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Exploiting sweet relief for preeclampsia by targeting autophagy-lysosomal machinery and proteinopathy
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Neutrophils and neutrophil extracellular traps in oral health and disease
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Glutamine-derived aspartate is required for eIF5A hypusination-mediated translation of HIF-1α to induce the polarization of tumor-associated macrophages
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Tetrahydrobiopterin metabolism attenuates ROS generation and radiosensitivity through LDHA S-nitrosylation: novel insight into radiogenic lung injury
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TLR7-dependent eosinophil degranulation links psoriatic skin inflammation to small intestinal inflammatory changes in mice
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Stress-induced epinephrine promotes hepatocellular carcinoma progression via the USP10-PLAGL2 signaling loop
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Glycerol 3-phosphate dehydrogenases (1 and 2) in cancer and other diseases
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Paradigm shift required for translational research on the brain
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Mrgprb2-mediated mast cell activation exacerbates Modic changes by regulating immune niches
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Targeting pyruvate dehydrogenase kinase 1 overcomes EGFR C797S mutation-driven osimertinib resistance in non-small cell lung cancer
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Glutamine-mediated epigenetic regulation of cFLIP underlies resistance to TRAIL in pancreatic cancer
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Editorial
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Enhancer–promoter specificity in gene transcription: molecular mechanisms and disease associations
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3C methods in cancer research: recent advances and future prospects
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Advances in the multimodal analysis of the 3D chromatin structure and gene regulation
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Emerging insights into transcriptional condensates
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Mechanism of phase condensation for chromosome architecture and function
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Overcoming BRAF and CDK4/6 inhibitor resistance by inhibiting MAP3K3-dependent protection against YAP lysosomal degradation
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Loss of SREBP-1c ameliorates iron-induced liver fibrosis by decreasing lipocalin-2
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Central neurocytoma exhibits radial glial cell signatures with FGFR3 hypomethylation and overexpression
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Regulation of cargo selection in exosome biogenesis and its biomedical applications in cancer
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Entosis: the core mechanism and crosstalk with other cell death programs
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Recent advances in CRISPR-based functional genomics for the study of disease-associated genetic variants
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Cargo specificity, regulation, and therapeutic potential of cytoplasmic dynein
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Recent advances in extracellular vesicles for therapeutic cargo delivery
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Transcriptome-based deep learning analysis identifies drug candidates targeting protein synthesis and autophagy for the treatment of muscle wasting disorder
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Ceramide kinase-mediated C1P metabolism attenuates acute liver injury by inhibiting the interaction between KEAP1 and NRF2
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Age-dependent loss of Crls1 causes myopathy and skeletal muscle regeneration failure
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Experimental capture of miRNA targetomes: disease-specific 3′UTR library-based miRNA targetomics for Parkinson’s disease
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Transmembrane proteins with unknown function (TMEMs) as ion channels: electrophysiological properties, structure, and pathophysiological roles
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Methyl-CpG binding domain protein 2 (Mbd2) drives breast cancer progression through the modulation of epithelial-to-mesenchymal transition
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The acute phase reactant orosomucoid-2 directly promotes rheumatoid inflammation
- Ki-Myo Kim
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Extracellular vesicle-mediated transfer of miRNA-1 from primary tumors represses the growth of distant metastases
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Involvement of DJ-1 in the pathogenesis of intervertebral disc degeneration via hexokinase 2-mediated mitophagy
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Acetyl-CoA synthetase 2 contributes to a better prognosis for liver cancer by switching acetate-glucose metabolism
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Cancer-derived exosomal Alu RNA promotes colorectal cancer progression
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Prmt7 regulates the JAK/STAT/Socs3 signaling pathway in postmenopausal cardiomyopathy
- Byeong-Yun Ahn
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Dysregulated CREB3 cleavage at the nuclear membrane induces karyoptosis-mediated cell death
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Immunopathology of and potential therapeutics for secondary hemophagocytic lymphohistiocytosis/macrophage activation syndrome: a translational perspective
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Rebuilding the microenvironment of primary tumors in humans: a focus on stroma
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Advances in single-cell omics and multiomics for high-resolution molecular profiling
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SIRT1 ISGylation accelerates tumor progression by unleashing SIRT1 from the inactive state to promote its deacetylase activity
- Ji An Kang
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The Mst1/2-BNIP3 axis is required for mitophagy induction and neuronal viability under mitochondrial stress
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Advances in cancer DNA methylation analysis with methPLIER: use of non-negative matrix factorization and knowledge-based constraints to enhance biological interpretability
- Ken Takasawa
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Review Article
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Intestinal stem cells: guardians of homeostasis in health and aging amid environmental challenges
- Jiahn Choi
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Tonic excitation by astrocytic GABA causes neuropathic pain by augmenting neuronal activity and glucose metabolismBrowse narrower subjects
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