The power of public access: the human genome project and the scientific process. Quackenbush, J. Nature Genetics September (2001)

Knockout mice: a paradigm shift in modern immunology. Mak, T. W. et al. Nature Reviews Immunology October (2001) A Review of how advances in genetic engineering and mouse knockout technologies have generated new insights into the workings of the immune system and embryonic development.

The functional genomics experience (are you experienced?) Asnagli, H. & Murphy, K. M. Nature Immunology September (2001) A News and Views article showing how genome-wide sequence analysis promises to yield new insights in global regulatory gene control.

Genetic selection and the lure of SIN. Nolan, G. P. Nature Biotechnology September (2001) A News and Views piece on a rapid method for exploring gene function using alphavirus-based expression cloning.

The INK4a/ARF network in tumour suppression. Sherr, C. J. Nature Reviews Molecular Cell Biology October (2001)

The melanosome: membrane dynamics in black and white. Marks, M. S. & Seabra, M. C. Nature Reviews Molecular Cell Biology October (2001)

Clocks and Hox. Tabin, C. J. & Johnson, R. L. Nature 23 August (2001) A News and Views article on two studies that show a causal connection between the differential expression of Hox genes along the anterior–posterior axis and the vertebrate segmentation clock.

Cancer genetics: from Boveri and Mendel to microarrays. Balmain, A. Nature Reviews Cancer October (2001) A Perspectives article about the prescient theories of the German geneticist Theodor Boveri, who foreshadowed several concepts and technical innovations that have emerged in modern cancer research.

A new verdict for an old convict. Pfeifer, G. P. Nature Genetics September (2001) A News and Views article on a study showing that the tumorigenic properties of mutant Kras in rodents — previously assumed to be a dominant oncogene — are, in fact, caused by the loss of a tumour-suppressor function.

RNA interference: listening to the sound of silence. Zamore, P. D. Nature Structural Biology September (2001)