Tumour Microenvironment

Throughout 2006 and 2007, a series of articles on the Tumour Microenvironment was published in Nature Reviews Cancer. The study of the tumour microenvironment involves a multidisciplinary approach, with in vitro and in vivo models of tumour growth, invasion, extracellular matrix remodelling, angiogenesis and inflammation, as well as preclinical trials, all contributing to the rapid progress that is being made in this area. We hope that this series of articles gave you a taste of the diversity of topics that form part of this rapidly moving field.


2007

October 2007 v7 n10

Emerging roles of proteases in tumour suppression

Carlos López-Otín & Lynn M. Matrisian

doi:10.1038/nrc2228

October 2007 v7 n10

Making a tumour's bed: glioblastoma stem cells and the vascular niche

Richard J. Gilbertson & Jeremy N. Rich

doi:10.1038/nrc2246

June 2007 v7 n6

Morphogens, morphostats, microarchitecture and malignancy

John D. Potter

doi:10.1038/nrc2146

May 2007 v7 n5

Laminin 332 in squamous–cell carcinoma

M. Peter Marinkovich

doi:10.1038/nrc2089

February 2007 v7 n2

The tumour microenvironment as a target for chemoprevention

Adriana Albini and Michael B. Sporn

doi:10.1038/nrc2067

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2006

October 2006 Vol 6 No 10

Cysteine cathepsins: multifunctional enzymes in cancer

Mona Mostafa Mohamed & Bonnie F. Sloane

August 2006 Vol 6 No 8

Targeting the mechanisms of tumoral immune tolerance with small-molecule inhibitors

Alexander J. Muller & Peggy A. Scherle

August 2006 Vol 6 No 8

Drug penetration in solid tumours

Andrew I. Minchinton & Ian F. Tannock

July 2006 Vol 6 No 7

Tumour microenvironment: TGFβ: the molecular Jekyll and Hyde of cancer

Brian Bierie & Harold L. Moses

May 2006 Vol 6 No 5

Fibroblasts in cancer

Raghu Kalluri & Michael Zeisberg

April 2006 Vol 6 No 4

Pregnancy-associated breast cancer and metastasis

Pepper Schedin

March 2006 Vol 6 No 3

Tumour microenvironment − Opinion: Validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy

Christopher M. Overall & Oded Kleifeld


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