Nature Immunology - Current issue : December 2009 - Vol 10 No 12
Latest highlights
Article of the month
Layered memory
Article by DoganImmunization elicits B cell memory and short- and long-term antibody-secreting plasma cells. Weill and colleagues show that long-term IgM+ and IgG+ memory B cells can persist in germinal centers and undergo different fates after antigenic rechallenge.
Announcement
Editorial position available
Nature Immunology seeks an Assistant Editor to join their editorial team. Candidates should have a broad interest in science and have expertise in any of the areas covered in Nature Immunology, especially innate immunity.
Applicants should submit a Curriculum Vitae, an editorial (900 words), and a cover letter explaining their interest in the position to admin@us.nature.com
Advance online publication
Multitasking RIG-I
Article by PoeckProduction of mature interleukin 1β (IL-1β) requires Il1b transcription and inflammasome-mediated processing of IL-1β protein. Ruland and colleagues show that the RNA virus sensor RIG-I signals via the adaptors CARD9 and Asc to facilitate both processes.
Current issue
Nod2 in T cells
Article by ShawNod2 senses intracellular bacteria and is required for their eradication. Nuñez and co-workers now describe a T cell-intrinsic role for Nod2 in combating the intracellular parasite Toxoplasma gondii.
See also:
News & Views by Salek-Ardakani & CroftCurrent issue
IL-17RA-IL-17 structure
Article by ElyThe interleukin 17 (IL-17) family includes six cytokines and five receptors. Garcia and co-workers solve the crystal structure of the receptor IL-17RA bound to IL-17F and suggest that IL-17RA may act as a shared subunit among multiple IL-17 receptor complexes.
Announcement
The Fondation IPSEN, Nature Immunology and Nature Reviews Molecular Cell Biology are pleased to announce an Emergence & Convergence mini-symposium:
Epigenetic Dynamics in the Immune System
February 19, 2010, The St. Anthony, San Antonio, TX, USA
For more information and to register, visit http://www.nature.com/natureconferences
/eandc/epigimm/index.html.
