Featured
-
-
Article
| Open AccessSelective inhibition of HDAC6 promotes bladder cancer radiosensitization and mitigates the radiation-induced CXCL1 signalling
- Yu-Chieh Tsai
- , Tzu-Yin Wang
- & Sheng-Fang Su
-
Article
| Open AccessDisentangling the aetiological pathways between body mass index and site-specific cancer risk using tissue-partitioned Mendelian randomisation
- Genevieve M. Leyden
- , Michael P. Greenwood
- & Tom G. Richardson
-
Article |
Tandem histone methyltransferase upregulation defines a unique aggressive prostate cancer phenotype
- Mikolaj Filon
- , Joseph Gawdzik
- & David Jarrard
-
Article
| Open AccessA 10-gene prognostic signature points to LIMCH1 and HLA-DQB1 as important players in aggressive cervical cancer disease
- Mari K. Halle
- , Marte Sødal
- & Camilla Krakstad
-
Article
| Open AccessHepatic metastasis of gastric cancer is associated with enhanced expression of ethanolamine kinase 2 via the p53–Bcl-2 intrinsic apoptosis pathway
- Takashi Miwa
- , Mitsuro Kanda
- & Yasuhiro Kodera
-
Article
| Open AccessReversal of glucocorticoid resistance in paediatric acute lymphoblastic leukaemia is dependent on restoring BIM expression
- Cara E. Toscan
- , Duohui Jing
- & Richard B. Lock
-
Article
| Open AccessA common polymorphism in the retinoic acid pathway modifies adrenocortical carcinoma age-dependent incidence
- Mirvat Surakhy
- , Marsha Wallace
- & Gareth L. Bond
-
Article
| Open AccessEarly immune modulation by single-agent trastuzumab as a marker of trastuzumab benefit
- Tiziana Triulzi
- , Viola Regondi
- & Elda Tagliabue
-
Article
| Open AccessWT1 expression in vessels varies with histopathological grade in tumour-bearing and control tissue from patients with breast cancer
- Richard J. McGregor
- , You-Ying Chau
- & Patrick W. F. Hadoke
-
Article
| Open AccessColon-specific eQTL analysis to inform on functional SNPs
- Victor Moreno
- , M. Henar Alonso
- & Xavier Solé
-
Genetics and Genomics
| Open AccessGlobal metabolomic profiling of uterine leiomyomas
- Hanna-Riikka Heinonen
- , Miika Mehine
- & Eevi Kaasinen
-
Short Communication
| Open AccessAssociation between hypoxic volume and underlying hypoxia-induced gene expression in oropharyngeal squamous cell carcinoma
- Yae-eun Suh
- , Katherine Lawler
- & Mahvash Tavassoli
-
Molecular Diagnostics
| Open AccessThe expression of tumour suppressors and proto-oncogenes in tissues susceptible to their hereditary cancers
- Brian Muir
- & Leonard Nunney
-
Molecular Diagnostics
| Open AccessCorrelation between human papillomavirus and p16 overexpression in oropharyngeal tumours: a systematic review
- C Grønhøj Larsen
- , M Gyldenløve
- & C von Buchwald
-
Molecular Diagnostics
| Open AccessCollagen type XI α1 facilitates head and neck squamous cell cancer growth and invasion
- J C Sok
- , J A Lee
- & S M Thomas
-
Molecular Diagnostics
| Open AccessExpression of nuclear survivin in normal skin and squamous cell carcinoma: a possible role in tumour invasion
- K Dallaglio
- , T Petrachi
- & C Pincelli
-
Genetics and Genomics
| Open AccessStrong reduction of AGO2 expression in melanoma and cellular consequences
- D Völler
- , J Reinders
- & A-K Bosserhoff
-
Genetics and Genomics
| Open AccessIodine-131 dose-dependent gene expression: alterations in both normal and tumour thyroid tissues of post-Chernobyl thyroid cancers
- M Abend
- , R M Pfeiffer
- & A V Brenner
-
Genetics and Genomics
| Open AccessImpaired expression of protein phosphatase 2A subunits enhances metastatic potential of human prostate cancer cells through activation of AKT pathway
- P Pandey
- , P Seshacharyulu
- & S K Batra
-
Molecular Diagnostics
| Open AccessApical MUC1 expression revealed on the foveolar epithelium in H. pylori gastritis
- M Rashid
- , A S Teixeira
- & D M Swallow
-
Molecular Diagnostics
| Open AccessBidirectional modulation of endogenous EpCAM expression to unravel its function in ovarian cancer
- B T F van der Gun
- , C Huisman
- & M G Rots
-
Molecular Diagnostics
| Open AccessTissue factor expression in the metaplasia–adenoma–carcinoma sequence of gastric cancer in a European population
- L Lo
- , H Valentine
- & Y Ang
-
Molecular Diagnostics
| Open AccessExpression of oestrogen receptor β and prognosis of colorectal cancer
- A Rudolph
- , C Toth
- & J Chang-Claude
-
Molecular Diagnostics
| Open AccessExpression and prognostic significance of Src family members in renal clear cell carcinoma
- T Qayyum
- , P A McArdle
- & J Edwards
-
Molecular Diagnostics
| Open AccessExpression of MAGE-A3, NY-ESO-1, LAGE-1 and PRAME in urothelial carcinoma
- L Dyrskjøt
- , K Zieger
- & T F Ørntoft
-
Molecular Diagnostics
| Open Accessc-Myc and EBV–LMP1: two opposing regulators of the HLA class I antigen presentation machinery in epithelial cells
- C S Tudor
- , C W Dawson
- & M Buettner
-
Translational Therapeutics
| Open AccessIntrinsic resistance to selumetinib, a selective inhibitor of MEK1/2, by cAMP-dependent protein kinase A activation in human lung and colorectal cancer cells
- T Troiani
- , L Vecchione
- & F Ciardiello
-
Molecular Diagnostics
| Open AccessDownregulation of membrane complement inhibitors CD55 and CD59 by siRNA sensitises uterine serous carcinoma overexpressing Her2/neu to complement and antibody-dependent cell cytotoxicity in vitro: implications for trastuzumab-based immunotherapy
- S Bellone
- , D Roque
- & A D Santin
-
Genetics and Genomics
| Open AccessPPARγ agonists regulate the expression of stemness and differentiation genes in brain tumour stem cells
- E Pestereva
- , S Kanakasabai
- & J J Bright
-
Molecular Diagnostics
| Open AccessExpression of Forkhead box P3 in tumour cells causes immunoregulatory function of signet ring cell carcinoma of the stomach
- M Yoshii
- , H Tanaka
- & K Hirakawa
-
Translational Therapeutics
| Open AccessThe cap-translation inhibitor 4EGI-1 induces apoptosis in multiple myeloma through Noxa induction
- G Descamps
- , P Gomez-Bougie
- & M Amiot
-
Translational Therapeutics
| Open AccessNegative argininosuccinate synthetase expression in melanoma tumours may predict clinical benefit from arginine-depleting therapy with pegylated arginine deiminase
- L G Feun
- , A Marini
- & N Savaraj
-
Molecular Diagnostics
| Open AccessExpression of sphingosine 1-phosphate receptor 4 and sphingosine kinase 1 is associated with outcome in oestrogen receptor-negative breast cancer
- J Ohotski
- , J S Long
- & J Edwards
-
Molecular Diagnostics
| Open AccessClinical significance of CD151 overexpression in subtypes of invasive breast cancer
- M J Kwon
- , S Park
- & Y-L Choi
-
Molecular Diagnostics
| Open AccessHost-derived MMP-13 exhibits a protective role in lung metastasis of melanoma cells by local endostatin production
- H Fukuda
- , S Mochizuki
- & Y Okada
-
Molecular Diagnostics
| Open AccessGSTPi-positive tumour microenvironment-associated fibroblasts are significantly associated with GSTPi-negative cancer cells in paired cases of primary invasive breast cancer and axillary lymph node metastases
- B Chaiwun
- , N Sukhamwang
- & S A Imam
-
Translational Therapeutics
| Open AccessRapid non-genomic signalling by 17β-oestradiol through c-Src involves mTOR-dependent expression of HIF-1α in breast cancer cells
- S Sudhagar
- , S Sathya
- & B S Lakshmi
-
Molecular Diagnostics
| Open AccessExpression and functional role of CRIPTO-1 in cutaneous melanoma
- A De Luca
- , L Lamura
- & N Normanno
-
Molecular Diagnostics
| Open AccessSupernatants from lymphocytes stimulated with Bacillus Calmette-Guerin can modify the antigenicity of tumours and stimulate allogeneic T-cell responses
- W M Liu
- , D W Fowler
- & A G Dalgleish
-
Molecular Diagnostics
| Open AccessCTGF is overexpressed in malignant melanoma and promotes cell invasion and migration
- S Braig
- , S Wallner
- & A-K Bosserhoff
-
Clinical Study
| Open AccessA systematic review to establish the frequency of cyclooxygenase-2 expression in normal breast epithelium, ductal carcinoma in situ, microinvasive carcinoma of the breast and invasive breast cancer
- J A Glover
- , C M Hughes
- & L J Murray
-
Molecular Diagnostics
| Open AccessInhibin/activin expression in human and rodent liver: subunits α and βB as new players in human hepatocellular carcinoma?
- K Frost
- , K Seir
- & C Rodgarkia-Dara
-
Letter to the Editor
| Open AccessReply: Choosing a stable housekeeping gene and protein is essential in generating valid gene and protein expression results
- D Revaud
- , J Caradec
- & S Loric
-
Letter to the Editor
| Open AccessChoosing a stable housekeeping gene and protein is essential in generating valid gene and protein expression results
- M Sullivan-Gunn
- , E Hinch
- & P Lewandowski
-
Molecular Diagnostics
| Open AccessExpression of NRG1 and its receptors in human bladder cancer
- J A Forster
- , A B Paul
- & M A Knowles
-
Molecular Diagnostics
| Open AccessRole of multidrug resistance protein 2 (MRP2) in chemoresistance and clinical outcome in oesophageal squamous cell carcinoma
- M Yamasaki
- , T Makino
- & Y Doki
-
Molecular Diagnostics
| Open AccessEnhancement of osteoclastogenic activity in osteolytic prostate cancer cells by physical contact with osteoblasts
- A Shiirevnyamba
- , T Takahashi
- & H Uehara
-
Molecular Diagnostics
| Open AccessCD9P-1 expression correlates with the metastatic status of lung cancer, and a truncated form of CD9P-1, GS-168AT2, inhibits in vivo tumour growth
- W Guilmain
- , S Colin
- & S Al-Mahmood
-
Molecular Diagnostics
| Open AccessCytosolic phospholipase A2-α expression in breast cancer is associated with EGFR expression and correlates with an adverse prognosis in luminal tumours
- F Caiazza
- , N S McCarthy
- & W Thomas