Biological techniques articles within Experimental & Molecular Medicine

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• Review Article
  01 April 2024 | Open Access

  Recent advances in extracellular vesicles for therapeutic cargo delivery

  • Hyo In Kim
  • , Jinbong Park
  •  & Duo Zhang

• Article
  01 April 2024 | Open Access

  Transcriptome-based deep learning analysis identifies drug candidates targeting protein synthesis and autophagy for the treatment of muscle wasting disorder

  • Min Hak Lee
  • , Bada Lee
  •  & Jin Woo Choi

• Article
  01 April 2024 | Open Access

  Age-dependent loss of Crls1 causes myopathy and skeletal muscle regeneration failure

  • Youngbum Yoo
  • , MyeongHoon Yeon
  •  & Young-Kyo Seo

• Review Article
  05 March 2024 | Open Access

  Advances in single-cell omics and multiomics for high-resolution molecular profiling

  • Jongsu Lim
  • , Chanho Park
  •  & Dong-Sung Lee

• Article
  01 February 2024 | Open Access

  Synaptotagmin-4 induces anhedonic responses to chronic stress via BDNF signaling in the medial prefrontal cortex

  • Jeongseop Kim
  • , Sihwan Seol
  •  & Hyo Jung Kang

• Article
  22 January 2024 | Open Access

  CYB5R3 functions as a tumor suppressor by inducing ER stress-mediated apoptosis in lung cancer cells via the PERK-ATF4 and IRE1α-JNK pathways

  • Joo-Young Im
  • , Soo Jin Kim
  •  & Misun Won

• Review Article
  04 January 2024 | Open Access

  Modification of immune cell-derived exosomes for enhanced cancer immunotherapy: current advances and therapeutic applications

  • Inseong Jung
  • , Sanghee Shin
  •  & Kyungmoo Yea

• Review Article
  02 October 2023 | Open Access

  Spatial transcriptomics in neuroscience

  • Namyoung Jung
  •  & Tae-Kyung Kim

• Article
  02 October 2023 | Open Access

  Optimization of the optical transparency of bones by PACT-based passive tissue clearing

  • Byung-Ho Jin
  • , Jiwon Woo
  •  & Yong Eun Cho

• Review Article
  01 September 2023 | Open Access

  Lipid remodeling of adipose tissue in metabolic health and disease

  • Yoon Keun Cho
  • , Sumin Lee
  •  & Yun-Hee Lee

• Article
  01 September 2023 | Open Access

  Scalable production of tissue-like vascularized liver organoids from human PSCs

  • Sean P. Harrison
  • , Richard Siller
  •  & Gareth J. Sullivan

• Review Article
  23 August 2023 | Open Access

  After cell death: the molecular machinery of efferocytosis

  • Byeongjin Moon
  • , Susumin Yang
  •  & Daeho Park

• Review Article
  01 August 2023 | Open Access

  Genome editing in the treatment of ocular diseases

  • Elliot H. Choi
  • , Susie Suh
  •  & Krzysztof Palczewski

• Review Article
  01 May 2023 | Open Access

  Trends and prospects in mitochondrial genome editing

  • Hong Thi Lam Phan
  • , Hyunji Lee
  •  & Kyoungmi Kim

• Article
  01 February 2023 | Open Access

  Targeted dual base editing with Campylobacter jejuni Cas9 by single AAV-mediated delivery

  • Jiyeon Kweon
  • , An-Hee Jang
  •  & Yongsub Kim

• Article
  04 January 2023 | Open Access

  Stable colonization of Akkermansia muciniphila educates host intestinal microecology and immunity to battle against inflammatory intestinal diseases

  • Bin Wang
  • , Xuheng Chen
  •  & Ming Cui

• Article
  09 December 2022 | Open Access

  SCON—a Short Conditional intrON for conditional knockout with one-step zygote injection

  • Szu-Hsien Sam Wu
  • , Heetak Lee
  •  & Bon-Kyoung Koo

• Article
  08 December 2022 | Open Access

  Loss of KDM5B ameliorates pathological cardiac fibrosis and dysfunction by epigenetically enhancing ATF3 expression

  • Bo Wang
  • , Yong Tan
  •  & Zhenzhen Zhan

• Article
  02 December 2022 | Open Access

  Comparison of cell type distribution between single-cell and single-nucleus RNA sequencing: enrichment of adherent cell types in single-nucleus RNA sequencing

  • Jin-Mi Oh
  • , Minae An
  •  & Woong-Yang Park

• Article
  25 November 2022 | Open Access

  SMP30-mediated synthesis of vitamin C activates the liver PPARα/FGF21 axis to regulate thermogenesis in mice

  • Bonggi Lee
  • , Hye Jin An
  •  & Hae Young Chung

• Review Article
  11 November 2022 | Open Access

  Mouse models of Kras activation in gastric cancer

  • Yoonkyung Won
  •  & Eunyoung Choi

• Editorial
  21 October 2022 | Open Access

  Voyages to map unexplored parts of the epitranscriptomic world

  • Ki-Jun Yoon

• Review Article
  21 October 2022 | Open Access

  Detection technologies for RNA modifications

  • Yan Zhang
  • , Liang Lu
  •  & Xiaoyu Li

• Article
  21 September 2022 | Open Access

  Clusterin negatively modulates mechanical stress-mediated ligamentum flavum hypertrophy through TGF-β1 signaling

  • Chunlei Liu
  • , Peng Li
  •  & Zhongmin Zhang

• Review Article
  08 September 2022 | Open Access

  Metabolic flux between organs measured by arteriovenous metabolite gradients

  • Hosung Bae
  • , Katie Lam
  •  & Cholsoon Jang

• Article
  18 August 2022 | Open Access

  Development of a spontaneous pain indicator based on brain cellular calcium using deep learning

  • Heera Yoon
  • , Myeong Seong Bak
  •  & Sun Kwang Kim

• Article
  09 March 2022 | Open Access

  Multimodal evaluation of an interphotoreceptor retinoid-binding protein-induced mouse model of experimental autoimmune uveitis

  • Jee Myung Yang
  • , KyungA Yun
  •  & Joo Yong Lee

• Article
  15 February 2022 | Open Access

  Hypermethylation of PDX1, EN2, and MSX1 predicts the prognosis of colorectal cancer

  • Yeongun Lee
  • , So Hee Dho
  •  & Lark Kyun Kim

• Article
  20 January 2022 | Open Access

  Application of QPLEX^TM biomarkers in cognitively normal individuals across a broad age range and diverse regions with cerebral amyloid deposition

  • Dongjoon Lee
  • , Jong-Chan Park
  •  & Inhee Mook-Jung

• Review Article
  18 October 2021 | Open Access

  Dissecting single-cell genomes through the clonal organoid technique

  • Jeonghwan Youk
  • , Hyun Woo Kwon
  •  & Young Seok Ju

• Review Article
  18 October 2021 | Open Access

  Strategies for genetic manipulation of adult stem cell-derived organoids

  • Constantin Menche
  •  & Henner F. Farin

• Review Article
  18 October 2021 | Open Access

  Organoids as host models for infection biology – a review of methods

  • Carmen Aguilar
  • , Marta Alves da Silva
  •  & Sina Bartfeld

• Review Article
  18 October 2021 | Open Access

  Organoids in image-based phenotypic chemical screens

  • Ilya Lukonin
  • , Marietta Zinner
  •  & Prisca Liberali

• Article
  29 September 2021 | Open Access

  A human antibody against human endothelin receptor type A that exhibits antitumor potency

  • Man-Seok Ju
  • , Hye-Mi Ahn
  •  & Sang Taek Jung

• Article
  09 July 2021 | Open Access

  Redefining differential roles of MAO-A in dopamine degradation and MAO-B in tonic GABA synthesis

  • Hyun-U Cho
  • , Sunpil Kim
  •  & C. Justin Lee

• Article
  15 April 2021 | Open Access

  DGG-100629 inhibits lung cancer growth by suppressing the NFATc1/DDIAS/STAT3 pathway

  • Joo-Young Im
  • , Bo-Kyung Kim
  •  & Misun Won

• Review Article
  08 April 2021 | Open Access

  Tailoring photosensitive ROS for advanced photodynamic therapy

  • Duc Loc Sai
  • , Jieun Lee
  •  & Young-Pil Kim

• Article
  02 March 2021 | Open Access

  Improved resolution in single-molecule localization microscopy using QD-PAINT

  • Yeonho Chang
  • , Do-Hyeon Kim
  •  & Sung Ho Ryu

• Review Article
  01 March 2021 | Open Access

  Zebrafish as an animal model for biomedical research

  • Tae-Young Choi
  • , Tae-Ik Choi
  •  & Cheol-Hee Kim

• Article
  19 February 2021 | Open Access

  Analysis of transient membrane protein interactions by single-molecule diffusional mobility shift assay

  • Min Gyu Jeong
  • , Kai Zhou
  •  & Sung Ho Ryu

• Article
  01 February 2021 | Open Access

  Modulation of α_Vβ₆ integrin in osteoarthritis-related synovitis and the interaction with VTN_{(381–397 a.a.)} competing for TGF-β1 activation

  • Federica Ciregia
  • , Céline Deroyer
  •  & Dominique de Seny

• Article
  13 January 2021 | Open Access

  Transglutaminase 2 crosslinks the glutathione S-transferase tag, impeding protein–protein interactions of the fused protein

  • Hyo-Jun Kim
  • , Jin-Haeng Lee
  •  & In-Gyu Kim

• Review Article
  26 November 2020 | Open Access

  Single-cell network biology for resolving cellular heterogeneity in human diseases

  • Junha Cha
  •  & Insuk Lee

• Article
  09 November 2020 | Open Access

  Highly efficient and safe genome editing by CRISPR-Cas12a using CRISPR RNA with a ribosyl-2′-O-methylated uridinylate-rich 3′-overhang in mouse zygotes

  • Dae-In Ha
  • , Jeong Mi Lee
  •  & Yong-Sam Kim

• Article
  27 October 2020 | Open Access

  The impact of endotrophin on the progression of chronic liver disease

  • Min Kim
  • , Changhu Lee
  •  & Philipp E. Scherer

• Review Article
  15 July 2020 | Open Access

  Deciphering the star codings: astrocyte manipulation alters mouse behavior

  • Keebum Park
  •  & Sung Joong Lee

• Review Article
  10 July 2020 | Open Access

  Current trends in gene recovery mediated by the CRISPR-Cas system

  • Hyeon-Ki Jang
  • , Beomjong Song
  •  & Sangsu Bae

• Article
  13 May 2020 | Open Access

  MAPS-seq: magnetic bead-assisted parallel single-cell gene expression profiling

  • Munsu Park
  • , Dongin Lee
  •  & Ji Hyun Lee

• Article
  20 January 2020 | Open Access

  Altered platelet proteome in lupus anticoagulant (LA)-positive patients—protein disulfide isomerase and NETosis as new players in LA-related thrombosis

  • Lena Hell
  • , Kristina Lurger
  •  & Maria Zellner

• Article
  15 November 2019 | Open Access

  Deep proteome profiling of the hippocampus in the 5XFAD mouse model reveals biological process alterations and a novel biomarker of Alzheimer’s disease

  • Dong Kyu Kim
  • , Dohyun Han
  •  & Inhee Mook-Jung