Featured
-
-
Article
| Open AccessImpact of KRAS, BRAF and microsatellite instability status after cytoreductive surgery and HIPEC in a national cohort of colorectal peritoneal metastasis patients
- S. G. Larsen
- , M. A. Goscinski
- & H. Sorbye
-
Article |
Variant allele frequency in baseline circulating tumour DNA to measure tumour burden and to stratify outcomes in patients with RAS wild-type metastatic colorectal cancer: a translational objective of the Valentino study
- Paolo Manca
- , Salvatore Corallo
- & Filippo Pietrantonio
-
Article |
High PGD2 receptor 2 levels are associated with poor prognosis in colorectal cancer patients and induce VEGF expression in colon cancer cells and migration in a zebrafish xenograft model
- Pujarini Dash
- , Souvik Ghatak
- & Anita Sjölander
-
Article
| Open AccessDo presenting symptoms, use of pre-diagnostic endoscopy and risk of emergency cancer diagnosis vary by comorbidity burden and type in patients with colorectal cancer?
- Sara Benitez Majano
- , Georgios Lyratzopoulos
- & Cristina Renzi
-
Article
| Open AccessA stem cell marker KLF5 regulates CCAT1 via three-dimensional genome structure in colorectal cancer cells
- Takashi Takeda
- , Yuhki Yokoyama
- & Hirofumi Yamamoto
-
Article |
Statin use is associated with a reduced incidence of colorectal cancer expressing SMAD4
- Sarah Ouahoud
- , Rutger J. Jacobs
- & James C. H. Hardwick
-
Article |
Mitochondrial matrix protein C14orf159 attenuates colorectal cancer metastasis by suppressing Wnt/β-catenin signalling
- Kenji Ohshima
- , Ryo Oi
- & Eiichi Morii
-
Article |
Germline polymorphisms in genes maintaining the replication fork predict the efficacy of oxaliplatin and irinotecan in patients with metastatic colorectal cancer
- Hiroyuki Arai
- , Yi Xiao
- & Heinz-Josef Lenz
-
Article |
Prognostic role of tumour-infiltrating lymphocytes and macrophages in relation to MSI, CDX2 and BRAF status: a population-based study of metastatic colorectal cancer patients
- Kristine Aasebø
- , Jarle Bruun
- & Halfdan Sorbye
-
Article |
Significant decrease in interval colorectal cancer incidence after implementing immunochemical testing in a multiple-round guaiac-based screening programme
- Jean-François Bretagne
- , Aurore Carlo
- & Astrid Lièvre
-
Perspective
| Open AccessHighlights from ASCO-GI 2021 from EORTC Gastrointestinal tract cancer group
- Thibaud Koessler
- , Maria Alsina
- & Markus Moehler
-
Review Article
| Open AccessThe therapeutic and prognostic implications of immunobiology in colorectal cancer: a review
- Alexandra M. Zaborowski
- , Des C. Winter
- & Lydia Lynch
-
Article |
Clinical impact of PET/MRI in oligometastatic colorectal cancer
- Felipe S. Furtado
- , Krista E. Suarez-Weiss
- & Onofrio A. Catalano
-
Article |
Sugar-sweetened beverage, artificially sweetened beverage and sugar intake and colorectal cancer survival
- Emilie S. Zoltick
- , Stephanie A. Smith-Warner
- & Kana Wu
-
Article |
CEA increase as a marker of disease progression after first-line induction therapy in metastatic colorectal cancer patients. A pooled analysis of TRIBE and TRIBE2 studies
- Roberto Moretto
- , Daniele Rossini
- & Chiara Cremolini
-
Article
| Open AccessMolecular subtype-specific efficacy of anti-EGFR therapy in colorectal cancer is dependent on the chemotherapy backbone
- Sanne ten Hoorn
- , Dirkje W. Sommeijer
- & Louis Vermeulen
-
Article |
Association between post-treatment circulating biomarkers of inflammation and survival among stage II–III colorectal cancer patients
- Xinwei Hua
- , Mario Kratz
- & Polly A. Newcomb
-
Article
| Open AccessThe efficacy of anti-EGFR therapy in treating metastatic colorectal cancer differs between the middle/low rectum and the left-sided colon
- Kun-Han Lee
- , Wei-Shone Chen
- & Hao-Wei Teng
-
Article
| Open AccessS100P contributes to promoter demethylation and transcriptional activation of SLC2A5 to promote metastasis in colorectal cancer
- Mingdao Lin
- , Yuan Fang
- & Haijun Deng
-
Article |
CEA, CA19-9, circulating DNA and circulating tumour cell kinetics in patients treated for metastatic colorectal cancer (mCRC)
- David Sefrioui
- , Ludivine Beaussire
- & Frédéric Di Fiore
-
Article |
Circulating tumour cells and cell-free DNA as a prognostic factor in metastatic colorectal cancer: the OMITERC prospective study
- Francesca Salvianti
- , Stefania Gelmini
- & Lorenzo Antonuzzo
-
Article |
Association between risk factors, molecular features and CpG island methylator phenotype colorectal cancer among different age groups in a Taiwanese cohort
- Kuo-Hsing Chen
- , Liang-In Lin
- & Kun-Huei Yeh
-
Article
| Open AccessThe circulating soluble form of the CD40 costimulatory immune checkpoint receptor and liver metastasis risk in rectal cancer
- Sebastian Meltzer
- , Annette Torgunrud
- & Anne Hansen Ree
-
Article |
A phase 1/2 trial of ibrutinib in combination with pembrolizumab in patients with mismatch repair proficient metastatic colorectal cancer
- Dae Won Kim
- , Elaine Tan
- & Richard D. Kim
-
Article
| Open AccessThe effect of geriatric intervention in frail older patients receiving chemotherapy for colorectal cancer: a randomised trial (GERICO)
- Cecilia Margareta Lund
- , Kirsten Kjeldgaard Vistisen
- & Dorte Lisbeth Nielsen
-
Article
| Open Access5-Aminosalicylic acid inhibits stem cell function in human adenoma-derived cells: implications for chemoprophylaxis in colorectal tumorigenesis
- Steven William Dixon
- , Tracey Jane Collard
- & Ann Caroline Williams
-
Article |
Aspirin reduces the incidence of metastasis in a pre-clinical study of Braf mutant serrated colorectal neoplasia
- Alexandra M. Kane
- , Cheng Liu
- & Vicki L. J. Whitehall
-
Article |
The prognostic value of combined measures of the systemic inflammatory response in patients with colon cancer: an analysis of 1700 patients
- Allan M. Golder
- , Donald C. McMillan
- & Campbell S. Roxburgh
-
Comment |
A bacterial mutational footprint in colorectal cancer genomes
- Axel Rosendahl Huber
- , Cayetano Pleguezuelos-Manzano
- & Jens Puschhof
-
Article |
Kinome-wide analysis of the effect of statins in colorectal cancer
- Sarah Ouahoud
- , Rutger J. Jacobs
- & James C. H. Hardwick
-
Article
| Open AccessPrognostic significance of interleukin-17A-producing colorectal tumour antigen-specific T cells
- Amanda Thomson
- , Diana F. Costa Bento
- & Andrew Godkin
-
Article
| Open AccessFrequent post-operative monitoring of colorectal cancer using individualised ctDNA validated by multiregional molecular profiling
- Mizunori Yaegashi
- , Takeshi Iwaya
- & Satoshi S. Nishizuka
-
Article
| Open AccessPharmaceutical immunoglobulin G impairs anti-carcinoma activity of oxaliplatin in colon cancer cells
- Yuru Shang
- , Xianbin Zhang
- & Michael Linnebacher
-
Article
| Open AccessGenetically predicted physical activity levels are associated with lower colorectal cancer risk: a Mendelian randomisation study
- Xiaomeng Zhang
- , Evropi Theodoratou
- & Maria Timofeeva
-
Article
| Open AccessLack of an association between gallstone disease and bilirubin levels with risk of colorectal cancer: a Mendelian randomisation analysis
- Richard Culliford
- , Alex J. Cornish
- & Richard S. Houlston
-
Article
| Open AccessPrognostic value of desmoplastic reaction characterisation in stage II colon cancer: prospective validation in a Phase 3 study (SACURA Trial)
- Hideki Ueno
- , Megumi Ishiguro
- & Kenichi Sugihara
-
Article
| Open AccessDairy intake during adolescence and risk of colorectal adenoma later in life
- Katharina Nimptsch
- , Dong Hoon Lee
- & Kana Wu
-
Article
| Open AccessCDX2 inhibits epithelial–mesenchymal transition in colorectal cancer by modulation of Snail expression and β-catenin stabilisation via transactivation of PTEN expression
- Junhui Yu
- , Shan Li
- & Xuejun Sun
-
Article
| Open AccessThe prognostic impact of RAS on overall survival following liver resection in early versus late-onset colorectal cancer patients
- Alexandre A. Jácome
- , Timothy J. Vreeland
- & Cathy Eng
-
Article
| Open AccessMutational profiles associated with resistance in patients with BRAFV600E mutant colorectal cancer treated with cetuximab and encorafenib +/− binimetinib or alpelisib
- Sanne C. F. A. Huijberts
- , Mirjam C. Boelens
- & Frans L. Opdam
-
Article
| Open AccessAPC loss induces Warburg effect via increased PKM2 transcription in colorectal cancer
- Pu-Hyeon Cha
- , Jeong-Ha Hwang
- & Kang-Yell Choi
-
Article
| Open AccessSurvival of patients with deficient mismatch repair metastatic colorectal cancer in the pre-immunotherapy era
- G. Emerens Wensink
- , Marloes A. G. Elferink
- & Miriam Koopman
-
Article
| Open AccessTreatments after progression to first-line FOLFOXIRI and bevacizumab in metastatic colorectal cancer: a pooled analysis of TRIBE and TRIBE2 studies by GONO
- Daniele Rossini
- , Sara Lonardi
- & Chiara Cremolini
-
Correspondence
| Open AccessReply to ‘Comment on “The myth of pulmonary metastasectomy’”
- Fergus Macbeth
- & Dame Lesley Fallowfield
-
Article
| Open AccessThe effect of vitamin D supplementation on survival in patients with colorectal cancer: systematic review and meta-analysis of randomised controlled trials
- Peter G. Vaughan-Shaw
- , Louis F. Buijs
- & Malcolm G. Dunlop
-
Article
| Open AccessPhase 2 study of irinotecan plus cetuximab rechallenge as third-line treatment in KRAS wild-type metastatic colorectal cancer: JACCRO CC-08
- Toshiki Masuishi
- , Akihito Tsuji
- & Masashi Fujii
-
Article
| Open AccessOne-year mortality of colorectal cancer patients: development and validation of a prediction model using linked national electronic data
- Thomas E. Cowling
- , Alexis Bellot
- & Jan van der Meulen
-
Article
| Open AccessAssociation between adjuvant chemotherapy and survival in patients with rectal cancer and pathological complete response after neoadjuvant chemoradiotherapy and resection
- Fang He
- , Huai-Qiang Ju
- & Xiang-Bo Wan
-
Article
| Open AccessImmune status is prognostic for poor survival in colorectal cancer patients and is associated with tumour hypoxia
- Stephanie G. Craig
- , Matthew P. Humphries
- & Manuel Salto-Tellez