Featured
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Brief Communication
| Open AccessWhole-exome sequencing of long-term, never relapse exceptional responders of trastuzumab-treated HER2+ metastatic breast cancer
- Naomi Walsh
- , Charlotte Andrieu
- & John Crown
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Correspondence
| Open AccessComment on: “UGT2B17 modifies drug response in chronic lymphocytic leukaemia”
- Spyros I. Papamichos
- & Christof Jungbauer
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Article
| Open AccessComputational analysis of TP53 mutational landscape unveils key prognostic signatures and distinct pathobiological pathways in head and neck squamous cell cancer
- Vito Carlo Alberto Caponio
- , Giuseppe Troiano
- & Lorenzo Lo Muzio
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Article
| Open AccessCytochrome P450 1B1 polymorphism drives cancer cell stemness and patient outcome in head-and-neck carcinoma
- Valérie Le Morvan
- , Élodie Richard
- & Jacques Robert
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Review Article
| Open AccessEmerging role of PTEN loss in evasion of the immune response to tumours
- Thiago Vidotto
- , Camila Morais Melo
- & Jeremy A. Squire
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Article
| Open AccessAddition of an online, validated family history questionnaire to the Dutch FIT-based screening programme did not improve its diagnostic yield
- Victorine H. Roos
- , Frank G. J. Kallenberg
- & Evelien Dekker
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Review Article
| Open AccessIDH mutation in glioma: molecular mechanisms and potential therapeutic targets
- Sue Han
- , Yang Liu
- & Chunzhang Yang
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Article
| Open AccessReversal of glucocorticoid resistance in paediatric acute lymphoblastic leukaemia is dependent on restoring BIM expression
- Cara E. Toscan
- , Duohui Jing
- & Richard B. Lock
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Article
| Open AccessA common polymorphism in the retinoic acid pathway modifies adrenocortical carcinoma age-dependent incidence
- Mirvat Surakhy
- , Marsha Wallace
- & Gareth L. Bond
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Article
| Open AccessGenomic profiling of multiple breast cancer reveals inter-lesional heterogeneity
- Soomin Ahn
- , Hyun Jeong Kim
- & So Yeon Park
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Article
| Open AccessA key genomic subtype associated with lymphovascular invasion in invasive breast cancer
- Sasagu Kurozumi
- , Chitra Joseph
- & Emad A Rakha
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Editorial
| Open AccessMoving from one to many: insights from the growing list of pleiotropic cancer risk genes
- Stephanie A. Bien
- & Ulrike Peters
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Article
| Open AccessExome and immune cell score analyses reveal great variation within synchronous primary colorectal cancers
- Ulrika A. Hänninen
- , Erkki-Ville Wirta
- & Lauri A. Aaltonen
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Article
| Open AccessThe clinical relevance of multiple DPYD polymorphisms on patients candidate for fluoropyrimidine based-chemotherapy. An Italian case-control study
- Francesco Iachetta
- , Candida Bonelli
- & Carmine Pinto
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Article
| Open AccessA novel approach to modelling transcriptional heterogeneity identifies the oncogene candidate CBX2 in invasive breast carcinoma
- Daniel G. Piqué
- , Cristina Montagna
- & Jessica C. Mar
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Article
| Open AccessGenome-wide association study of germline variants and breast cancer-specific mortality
- Maria Escala-Garcia
- , Qi Guo
- & Marjanka K. Schmidt
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Article
| Open AccessOestrogen receptor status and survival in women with BRCA2-associated breast cancer
- Kelly Metcalfe
- , Henry T. Lynch
- & Steven A. Narod
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Article
| Open AccessEarly immune modulation by single-agent trastuzumab as a marker of trastuzumab benefit
- Tiziana Triulzi
- , Viola Regondi
- & Elda Tagliabue
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Article
| Open AccessBcl-2-dependent synthetic lethal interaction of the IDF-11774 with the V0 subunit C of vacuolar ATPase (ATP6V0C) in colorectal cancer
- Bo-Kyung Kim
- , Soon Woo Nam
- & Misun Won
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Article
| Open AccessWT1 expression in vessels varies with histopathological grade in tumour-bearing and control tissue from patients with breast cancer
- Richard J. McGregor
- , You-Ying Chau
- & Patrick W. F. Hadoke
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Article
| Open AccessCandidate biomarkers of PARP inhibitor sensitivity in ovarian cancer beyond the BRCA genes
- Darren R. Hodgson
- , Brian A. Dougherty
- & J. Carl Barrett
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Article
| Open AccessTarget-based therapeutic matching of phase I trials in patients with metastatic breast cancer in a tertiary referral centre
- Brent O’Carrigan
- , Joline Si Jing Lim
- & Timothy Anthony Yap
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Article
| Open AccessPhenotype-independent DNA methylation changes in prostate cancer
- Davide Pellacani
- , Alastair P. Droop
- & Norman J. Maitland
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Editorial |
Moving the needle on colorectal cancer genetics: it takes more than two to TANGO
- Luis G. Carvajal-Carmona
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Article
| Open AccessColon-specific eQTL analysis to inform on functional SNPs
- Victor Moreno
- , M. Henar Alonso
- & Xavier Solé
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Article
| Open AccessConstitutively active androgen receptor splice variants AR-V3, AR-V7 and AR-V9 are co-expressed in castration-resistant prostate cancer metastases
- Heini M. L. Kallio
- , Reija Hieta
- & Tapio Visakorpi
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Article
| Open AccessHeterogeneous MYCN amplification in neuroblastoma: a SIOP Europe Neuroblastoma Study
- Ana P. Berbegall
- , Dominik Bogen
- & Inge M. Ambros
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Article
| Open AccessTumour mutation status and melanoma recurrence following a negative sentinel lymph node biopsy
- Nikki R. Adler
- , Rory Wolfe
- & Victoria J. Mar
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Review Article
| Open AccessCutaneous neurofibromas in the genomics era: current understanding and open questions
- Robert J. Allaway
- , Sara J. C. Gosline
- & Lu Q. Le
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Article
| Open AccessAn integrative bioinformatics approach reveals coding and non-coding gene variants associated with gene expression profiles and outcome in breast cancer molecular subtypes
- Balázs Győrffy
- , Lőrinc Pongor
- & Libero Santarpia
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Genetics and Genomics
| Open AccessGlobal metabolomic profiling of uterine leiomyomas
- Hanna-Riikka Heinonen
- , Miika Mehine
- & Eevi Kaasinen
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Genetics and Genomics
| Open AccessAssociations of Helicobacter pylori infection and chronic atrophic gastritis with accelerated epigenetic ageing in older adults
- Xu Gao
- , Yan Zhang
- & Hermann Brenner
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Short Communication
| Open AccessFfar2 expression regulates leukaemic cell growth in vivo
- Laure B Bindels
- , Paolo E Porporato
- & Nathalie M Delzenne
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Genetics and Genomics
| Open AccessCharacterisation of the novel deleterious RAD51C p.Arg312Trp variant and prioritisation criteria for functional analysis of RAD51C missense changes
- Javier Gayarre
- , Paloma Martín-Gimeno
- & María J García
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Genetics and Genomics
| Open AccessGNAQ and GNA11 mutations and downstream YAP activation in choroidal nevi
- M J C Vader
- , M C Madigan
- & P A van der Velden
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Genetics and Genomics
| Open AccessA comparative study of germline BRCA1 and BRCA2 mutation screening methods in use in 20 European clinical diagnostic laboratories
- Gillian Ellison
- , Andrew Wallace
- & Simon Patton
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Genetics and Genomics
| Open AccessEvidence for genetic association between chromosome 1q loci and predisposition to colorectal neoplasia
- Stephanie A Schubert
- , Dina Ruano
- & Tom van Wezel
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Genetics and Genomics
| Open AccessWhole-genome sequencing revealed novel prognostic biomarkers and promising targets for therapy of ovarian clear cell carcinoma
- Hiroaki Itamochi
- , Tetsuro Oishi
- & Toru Sugiyama
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Genetics and Genomics
| Open AccessClinical study of genomic drivers in pancreatic ductal adenocarcinoma
- Michael T Barrett
- , Ray Deiotte
- & Daniel D Von Hoff
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Genetics and Genomics
| Open AccessNon-invasive prediction of recurrence in bladder cancer by detecting somatic TERT promoter mutations in urine
- Françoise Descotes
- , Norelyakin Kara
- & Alain Ruffion
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Genetics and Genomics
| Open AccessComprehensive analysis of copy number aberrations in microsatellite stable colon cancer in view of stromal component
- M Henar Alonso
- , Susanna Aussó
- & Victor Moreno
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Genetics and Genomics
| Open AccessImpact of novel miR-145-3p regulatory networks on survival in patients with castration-resistant prostate cancer
- Yusuke Goto
- , Akira Kurozumi
- & Naohiko Seki
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Clinical Study
| Open AccessThe role of primary tumour sidedness, EGFR gene copy number and EGFR promoter methylation in RAS/BRAF wild-type colorectal cancer patients receiving irinotecan/cetuximab
- Laura Demurtas
- , Marco Puzzoni
- & Mario Scartozzi
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Translational Therapeutics
| Open AccessMolecular profiling of signet ring cell colorectal cancer provides a strong rationale for genomic targeted and immune checkpoint inhibitor therapies
- Muhammad A Alvi
- , Maurice B Loughrey
- & Manuel Salto-Tellez
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Molecular Diagnostics
| Open AccessPrevalence of somatic mitochondrial mutations and spatial distribution of mitochondria in non-small cell lung cancer
- Daniel Kazdal
- , Alexander Harms
- & Arne Warth
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Genetics and Genomics
| Open AccessA meta-analysis of CXCL12 expression for cancer prognosis
- Harsh Samarendra
- , Keaton Jones
- & Alex Gordon-Weeks
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Genetics and Genomics
| Open AccessSequencing of DICER1 in sarcomas identifies biallelic somatic DICER1 mutations in an adult-onset embryonal rhabdomyosarcoma
- Leanne de Kock
- , Barbara Rivera
- & William D Foulkes
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Molecular Diagnostics
| Open AccessMutation status among patients with sinonasal mucosal melanoma and its impact on survival
- Moran Amit
- , Samantha Tam
- & Ehab Y Hanna
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