Short Communication
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Open Access
Featured
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Clinical Study
| Open AccessHistopathological features of papillary thyroid carcinomas detected during four screening examinations of a Ukrainian-American cohort
- Tetiana I Bogdanova
- , Liudmyla Yu Zurnadzhy
- & Alina V Brenner
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Genetics and Genomics
| Open AccessHypermethylation of genes in testicular embryonal carcinomas
- Hoi-Hung Cheung
- , Yanzhou Yang
- & Wai-Yee Chan
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Clinical Study
| Open AccessClinico-pathological nomogram for predicting BRAF mutational status of metastatic colorectal cancer
- Fotios Loupakis
- , Roberto Moretto
- & Emilio Bria
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Genetics and Genomics
| Open AccessOverexpression of major CDKN3 transcripts is associated with poor survival in lung adenocarcinoma
- Chao Fan
- , Lu Chen
- & Jie Wu
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Mini Review
| Open AccessBig Data: the challenge for small research groups in the era of cancer genomics
- Aisyah Mohd Noor
- , Lars Holmberg
- & Anita Grigoriadis
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Molecular Diagnostics
| Open AccessPTEN loss in circulating tumour cells correlates with PTEN loss in fresh tumour tissue from castration-resistant prostate cancer patients
- Elizabeth A Punnoose
- , Roberta Ferraldeschi
- & Johann de Bono
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Letter to the Editor
| Open AccessComment on: ‘KRAS and BRAF mutations are prognostic biomarkers in patients undergoing lung metastasectomy of colorectal cancer.’ Variation in survival associated with proto-oncongenes is not evidence for effectiveness of lung metastasectomy
- Giuseppe Cardillo
- , Sahar Mokhles
- & Tom Treasure
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Letter to the Editor
| Open AccessReply: Comment on ‘KRAS and BRAF mutations are prognostic biomarkers in patients undergoing lung metastasectomy of colo-rectal cancer’
- Stéphane Renaud
- , Pierre-Emmanuel Falcoz
- & Gilbert Massard
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Letter to the Editor
| Open AccessReply: Comment on ‘Meta-analysis of BRAF mutation as a predictive biomarker of benefit from anti-EGFR monoclonal-antibody therapy for RAS wild-type metastatic colorectal cancer’
- Andrew Rowland
- , Mafalda M Dias
- & Michael J Sorich
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Letter to the Editor
| Open AccessBRAF-mutated metastatic colorectal cancer between past and future
- Chiara Cremolini
- , Massimo Di Maio
- & Filippo Pietrantonio
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Genetics and Genomics
| Open AccessTERT promoter mutations are frequent and show association with MED12 mutations in phyllodes tumors of the breast
- Masayuki Yoshida
- , Reiko Ogawa
- & Shigeki Sekine
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Translational Therapeutics
| Open AccessPIK3CA oncogenic mutations represent a major mechanism of resistance to trastuzumab in HER2/neu overexpressing uterine serous carcinomas
- Jonathan D Black
- , Salvatore Lopez
- & Alessandro D Santin
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Molecular Diagnostics
| Open AccessKRAS, NRAS, BRAF mutation comparison of endoscopic and surgically removed primary CRC paired samples: is endoscopy biopsy material adequate for molecular evaluation?
- Z Saridaki
- , X Saegart
- & S Tejpar
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Genetics and Genomics
| Open AccessTarget gene mutational pattern in Lynch syndrome colorectal carcinomas according to tumour location and germline mutation
- Manuela Pinheiro
- , Carla Pinto
- & Manuel R Teixeira
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Molecular Diagnostics
| Open AccessIdentification of a hypoxia-regulated miRNA signature in bladder cancer and a role for miR-145 in hypoxia-dependent apoptosis
- C Blick
- , A Ramachandran
- & A L Harris
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Translational Therapeutics
| Open AccessGene therapy with SOCS1 for gastric cancer induces G2/M arrest and has an antitumour effect on peritoneal carcinomatosis
- Rie Natatsuka
- , Tsuyoshi Takahashi
- & Tetsuji Naka
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Translational Therapeutics
| Open AccessBRCA1 and BRCA2 mutations sensitize to chemotherapy in patient-derived pancreatic cancer xenografts
- I Lohse
- , A Borgida
- & D W Hedley
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Molecular Diagnostics
| Open AccessSerum GADD45a methylation is a useful biomarker to distinguish benign vs malignant prostate disease
- I M Reis
- , K Ramachandran
- & R Singal
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Short Communication
| Open AccessImpact of KRAS codon subtypes from a randomised phase II trial of selumetinib plus docetaxel in KRAS mutant advanced non-small-cell lung cancer
- P A Jänne
- , I Smith
- & P Smith
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Molecular Diagnostics
| Open AccessThe expression of tumour suppressors and proto-oncogenes in tissues susceptible to their hereditary cancers
- Brian Muir
- & Leonard Nunney
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Epidemiology
| Open AccessAn analysis of the association between prostate cancer risk loci, PSA levels, disease aggressiveness and disease-specific mortality
- J Sullivan
- , R Kopp
- & R J Klein
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Molecular Diagnostics
| Open AccessMicrosatellite instable vs stable colon carcinomas: analysis of tumour heterogeneity, inflammation and angiogenesis
- L De Smedt
- , J Lemahieu
- & X Sagaert
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Molecular Diagnostics
| Open AccessHigh leukocyte mitochondrial DNA content contributes to poor prognosis in glioma patients through its immunosuppressive effect
- Y Chen
- , J Zhang
- & J Xing
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Molecular Diagnostics
| Open AccessPTEN loss is associated with follicular variant of Middle Eastern papillary thyroid carcinoma
- S Beg
- , A K Siraj
- & K S Al-Kuraya
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Genetics and Genomics
| Open AccessNGS-based approach to determine the presence of HPV and their sites of integration in human cancer genome
- P Chandrani
- , V Kulkarni
- & A Dutt
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Genetics and Genomics
| Open AccessCombination of microsatellite instability and BRAF mutation status for subtyping colorectal cancer
- T T Seppälä
- , J P Böhm
- & J-P Mecklin
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Full Paper
| Open AccessRevisiting the transcriptional analysis of primary tumours and associated nodal metastases with enhanced biological and statistical controls: application to thyroid cancer
- M Tarabichi
- , M Saiselet
- & V Detours
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Translational Therapeutics
| Open AccessMicroRNA-224 is associated with colorectal cancer progression and response to 5-fluorouracil-based chemotherapy by KRAS-dependent and -independent mechanisms
- E B Amankwatia
- , P Chakravarty
- & G Smith
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Short Communication
| Open AccessDroplet digital PCR measurement of HER2 in patients with gastric cancer
- H Kinugasa
- , K Nouso
- & K Yamamoto
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Full Paper
| Open AccessCirculating cell-free AR and CYP17A1 copy number variations may associate with outcome of metastatic castration-resistant prostate cancer patients treated with abiraterone
- S Salvi
- , V Casadio
- & U De Giorgi
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Genetics and Genomics
| Open AccessActivating GNAS and KRAS mutations in gastric foveolar metaplasia, gastric heterotopia, and adenocarcinoma of the duodenum
- A Matsubara
- , R Ogawa
- & S Sekine
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Genetics and Genomics
| Open AccessAssessing the clinical value of targeted massively parallel sequencing in a longitudinal, prospective population-based study of cancer patients
- S Q Wong
- , A Fellowes
- & S B Fox
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Genetics and Genomics
| Open AccessTruncating mutations of PPM1D are found in blood DNA samples of lung cancer patients
- A Zajkowicz
- , D Butkiewicz
- & M Rusin
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Genetics and Genomics
| Open AccessMitochondrial dysfunction and risk of cancer
- M Lund
- , M Melbye
- & J Vissing
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Molecular Diagnostics
| Open AccessKRAS and BRAF mutations are prognostic biomarkers in patients undergoing lung metastasectomy of colorectal cancer
- S Renaud
- , B Romain
- & G Massard
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Genetics and Genomics
| Open AccessA high incidence of WT1 abnormality in bilateral Wilms tumours in Japan, and the penetrance rates in children with WT1 germline mutation
- Y Kaneko
- , H Okita
- & M Fukuzawa
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Genetics and Genomics
| Open AccessLow-level constitutional mosaicism of a de novoBRCA1 gene mutation
- E Friedman
- , N Efrat
- & S Topper
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Translational Therapeutics
| Open AccessBRCA1 haplotype and clinical benefit of trabectedin in soft-tissue sarcoma patients
- A Laroche-Clary
- , V Chaire
- & A Italiano
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Short Communication
| Open AccessAssociation between KRAS mutation and lung metastasis in advanced colorectal cancer
- A A L Pereira
- , J F M Rego
- & S Kopetz
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Genetics and Genomics
| Open AccessMutational profiling of familial male breast cancers reveals similarities with luminal A female breast cancer with rare TP53 mutations
- S Deb
- , S Q Wong
- & S B Fox
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Genetics and Genomics
| Open AccessMicroRNA expression profiling in male and female familial breast cancer
- R Pinto
- , S De Summa
- & S Tommasi
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Clinical Study
| Open AccessInfluence of segmental chromosome abnormalities on survival in children over the age of 12 months with unresectable localised peripheral neuroblastic tumours without MYCN amplification
- R Defferrari
- , K Mazzocco
- & G P Tonini
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Letter to the Editor
| Open AccessReply to ‘Comment on: The NQO1 polymorphism C609T (Pro187Ser) and cancer susceptibility: a comprehensive meta-analysis’
- B Lajin
- & A Alachkar
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Letter to the Editor
| Open AccessNeed for clarification of data in a recent meta-analysis on the association of NQO1 C609T polymorphism with cancer risk
- X Cao
- & W Shen
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Mini Review
| Open AccessTranslation of genomics-guided RNA-based personalised cancer vaccines: towards the bedside
- V Boisguérin
- , J C Castle
- & U Sahin
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Genetics and Genomics
| Open AccessTERT promoter mutations in gliomas, genetic associations and clinico-pathological correlations
- M Labussière
- , A L Di Stefano
- & M Sanson
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Genetics and Genomics
| Open AccessGenotranscriptomic meta-analysis of the Polycomb gene CBX2 in human cancers: initial evidence of an oncogenic role
- P-L Clermont
- , L Sun
- & C D Helgason
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Molecular Diagnostics
| Open AccessKRAS mutational subtype and copy number predict in vitro response of human pancreatic cancer cell lines to MEK inhibition
- H Hamidi
- , M Lu
- & R S Finn
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