Focus
Immune Signaling Cross-talk
- Focus issue:
- April 2009 Volume 10, No 4
Five specially commissioned articles focus on the complex interplay among signaling pathways operative in immune cells.
Editorial
Focus on Immune Signaling Cross-talk
Embrace the complexity - p325
doi:10.1038/ni0409-325
Immune cell signal transduction is just too complicated to be effectively queried using traditional methods and mindsets.
Full Text - Embrace the complexity | PDF (215 KB) - Embrace the complexity
Overview
Focus on Immune Signaling Cross-talk
Navigating the network: signaling cross-talk in hematopoietic cells - pp327 - 331
Iain D C Fraser & Ronald N Germain
doi:10.1038/ni.1711
Abstract - | Full Text - Navigating the network: signaling cross-talk in hematopoietic cells | PDF (531 KB) - Navigating the network: signaling cross-talk in hematopoietic cells
Reviews
Focus on Immune Signaling Cross-talk
Integration of cytokine and heterologous receptor signaling pathways - pp333 - 339
Jelena S Bezbradica & Ruslan Medzhitov
doi:10.1038/ni.1713
Abstract - | Full Text - Integration of cytokine and heterologous receptor signaling pathways | PDF (1,244 KB) - Integration of cytokine and heterologous receptor signaling pathways
Focus on Immune Signaling Cross-talk
Cross-regulation of signaling by ITAM-associated receptors - pp340 - 347
Lionel B Ivashkiv
doi:10.1038/ni.1706
Abstract - | Full Text - Cross-regulation of signaling by ITAM-associated receptors | PDF (508 KB) - Cross-regulation of signaling by ITAM-associated receptors
Focus on Immune Signaling Cross-talk
Death receptor signal transducers: nodes of coordination in immune signaling networks - pp348 - 355
Nicholas S Wilson, Vishva Dixit & Avi Ashkenazi
doi:10.1038/ni.1714
Abstract - | Full Text - Death receptor signal transducers: nodes of coordination in immune signaling networks | PDF (672 KB) - Death receptor signal transducers: nodes of coordination in immune signaling networks
Perspectives
Focus on Immune Signaling Cross-talk
Selectivity and therapeutic inhibition of kinases: to be or not to be? - pp356 - 360
Kamran Ghoreschi, Arian Laurence & John J O'Shea
doi:10.1038/ni.1701
Abstract - | Full Text - Selectivity and therapeutic inhibition of kinases: to be or not to be? | PDF (470 KB) - Selectivity and therapeutic inhibition of kinases: to be or not to be?
Focus on Immune Signaling Cross-talk
Lymphocyte signaling: beyond knockouts - pp361 - 364
Alexander Saveliev & Victor L J Tybulewicz
doi:10.1038/ni.1709
Abstract - | Full Text - Lymphocyte signaling: beyond knockouts | PDF (428 KB) - Lymphocyte signaling: beyond knockouts
Research Highlights
Focus on Immune Signaling Cross-talk
Research Highlights - p365
doi:10.1038/ni0409-365
Full Text - Research Highlights | PDF (288 KB) - Research Highlights