-fracture shadow-casting method and use this to determine structural and thermodynamic properties of various 10 nm particles at fluid interfaces.

    • Lucio Isa
    • , Falk Lucas
    •  & Erik Reimhult
  • Article
    | Open Access

    Flux-closure patterns are rarely observed in ferroelectric materials and almost exclusively form at the nanoscale. McQuaidet al. report mesoscopic dipole closure patterns formed in free-standing single-crystal lamellae of BaTiO3, thought to result from an unusual set of experimental conditions.

    • R.G.P. McQuaid
    • , L.J. McGilly
    •  & J.M. Gregg
  • Article |

    The unoccupied electronic levels of graphene are modified by corrugation, doping and presence of impurities. Here, the authors map discrete electronic domains within a single graphene sheet using scanning transmission X-ray microscopy and provide insight into the modification of unoccupied levels.

    • Brian J. Schultz
    • , Christopher J. Patridge
    •  & Sarbajit Banerjee
  • Article
    | Open Access

    Nanoparticles continue to find research and industrial applications, but no single technique exists to characterise their physical properties. Now, an analytical ultracentrifugation method is described which allows the simulataneous determination of nanoparticle size, density and molecular weight distribution.

    • Randy P. Carney
    • , Jin Young Kim
    •  & Osman M. Bakr
  • Article |

    Metal-based nanostructures offer a solution to scale down photonics to the nanoscale. Sorgeret al. directly demonstrate waveguiding of ultra-small propagating waves at visible and near-infrared frequencies using NSOM imaging, with the potential for nanoscale photonic applications such as bio-sensing.

    • Volker J. Sorger
    • , Ziliang Ye
    •  & Xiang Zhang
  • Article |

    Solid gold is most stable as a face-centred cubic structure, and stable colloidal gold with hexagonal close packing has not been produced. Huanget al.prepare square gold sheets with hexagonal close packing that are stable under ambient conditions.

    • Xiao Huang
    • , Shaozhou Li
    •  & Hua Zhang