Letter to the Editor
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Open Access
Featured
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Genetics and Genomics
| Open AccessThe impact of a BRCA2 mutation on mortality from screen-detected prostate cancer
- M R Akbari
- , C J D Wallis
- & R K Nam
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Clinical Study
| Open AccessOverall survival and clinical characteristics of pancreatic cancer in BRCA mutation carriers
- T Golan
- , Z S Kanji
- & S Gallinger
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Molecular Diagnostics
| Open AccessUnique volatolomic signatures of TP53 and KRAS in lung cells
- M P A Davies
- , O Barash
- & H Haick
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Clinical Study
| Open AccessThe multigene signature MammaPrint impacts on multidisciplinary team decisions in ER+, HER2− early breast cancer
- R Exner
- , Z Bago-Horvath
- & P Dubsky
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Genetics and Genomics
| Open AccessAssessing standardization of molecular testing for non-small-cell lung cancer: results of a worldwide external quality assessment (EQA) scheme for EGFR mutation testing
- S Patton
- , N Normanno
- & E Thunnissen
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Reply to Letter to the Editor
| Open AccessReply: Intra-patient heterogeneity of BRAF mutation status: fact or fiction?
- L Heinzerling
- , G Schuler
- & R Schneider-Stock
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Molecular Diagnostics
| Open AccessDiscriminating metastasised from non-metastasised seminoma based on transcriptional changes in primary tumours using NGS
- C G Ruf
- , H-U Schmelz
- & M Abend
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Epidemiology
| Open AccessCoexistence of EGFR with KRAS, or BRAF, or PIK3CA somatic mutations in lung cancer: a comprehensive mutation profiling from 5125 Chinese cohorts
- S Li
- , L Li
- & N Liang
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Clinical Study
| Open AccessA feasibility study testing four hypotheses with phase II outcomes in advanced colorectal cancer (MRC FOCUS3): a model for randomised controlled trials in the era of personalised medicine?
- T S Maughan
- , A M Meade
- & R Kaplan
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Letter to the Editor
| Open AccessComment on ‘The NQO1 polymorphism C609T (Pro187Ser) and cancer susceptibility: a comprehensive meta-analysis’
- M A Malik
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Letter to the Editor
| Open AccessReply: Comment on ‘The NQO1 polymorphism C609T (Pro187Ser) and cancer susceptibility: a comprehensive meta-analysis’
- B Lajin
- & A Alachkar
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Mini Review
| Open AccessPrevalence and implications of elevated microsatellite alterations at selected tetranucleotides in cancer
- M M C Watson
- , M Berg
- & K Søreide
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Genetics and Genomics
| Open AccessErroneous identification of APOBEC3-edited chromosomal DNA in cancer genomics
- R Suspène
- , V Caval
- & J-P Vartanian
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Short Communication
| Open AccessMutation analysis of components of the Mediator kinase module in MED12 mutation-negative uterine leiomyomas
- N Mäkinen
- , H-R Heinonen
- & L A Aaltonen
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Genetics and Genomics
| Open AccessPrognostic impact of genomic instability in colorectal cancer
- T S Hveem
- , M A Merok
- & H E Danielsen
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Genetics and Genomics
| Open AccessLINE-1 methylation in leukocyte DNA, interaction with phosphatidylethanolamine N-methyltransferase variants and bladder cancer risk
- S M Tajuddin
- , A F S Amaral
- & J Mosquera
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Molecular Diagnostics
| Open AccessClinicopathological and prognostic significance of interleukin-8 expression and its relationship to KRAS mutation in lung adenocarcinoma
- N Sunaga
- , K Kaira
- & M Yamada
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Genetics and Genomics
| Open AccessFGF receptor genes and breast cancer susceptibility: results from the Breast Cancer Association Consortium
- D Agarwal
- , S Pineda
- & R L Milne
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Molecular Diagnostics
| Open AccessGene expression profiling reveals GC and CEACAM1 as new tools in the diagnosis of lung carcinoids
- F Toffalorio
- , E Belloni
- & T De Pas
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Molecular Diagnostics
| Open AccessCorrelation between human papillomavirus and p16 overexpression in oropharyngeal tumours: a systematic review
- C Grønhøj Larsen
- , M Gyldenløve
- & C von Buchwald
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Genetics and Genomics
| Open AccessFocal amplification of the androgen receptor gene in hormone-naive human prostate cancer
- S Merson
- , Z H Yang
- & J P Clark
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Molecular Diagnostics
| Open AccessFGFR2 amplification has prognostic significance in gastric cancer: results from a large international multicentre study
- X Su
- , P Zhan
- & E Kilgour
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Letter to the Editor
| Open AccessDistribution of breast cancer risk from SNPs and classical risk factors in women of routine screening age in the UK
- A R Brentnall
- , D G Evans
- & J Cuzick
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Genetics and Genomics
| Open AccessHost genetic variants of ABCB1 and IL15 influence treatment outcome in paediatric acute lymphoblastic leukaemia
- Y Lu
- , S K Y Kham
- & A E J Yeoh
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Molecular Diagnostics
| Open AccessMolecular heterogeneity and prognostic implications of synchronous advanced colorectal neoplasia
- A Malesci
- , G Basso
- & L Laghi
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Genetics and Genomics
| Open AccessMutation frequencies of GNAQ, GNA11, BAP1, SF3B1, EIF1AX and TERT in uveal melanoma: detection of an activating mutation in the TERT gene promoter in a single case of uveal melanoma
- M Dono
- , G Angelini
- & U Pfeffer
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Molecular Diagnostics
| Open AccessTriple negative breast carcinoma EGFR amplification is not associated with EGFR, Kras or ALK mutations
- V Secq
- , J Villeret
- & C Charpin
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Genetics and Genomics
| Open AccessImpact of rapid genetic counselling and testing on the decision to undergo immediate or delayed prophylactic mastectomy in newly diagnosed breast cancer patients: findings from a randomised controlled trial
- M R Wevers
- , N K Aaronson
- & M G E M Ausems
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Letter to the Editor
| Open AccessIntra-patient heterogeneity of BRAF mutation status: fact or fiction?
- A M Menzies
- , J S Wilmott
- & R A Scolyer
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Short Communication
| Open AccessGermline CDH1 mutations in bilateral lobular carcinoma in situ
- C Petridis
- , I Shinomiya
- & E J Sawyer
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Molecular Diagnostics
| Open AccessIGFBP7 is associated with poor prognosis in oesophageal adenocarcinoma and is regulated by promoter DNA methylation
- E Smith
- , A R Ruszkiewicz
- & P A Drew
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Genetics and Genomics
| Open AccessHBx mutants differentially affect the activation of hypoxia-inducible factor-1α in hepatocellular carcinoma
- L-p Liu
- , B-g Hu
- & P B S Lai
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Genetics and Genomics
| Open AccessKey differences identified between actinic keratosis and cutaneous squamous cell carcinoma by transcriptome profiling
- S R Lambert
- , N Mladkova
- & C A Harwood
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Genetics and Genomics
| Open AccessAn RNAi-based screen reveals PLK1, CDK1 and NDC80 as potential therapeutic targets in malignant pleural mesothelioma
- A Linton
- , Y Y Cheng
- & G Reid
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Genetics and Genomics
| Open AccessIncidence of colorectal cancer in BRCA1 and BRCA2 mutation carriers: results from a follow-up study
- C M Phelan
- , J Iqbal
- & Tomasz Huzarski
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Molecular Diagnostics
| Open AccessEvidence that active demethylation mechanisms maintain the genome of carcinoma in situ cells hypomethylated in the adult testis
- D G Kristensen
- , J E Nielsen
- & K Almstrup
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Molecular Diagnostics
| Open AccessCollagen type XI α1 facilitates head and neck squamous cell cancer growth and invasion
- J C Sok
- , J A Lee
- & S M Thomas
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Molecular Diagnostics
| Open AccessEpigenetic status of LINE-1 predicts clinical outcome in early-stage rectal cancer
- A Benard
- , C J H van de Velde
- & D S B Hoon
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Molecular Diagnostics
| Open AccessMutation landscape in melanoma patients clinical implications of heterogeneity of BRAF mutations
- L Heinzerling
- , M Baiter
- & R Schneider-Stock
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Molecular Diagnostics
| Open AccessExpression of nuclear survivin in normal skin and squamous cell carcinoma: a possible role in tumour invasion
- K Dallaglio
- , T Petrachi
- & C Pincelli
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Genetics and Genomics
| Open AccessStrong reduction of AGO2 expression in melanoma and cellular consequences
- D Völler
- , J Reinders
- & A-K Bosserhoff
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Genetics and Genomics
| Open AccessGenetic variation in the GSTM3 promoter confer risk and prognosis of renal cell carcinoma by reducing gene expression
- X Tan
- , Y Wang
- & G Cao
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Genetics and Genomics
| Open AccessDICER1 hotspot mutations in non-epithelial gonadal tumours
- L Witkowski
- , J Mattina
- & W D Foulkes
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Molecular Diagnostics
| Open AccessSILAC-based phosphoproteomics reveals an inhibitory role of KSR1 in p53 transcriptional activity via modulation of DBC1
- H Zhang
- , Y Xu
- & G Giamas
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Genetics and Genomics
| Open AccessMicroRNA-based molecular classification of non-BRCA1/2 hereditary breast tumours
- M Tanic
- , E Andrés
- & B Martinez-Delgado
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Genetics and Genomics
| Open AccessIodine-131 dose-dependent gene expression: alterations in both normal and tumour thyroid tissues of post-Chernobyl thyroid cancers
- M Abend
- , R M Pfeiffer
- & A V Brenner
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Translational Therapeutics
| Open AccessAerosolised 5-azacytidine suppresses tumour growth and reprogrammes the epigenome in an orthotopic lung cancer model
- M D Reed
- , C S Tellez
- & S A Belinsky
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Molecular Diagnostics
| Open AccessEGFR mutational status in a large series of Caucasian European NSCLC patients: data from daily practice
- S Gahr
- , R Stoehr
- & W Dietmaier
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