2022 Research Leaders: Leading healthcare institutions

The 2022 Research Leaders are based on Nature Index data from 1 January 2021 to 31 December 2021.

Table criteria

Position Institution Share 2020 Share 2021 Count 2021 Change in Adjusted Share* 2020–2021
1 The University of Texas Southwestern Medical Center (UT Southwestern Medical Center), United States of America (USA) 149.89 160.33 312 4.1% Increase
2 Massachusetts General Hospital (MGH), United States of America (USA) 91.16 98.18 604 4.8% Increase
3 Mount Sinai Health System (MSHS), United States of America (USA) 82.49 94.25 389 11.2% Increase
4 Memorial Sloan Kettering Cancer Center (MSKCC), United States of America (USA) 96.87 92.60 333 -7.0% Decrease
5 The University of Texas MD Anderson Cancer Center, United States of America (USA) 76.16 88.82 302 13.5% Increase
6 Brigham and Women's Hospital (BWH), United States of America (USA) 70.17 82.66 534 14.6% Increase
7 Columbia University Irving Medical Center (CUIMC), CU, United States of America (USA) 124.58 75.15 270 -41.3% Decrease
8 NYU Langone Health, United States of America (USA) 85.80 71.83 197 -18.5% Decrease
9 Mayo Clinic, United States of America (USA) 60.03 70.02 218 13.5% Increase
10 Dana-Farber Cancer Institute (DFCI), United States of America (USA) 59.29 60.61 460 -0.5% Decrease
11 Boston Children's Hospital (BCH), United States of America (USA) 55.21 58.70 384 3.4% Increase
12 St. Jude Children's Research Hospital (St. Jude), United States of America (USA) 46.01 57.33 127 21.2% Increase
13 Scientific Institute for Research, Hospitalization and Healthcare (IRCCS), Italy 44.61 50.38 273 9.9% Increase
14 West China School of Medicine/West China Hospital of Sichuan University (WCSM/WCH), SCU, China 26.11 47.46 118 76.9% Increase
15 UCLA Health, United States of America (USA) 70.05 42.44 195 -41.1% Decrease
16 Duke University Health System, United States of America (USA) 94.99 42.29 132 -56.7% Decrease
17 Vanderbilt University Medical Center (VUMC), United States of America (USA) 83.88 39.67 159 -54.0% Decrease
18 The University of Texas Health Science Center at Houston (UTHealth), United States of America (USA) 32.80 37.95 177 12.5% Increase
19 Renji Hospital, SJTU, China 37.06 36.30 133 -4.7% Decrease
20 Beth Israel Deaconess Medical Center (BIDMC), United States of America (USA) 32.74 32.92 297 -2.2% Decrease
21 Erasmus University Medical Center (Erasmus MC), Netherlands 24.06 32.59 163 31.8% Increase
22 University Health Network (UHN), U of T, Canada 24.85 30.89 125 20.9% Increase
23 UC San Diego Health Sciences, United States of America (USA) 104.27 27.00 137 -74.8% Decrease
24 Assistance Publique-Hôpitaux de Paris (AP-HP), France 21.90 25.51 238 13.3% Increase
25 Michigan Medicine, U-M, United States of America (USA) 113.24 24.83 94 -78.7% Decrease
26 Cincinnati Children's Hospital Medical Center (CCHMC), United States of America (USA) 34.16 24.81 109 -29.3% Decrease
27 University Medical Center Hamburg-Eppendorf (UKE), UHH, Germany 22.45 24.63 146 6.7% Increase
28 Children's Hospital of Philadelphia (CHOP), United States of America (USA) 23.74 24.44 141 0.1% Increase
29 Radboud University Medical Centre (Radboudumc), RU, Netherlands 22.44 24.28 149 5.3% Increase
30 Leiden University Medical Center (LUMC), Netherlands 27.54 24.15 131 -14.7% Decrease
31 University Medical Center Utrecht (UMC Utrecht), Netherlands 19.84 23.70 146 16.2% Increase
32 Cleveland Clinic, United States of America (USA) 30.09 22.40 96 -27.6% Decrease
33 University Medical Center Göttingen (UMG), Germany 16.50 21.95 104 29.5% Increase
34 The Hospital for Sick Children (SickKids), U of T, Canada 34.30 21.74 117 -38.3% Decrease
35 Sun Yat-sen University Cancer Center (SYSUCC), SYSU, China 11.91 21.65 68 76.8% Increase
36 City of Hope, United States of America (USA) 22.49 20.15 103 -12.8% Decrease
37 University Medical Center Groningen (UMCG), RUG, Netherlands 21.11 18.89 104 -13.0% Decrease
38 McGill University Health Centre (MUHC), Canada 16.78 18.52 83 7.4% Increase
39 UW Medicine, United States of America (USA) 83.91 17.85 103 -79.3% Decrease
40 VU University Medical Center (VUmc), Netherlands 18.22 17.75 170 -5.2% Decrease
41 Academic Medical Center (AMC), UvA, Netherlands 17.48 17.39 198 -3.2% Decrease
42 University of Pittsburgh Medical Center (UPMC), United States of America (USA) 10.51 17.11 98 58.4% Increase
43 Ruijin Hospital, SJTU, China 13.25 16.90 69 24.1% Increase
44 Cedars-Sinai Medical Center (Cedars-Sinai), United States of America (USA) 16.62 16.68 65 -2.3% Decrease
45 The University of Texas Health Science Center at San Antonio (UT Health San Antonio), United States of America (USA) 21.13 16.60 75 -23.6% Decrease
46 UCSF Health, United States of America (USA) 45.70 16.24 93 -65.4% Decrease
47 UNC Lineberger Comprehensive Cancer Center, United States of America (USA) 15.82 15.83 73 -2.7% Decrease
48 The Second Affiliated Hospital of Zhejiang University (SAHZU), ZJU, China 13.23 15.76 69 15.9% Increase
49 Fudan University Shanghai Cancer Center (FUSCC), China 7.18 15.60 58 111.5% Increase
50 Shanghai Tenth People's Hospital, Tongji University, China 6.24 15.55 58 142.5% Increase
51 Zhongshan Hospital, Fudan University, China 7.36 15.24 67 101.5% Increase
52 University Hospital of Lausanne (CHUV), UNIL, Switzerland 10.04 14.67 100 42.2% Increase
53 University of Nebraska Medical Center (UNMC), United States of America (USA) 19.04 14.65 35 -25.2% Decrease
54 H. Lee Moffitt Cancer Center & Research Institute, United States of America (USA) 16.31 14.47 53 -13.7% Decrease
55 The First Affiliated Hospital, USTC, China 4.51 14.27 47 207.7% Increase
56 University Medical Center Freiburg, Germany 10.53 13.94 75 28.8% Increase
57 Shanghai Ninth People's Hospital, SJTU, China 8.05 13.78 45 66.6% Increase
58 First Affiliated Hospital, ZJU, China 8.94 13.73 65 49.4% Increase
59 Hannover Medical School (MHH), Germany 16.99 13.68 123 -21.7% Decrease
60 Wuhan Union Hospital, HUST, China 5.25 13.46 52 149.3% Increase
61 University Hospital Zurich (UHZ), Switzerland 14.75 12.96 75 -14.5% Decrease
62 Seattle Children's Hospital, United States of America (USA) 7.35 12.42 77 64.4% Increase
63 Karolinska University Hospital, Sweden 7.99 12.03 93 46.5% Increase
64 Heidelberg University Hospital at Medical Faculty Heidelberg, Uni Heidelberg, Germany 21.20 11.86 125 -45.6% Decrease
65 Netherlands Cancer Institute (NKI), Netherlands 15.65 11.51 80 -28.4% Decrease
66 West China School/Hospital of Stomatology, SCU, China 6.41 11.50 27 74.6% Increase
67 Sir Run Run Shaw Hospital (SRRSH), ZJU, China 7.11 11.34 55 55.0% Increase
68 Drum Tower Hospital, China 6.40 11.25 40 71.1% Increase
69 Oxford University Hospitals NHS Trust (OUH), United Kingdom (UK) 10.45 10.57 120 -1.6% Decrease
70 University Hospital Bonn (UKB), Uni Bonn, Germany 13.17 10.54 79 -22.1% Decrease
71 University Hospital Tübingen (UKT), Uni Tübingen, Germany 17.21 10.54 87 -40.4% Decrease
72 Catalan Health Institute (ICS), Spain 7.24 10.42 97 40.1% Increase
73 Houston Methodist, United States of America (USA) 11.98 10.42 51 -15.4% Decrease
74 Oslo University Hospital (OUS), Norway 8.79 10.40 73 15.1% Increase
75 Texas Children's Hospital, BCM, United States of America (USA) 9.30 10.30 91 7.7% Increase
76 Tongji Hospital (TJH), HUST, China 7.33 10.25 45 36.1% Increase
77 Shanghai Sixth People's Hospital, SJTU, China 8.57 10.01 33 13.6% Increase
78 University Hospital of Munich (KUM), LMU, Germany 8.18 9.80 116 16.5% Increase
79 UConn Health, United States of America (USA) 13.16 9.78 33 -27.7% Decrease
80 University Hospital of Erlangen, FAU, Germany 14.76 9.74 51 -35.8% Decrease
81 Health Sciences Center (HSC), Utah, United States of America (USA) 38.07 9.63 45 -75.4% Decrease
82 University of Rochester Medical Center (URMC), UR, United States of America (USA) 23.92 9.37 38 -61.9% Decrease
83 University Medical Center Mainz, JGU, Germany 8.85 9.33 62 2.6% Increase
84 Johns Hopkins Health System Corporation (JHHS), United States of America (USA) 9.82 9.32 85 -7.7% Decrease
85 Huashan Hospital, Fudan University, China 5.11 9.09 42 72.9% Increase
86 Ohio State University Wexner Medical Center (OSUWMC), United States of America (USA) 14.10 9.07 42 -37.4% Decrease
87 University of Kansas Medical Center (KUMC), United States of America (USA) 12.21 8.96 41 -28.6% Decrease
88 Jena University Hospital (UKJ), FSU, Germany 4.05 8.81 37 111.8% Increase
89 Roswell Park Cancer Institute (RPCI), United States of America (USA) 7.88 8.74 40 7.8% Increase
90 Shanghai East Hospital, Tongji University, China 3.80 8.72 29 123.5% Increase
91 Sinai Health System, U of T, Canada 9.86 8.70 64 -14.2% Decrease
92 Cancer Institute and Hospital, CAMS & PUMC, China 5.60 8.46 33 47.0% Increase
93 Cambridge University Hospitals NHS Foundation Trust, United Kingdom (UK) 6.07 8.15 115 30.6% Increase
94 Sun Yat-sen Memorial Hospital, SYSU, China 11.55 8.02 31 -32.5% Decrease
95 Melbourne Health, Australia 6.36 7.92 81 21.2% Increase
96 University Hospital Basel (USB), UB, Switzerland 8.73 7.90 58 -12.0% Decrease
97 Spanish National Cancer Research Centre (CNIO), Spain 10.46 7.81 35 -27.4% Decrease
98 University Hospital of Cologne, Germany 7.11 7.78 64 6.5% Increase
99 Medical University of Innsbruck (MUI), Austria 10.31 7.72 41 -27.2% Decrease
100 Nanfang Hospital, China 5.41 7.32 35 31.7% Increase

Footnote

Each year, the Nature Index publishes tables based on counts of high-quality research outputs in the previous calendar year. Users please note:

  1. The data behind the tables are based on a relatively small proportion of total research papers, they cover the natural sciences and health sciences only and outputs are non-normalized (that is, they don’t reflect the size of the country or institution, or its overall research output).
  2. The Nature Index is one indicator of institutional research performance. The metrics of Count and Share used to order Nature Index listings are based on an institution’s or country’s publication output in 145 natural-science and health-science journals. The journals were selected on reputation by an independent panel of leading scientists in their fields. The list is reviewed periodically and journals may be removed or added. Articles from eLife were no longer included in the Nature Index from 2023 after the journal changed its publishing model.
  3. Nature Index recognizes that many other factors must be taken into account when considering research quality and institutional performance; Nature Index metrics alone should not be used to assess institutions or individuals.
  4. Nature Index data and methods are transparent and available under a creative commons licence at nature.com/nature-index/.
  5. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

The Nature Index database undergoes regular updating, corrections, adjustment of institutional hierarchies, and removal of retracted papers and thus the live website can differ from the frozen research leaders.