Nature Immunology - Current issue : December 2009 - Vol 10 No 12
Latest highlights
Article of the month
Layered memory
Article by DoganImmunization elicits B cell memory and short- and long-term antibody-secreting plasma cells. Weill and colleagues show that long-term IgM+ and IgG+ memory B cells can persist in germinal centers and undergo different fates after antigenic rechallenge.
Announcement
Editorial position available
Nature Immunology seeks an Assistant Editor to join their editorial team. Candidates should have a broad interest in science and have expertise in any of the areas covered in Nature Immunology, especially innate immunity.
Applicants should submit a Curriculum Vitae, an editorial (900 words), and a cover letter explaining their interest in the position to admin@us.nature.com
Advance online publication
CD4 memory
Article by PepperNaive CD4+ T cells can differentiate into distinct polarized effector cells, but detailed characterization of physiologic CD4 memory is lacking. Jenkins and colleagues show that TH1 and TH17 memory cells differ in longevity and arise via different infection routes.
Current issue
MicroRNA managing TH-17 cells
Article by DuTH-17 cells are associated with multiple sclerosis (MS) pathogenesis. Pei and colleagues have now identified a TH-17 cell-associated microRNA, miR-326, whose expression correlates with disease severity.
See also:
News & Views by Martin, Zhou & MillerCurrent issue
Dec2 drives TH2 responses
Article by YangThe molecular mediators responsible for directing T helper type 2 (TH2) differentiation remain incompletely defined. Dong and co-workers find that the transcription factor Dec2 promotes expression of the transcription factor JunB and is essential for the induction of TH2 responses.
Announcement
The Fondation IPSEN, Nature Immunology and Nature Reviews Molecular Cell Biology are pleased to announce an Emergence & Convergence mini-symposium:
Epigenetic Dynamics in the Immune System
February 19, 2010, The St. Anthony, San Antonio, TX, USA
For more information and to register, visit http://www.nature.com/natureconferences
/eandc/epigimm/index.html.
