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Cycling of the sulfur compound DMSOP by dimethylsulfoniopropionate lyase enzymes in the most abundant marine bacteria, algae and fungi is diverse and prevalent in Earth’s oceans and sediments and probably impacts climate-active gas production.
DNA analysis of ancient dental calculus samples revealed distinct oral microbial communities, including the archaeon Methanobrevibacter, which was associated with hygiene, diet and health.
On-farm experiments in 54 fields in Switzerland show that inoculation with arbuscular mycorrhizal fungi can promote crop yield, and inoculation success can be predicted using soil microbiome indicators.
Detection of GBS DNA in the placenta is associated with neonatal unit admission, infant morbidity and, in some cases, sepsis and foetal cytokine storm.
Evaluation of a nanopore-sequencing-based workflow for detection of antimalarial resistance in Ghana demonstrates feasibility where molecular surveillance is needed.
Counting the number of viable cells in a culture remains a critical measurement in microbiology, but traditional dilution assays are time- and reagent-consuming. We developed the geometric viability assay that overcomes these limitations by leveraging microbial colony distribution in a cone — a pipette tip — to calculate viability across six orders of magnitude.
A postnatal multiple micronutrient deficiency mouse model reveals shifts in bacterial, fungal and viral components of the gut microbiome with implications for microbiome-encoded intrinsic antibiotic resistance mechanisms.
Near-identical downy-mildew-associated microbiomes are recruited by infected Arabidopsis plants in different laboratories and reduce the impact of subsequent infection.
An analysis of over 2,000 genomes from Human Microbiome Project metagenomic data led to the identification of several extended- and narrow-spectrum antibiotics against clinical multidrug-resistant pathogens, including methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococci.
Using agar media suspended in pipette tips and a standard camera, the geometric viability assay provides a user-friendly and scalable update to standard colony-forming-unit-count approaches.
Empowering women through citizen science, from using self-collected vaginal samples to participant input on research questions, we decoded nuances in the composition of the vaginal microbiota — thereby linking female health and lifestyle to vaginal microbiota diversity. We crafted a unique dataset that should inspire new diagnostic and therapeutic opportunities.
Long-read sequencing and chromatin capture methods reveal that two nuclear genomes segregate among thousands of co-existing nuclei in arbuscular mycorrhizal fungi.