Advance online publication
The latest articles published online ahead of print. These online versions are definitive and may be cited using the digital object identifier (DOI).
Article Types
Research Highlights
Microenvironment: What do your surroundings mean? | PDF (446 KB)
Published online: 15 May 2008 | doi:10.1038/nrc2409
Cell signalling: Dynamic redistribution | PDF (417 KB)
Published online: 15 May 2008 | doi:10.1038/nrc2408
Therapy: Reversed protection | PDF (170 KB)
Published online: 12 May 2008 | doi:10.1038/nrc2406
Imaging: Early detection for pancreatic cancer | PDF (189 KB)
Published online: 12 May 2008 | doi:10.1038/nrc2407
Oncogenesis: A sideways move? | PDF (212 KB)
Published online: 12 May 2008 | doi:10.1038/nrc2405
Review
Colonic crypt organization and tumorigenesis
Adam Humphries & Nicholas A. Wright
Published online: 15 May 2008 | doi:10.1038/nrc2392
Recent advances in our understanding of intestinal crypt biology, including how mutations in stem cells become fixed and expand within the epithelium, has led to new theories on the origins of colonic adenomas and cancers.
Perspectives
Timeline
Paul Ehrlich's magic bullet concept: 100 years of progress
Klaus Strebhardt & Axel Ullrich
Published online: 12 May 2008 | doi:10.1038/nrc2394
One hundred years ago, Paul Ehrlich received the Nobel Prize for Physiology or Medicine. His idea of creating 'magic bullets' for use in the fight against human diseases has inspired generations of scientists to devise powerful molecular cancer therapeutics.
Science and society
Heavy ion carcinogenesis and human space exploration
Marco Durante & Francis A. Cucinotta
Published online: 02 May 2008 | doi:10.1038/nrc2391
The next generation of space missions will involve much longer exposures of astronauts to space radiation. Predicting what this means for cancer risk is a crucial but difficult task.
Innovation
The Mouse Tumor Biology database
Debra M. Krupke, Dale A. Begley, John P. Sundberg, Carol J. Bult & Janan T. Eppig
Published online: 24 April 2008 | doi:10.1038/nrc2390
The Mouse Tumor Biology database seeks to facilitate the researcher's access to the ever increasing amount of data now being published using mouse models of cancer. Why is this database important and how does it relate to similar databases within the cancer research community?
About AOP
Until print versions of AOP papers are published, they should be cited in the style "Nature Reviews Cancer AOP, published online day month year; doi:10.1038/nrcXXX". Once the print version (identical to the AOP) is published, it should be cited as follows: "Nature Reviews Cancer volume number, page range (year); doi:10.1038/nrcXXX".